Click here to switch to the map view.

The map label for this gene is cbiC

Identifier: 84489971

GI number: 84489971

Start: 1349648

End: 1350271

Strand: Direct

Name: cbiC

Synonym: Msp_1179

Alternate gene names: 84489971

Gene position: 1349648-1350271 (Clockwise)

Preceding gene: 84489969

Following gene: 84489972

Centisome position: 76.36

GC content: 33.01

Gene sequence:

>624_bases
ATGTATAATATGGGAGCATCAACAAAACCAGGATATGATATTGCTAATAAAAGTAGAGAAATTATTAAATCATTAATTGA
TGATGAAACTAAGAATTTAACATATGAGGAACGAGACATAGTTGAACGTGTTGTACATTCTACAGCAGACCCAGAATATG
CCAAACTTGTTAAAATATCACCCACATTTGTAGAAACTGCACTTGATTGTTTTGATAAAAAAGAAGATATTCTTACAGAC
ATAAATATGGTTAAATCAGGAATTACAAGGTATGATGGTAGAGTAATGTGTTATATCCGTGATGAAAGAGCAATTAAATT
GGCTAAAAAAGAAGAAATTACTCGTTCAGCAGCTGCTATGAGAATTGCAGCTGAAGATGGATTTAAAGGAGTAGTTGCAA
TAGGAAACGCTCCAACAGCATTGTTTGAAGTAATGGAATTAGTTGAAGAAGGTCAAATGGATGCACGTGCAGTTGCAGGG
GTACCTGTAGGATTTGTAGGTGCAGCTGATTCTAAAGAAGCATTATCCAAAACAAATATACCTTATGCAATTACAACAGG
ACCTAAAGGTGGAACACCAATTGCAGTTGCAATTATTAATTCATTATTAAATATTAAAAAATAA

Upstream 100 bases:

>100_bases
TAAAATATCATATTTAAATAAATGTTTTAACATAGCCATATATACAAGAAAATAGAGTAAGTTAAAAAACAAAAATTCTA
AAATAAAGGTGTGAAATTAT

Downstream 100 bases:

>100_bases
AAGAGGAGACAATAAATGAAACTTGATAAATCAAAAGAATTATTTGATGAAGCTGTAAATTACCTTCCCGGAGGAGTTAA
TTCACCAGTACGAGCATACA

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MYNMGASTKPGYDIANKSREIIKSLIDDETKNLTYEERDIVERVVHSTADPEYAKLVKISPTFVETALDCFDKKEDILTD
INMVKSGITRYDGRVMCYIRDERAIKLAKKEEITRSAAAMRIAAEDGFKGVVAIGNAPTALFEVMELVEEGQMDARAVAG
VPVGFVGAADSKEALSKTNIPYAITTGPKGGTPIAVAIINSLLNIKK

Sequences:

>Translated_207_residues
MYNMGASTKPGYDIANKSREIIKSLIDDETKNLTYEERDIVERVVHSTADPEYAKLVKISPTFVETALDCFDKKEDILTD
INMVKSGITRYDGRVMCYIRDERAIKLAKKEEITRSAAAMRIAAEDGFKGVVAIGNAPTALFEVMELVEEGQMDARAVAG
VPVGFVGAADSKEALSKTNIPYAITTGPKGGTPIAVAIINSLLNIKK
>Mature_207_residues
MYNMGASTKPGYDIANKSREIIKSLIDDETKNLTYEERDIVERVVHSTADPEYAKLVKISPTFVETALDCFDKKEDILTD
INMVKSGITRYDGRVMCYIRDERAIKLAKKEEITRSAAAMRIAAEDGFKGVVAIGNAPTALFEVMELVEEGQMDARAVAG
VPVGFVGAADSKEALSKTNIPYAITTGPKGGTPIAVAIINSLLNIKK

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22536; Mature: 22536

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNMGASTKPGYDIANKSREIIKSLIDDETKNLTYEERDIVERVVHSTADPEYAKLVKIS
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHCCCCCCHHEEEECC
PTFVETALDCFDKKEDILTDINMVKSGITRYDGRVMCYIRDERAIKLAKKEEITRSAAAM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
RIAAEDGFKGVVAIGNAPTALFEVMELVEEGQMDARAVAGVPVGFVGAADSKEALSKTNI
EEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHCCCCEEEECCCCCHHHHHHCCC
PYAITTGPKGGTPIAVAIINSLLNIKK
CEEEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYNMGASTKPGYDIANKSREIIKSLIDDETKNLTYEERDIVERVVHSTADPEYAKLVKIS
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHCCCCCCHHEEEECC
PTFVETALDCFDKKEDILTDINMVKSGITRYDGRVMCYIRDERAIKLAKKEEITRSAAAM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
RIAAEDGFKGVVAIGNAPTALFEVMELVEEGQMDARAVAGVPVGFVGAADSKEALSKTNI
EEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHCCCCEEEECCCCCHHHHHHCCC
PYAITTGPKGGTPIAVAIINSLLNIKK
CEEEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]