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The map label for this gene is dcd

Identifier: 84489843

GI number: 84489843

Start: 1193863

End: 1194456

Strand: Direct

Name: dcd

Synonym: Msp_1048

Alternate gene names: 84489843

Gene position: 1193863-1194456 (Clockwise)

Preceding gene: 84489842

Following gene: 84489844

Centisome position: 67.55

GC content: 30.81

Gene sequence:

>594_bases
ATGGCAATACTTAGTGATAAGGATATTAAAAAATATTTAGATGAAGGTCGTATTGTAATTGATCCAATTACTAATGAAAA
ACAGATACAACCATCATCTGTAGATTTAAGATTAGGTGACCAATTCAAGGGATTTAAAATAATAACAAAACCATATATAG
ATCCATTTGATAATACAGATCTTGAATCATATATGAGTTCAATTACAGTAGAAGAAGATAAACCATTTATAATACATCCC
GGTGAATTTACATTAGCAACAACATATGAAAATGTGAAATTACCTGATGATATTGTTGCTAGAGTTGAAGGTAGATCTTC
TATGGGTAGACTAGGTATTACCATGCATGTAACGGCAGGTTATATAGATCCAGGATTTGAAGGTAATATTACACTTGAAA
TATCTAATATTGGTAAAATGCCAGTTGCATTATATCCTGGTCAAAGAGTATGTCAAATTGTGTTTGAAACTATGACATCC
CCATCAGAAAAACCATATGGCCATGAAGATAGAGATAGTAAATATATGGGACAAACTGGACCACAAGTAAGTAAAATCAA
GGAAGATTTTGATATAATAAATGGAGGCAAATAA

Upstream 100 bases:

>100_bases
AGGTAGAGCATTTATAGCTGGACGTGAATCACAAACATTACGTGGAACACTAAAACGTATAAATACACGAATCAAAAATA
AAACTCATGAGGAGTAAAAC

Downstream 100 bases:

>100_bases
TGGGAAATGAAGAAGTAATGAGAATATCTAGAAAAAGAGGTTATTTATATCCATCTTTTGAAATATATTCTGGAGTAGCA
GGATTTTATGATTATGGACC

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MAILSDKDIKKYLDEGRIVIDPITNEKQIQPSSVDLRLGDQFKGFKIITKPYIDPFDNTDLESYMSSITVEEDKPFIIHP
GEFTLATTYENVKLPDDIVARVEGRSSMGRLGITMHVTAGYIDPGFEGNITLEISNIGKMPVALYPGQRVCQIVFETMTS
PSEKPYGHEDRDSKYMGQTGPQVSKIKEDFDIINGGK

Sequences:

>Translated_197_residues
MAILSDKDIKKYLDEGRIVIDPITNEKQIQPSSVDLRLGDQFKGFKIITKPYIDPFDNTDLESYMSSITVEEDKPFIIHP
GEFTLATTYENVKLPDDIVARVEGRSSMGRLGITMHVTAGYIDPGFEGNITLEISNIGKMPVALYPGQRVCQIVFETMTS
PSEKPYGHEDRDSKYMGQTGPQVSKIKEDFDIINGGK
>Mature_196_residues
AILSDKDIKKYLDEGRIVIDPITNEKQIQPSSVDLRLGDQFKGFKIITKPYIDPFDNTDLESYMSSITVEEDKPFIIHPG
EFTLATTYENVKLPDDIVARVEGRSSMGRLGITMHVTAGYIDPGFEGNITLEISNIGKMPVALYPGQRVCQIVFETMTSP
SEKPYGHEDRDSKYMGQTGPQVSKIKEDFDIINGGK

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=192, Percent_Identity=43.2291666666667, Blast_Score=160, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_METST (Q2NFH1)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448075.1
- ProteinModelPortal:   Q2NFH1
- SMR:   Q2NFH1
- STRING:   Q2NFH1
- GeneID:   3855168
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1048
- NMPDR:   fig|339860.6.peg.1003
- eggNOG:   arNOG05800
- HOGENOM:   HBG553199
- OMA:   FSGHVTL
- PhylomeDB:   Q2NFH1
- ProtClustDB:   PRK00416
- BioCyc:   MSTA339860:MSP_1048-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR010550
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF06559 DCD; PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 22041; Mature: 21910

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILSDKDIKKYLDEGRIVIDPITNEKQIQPSSVDLRLGDQFKGFKIITKPYIDPFDNTD
CCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCC
LESYMSSITVEEDKPFIIHPGEFTLATTYENVKLPDDIVARVEGRSSMGRLGITMHVTAG
HHHHHHHEEEECCCCEEEECCCEEEEEECCCCCCCHHHHHEECCCCCCCCEEEEEEEEEC
YIDPGFEGNITLEISNIGKMPVALYPGQRVCQIVFETMTSPSEKPYGHEDRDSKYMGQTG
CCCCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PQVSKIKEDFDIINGGK
CHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AILSDKDIKKYLDEGRIVIDPITNEKQIQPSSVDLRLGDQFKGFKIITKPYIDPFDNTD
CCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCC
LESYMSSITVEEDKPFIIHPGEFTLATTYENVKLPDDIVARVEGRSSMGRLGITMHVTAG
HHHHHHHEEEECCCCEEEECCCEEEEEECCCCCCCHHHHHEECCCCCCCCEEEEEEEEEC
YIDPGFEGNITLEISNIGKMPVALYPGQRVCQIVFETMTSPSEKPYGHEDRDSKYMGQTG
CCCCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PQVSKIKEDFDIINGGK
CHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA