Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 83721661

GI number: 83721661

Start: 884841

End: 885341

Strand: Reverse

Name: lspA [H]

Synonym: BTH_I0769

Alternate gene names: 83721661

Gene position: 885341-884841 (Counterclockwise)

Preceding gene: 83720304

Following gene: 83718888

Centisome position: 23.24

GC content: 65.87

Gene sequence:

>501_bases
ATGGCGAAGACCCTGTCGAAATCCTCGGGCGGCGCGCTTGCGCCGTGGCTCGGCATCTCGCTGATCGTGATCCTGTTCGA
TCAGTTGACGAAGATCGCCGTGCTGAAGACCTTCGCGTACGGCGCGATGCATCAACTCACGCCGTTCTTCAACCTGACGC
TGATCTACAACCGCGGGGCCGCGTTCGGCTTTCTCGCGACCGCGGGCGGCTGGCAGCGCTGGGCGTTCACCGCGCTCGGC
ATCGGCGCGACGCTCGTGATCTGCTATCTGCTCAAGCGCCACGGGCACCAGCGCCTCTTCAGCCTGTCGCTCGCGCTGAT
TCTCGGCGGCGCGCTCGGCAACGTGATCGATCGCCTGATCTACGGTCACGTGATCGACTTCCTCGATTTCCACGTCGGCG
CGTGGCACTGGCCCGCGTTCAACCTCGCCGACTCCGCGATCACGGTGGGCGCGGTGCTCCTCATCTACGACGAGTTGCGT
CGCGTGCGCGGCGCGCGCTAG

Upstream 100 bases:

>100_bases
CTACCGCGAGGACGTCGGCGCGCATGCCGATCATCCGACGCTCTGCGGCCGCTGCTTCTCCAACCTGTTCGAAAACGGCG
AAACCCGGAGCGCTGCGTAA

Downstream 100 bases:

>100_bases
GCGCATACACTTCGCGCAGGGGCCGGCGCGCGCCGGCCCCACGTGCTTTCGGAGGCCTCAGTTGGCACACGCAGAACTCG
CAGGAAAACACCTCGTCCTC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MAKTLSKSSGGALAPWLGISLIVILFDQLTKIAVLKTFAYGAMHQLTPFFNLTLIYNRGAAFGFLATAGGWQRWAFTALG
IGATLVICYLLKRHGHQRLFSLSLALILGGALGNVIDRLIYGHVIDFLDFHVGAWHWPAFNLADSAITVGAVLLIYDELR
RVRGAR

Sequences:

>Translated_166_residues
MAKTLSKSSGGALAPWLGISLIVILFDQLTKIAVLKTFAYGAMHQLTPFFNLTLIYNRGAAFGFLATAGGWQRWAFTALG
IGATLVICYLLKRHGHQRLFSLSLALILGGALGNVIDRLIYGHVIDFLDFHVGAWHWPAFNLADSAITVGAVLLIYDELR
RVRGAR
>Mature_165_residues
AKTLSKSSGGALAPWLGISLIVILFDQLTKIAVLKTFAYGAMHQLTPFFNLTLIYNRGAAFGFLATAGGWQRWAFTALGI
GATLVICYLLKRHGHQRLFSLSLALILGGALGNVIDRLIYGHVIDFLDFHVGAWHWPAFNLADSAITVGAVLLIYDELRR
VRGAR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=163, Percent_Identity=41.7177914110429, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18157; Mature: 18025

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTLSKSSGGALAPWLGISLIVILFDQLTKIAVLKTFAYGAMHQLTPFFNLTLIYNRGA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEEECCC
AFGFLATAGGWQRWAFTALGIGATLVICYLLKRHGHQRLFSLSLALILGGALGNVIDRLI
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGHVIDFLDFHVGAWHWPAFNLADSAITVGAVLLIYDELRRVRGAR
HHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKTLSKSSGGALAPWLGISLIVILFDQLTKIAVLKTFAYGAMHQLTPFFNLTLIYNRGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEEECCC
AFGFLATAGGWQRWAFTALGIGATLVICYLLKRHGHQRLFSLSLALILGGALGNVIDRLI
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGHVIDFLDFHVGAWHWPAFNLADSAITVGAVLLIYDELRRVRGAR
HHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA