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The map label for this gene is napA [H]

Identifier: 83721628

GI number: 83721628

Start: 2624359

End: 2625693

Strand: Reverse

Name: napA [H]

Synonym: BTH_I2332

Alternate gene names: 83721628

Gene position: 2625693-2624359 (Counterclockwise)

Preceding gene: 83720094

Following gene: 83719903

Centisome position: 68.93

GC content: 70.04

Gene sequence:

>1335_bases
ATGACTGACTGGATACTGCAGCTGTGCGTCGTGGTCATCGTCGCATTCGCGCTCGGCGCGCTCGCGCAACGGTTCGGGCC
GGGCCGGGTCGTCGGCGAACTGCTCGCCGGGCTGCTGCTTGGCCCGTCGGCGTTCGGCACGCTCACCGTGGCCGGGCACG
GCGCGCTGATCGGCGAGGACACGGCCGCGCTCCTGTCGAGGCTCGGCGAGCTCGGGCTCGTGTTCCTGATGTTTCAGACG
GGCATGCACATTACCTGGCGGATTCCGCAAAAGCGCTCGGCCGGGTTCGTCGCGACCGTCATCGCGGGATTCGGCATGGC
GCTGCCGTTCGCGGCGGGCTGCGCGATCGCCGTCGCGTCATCCGGATCGTTCCGGCCGCAGGCGTCGCATCTCGCCTATG
TGCTGTTCTGCGGCATCGCGCTGTCCGTGTCGGCGTTGCCCGTCATGATGCGCATCGTCGCGGATGCGCGCATCGCCGAG
CGCCCGTCGGCGACGCTGTCGATTCTCTCGGCGACGTTGACCGACTCGCTCGGCTGGCTGATGCTCGCGGCCGTCGGCGC
GATCGCGACCTCGGGTCTGTCGCCCGCATCGACGGTGCGCGCGATGTGCGCGCTCGCCGCGTTCGTCGTCGTGTCGATCA
CGCTCGTGCGCAAGATCGTCCTCGGGCTGCTCGATCGGACCCGCCGGGCCGGCAGCGGCTCCGCCACGTTGATCTGCGCG
CTCTGCTACGTGCTGCTGTCGTCGTGGGCCGCGTCGCGGCTCGGTTTTCACGGCGCGTTCGGCGCGCTCGTCGCGGCCGC
CAACCTGGCGGGCCGAGACGATCTGCGGCGGTTGTGGGACGCGCGCTTCGCGGGACTGGCCGACCTCGTCCTGATTCCGC
TCTTTTTCGTGAGCATGGGCTTTCAGGCGTCGTTTTCGGCGCTCGACACGGGCGCGGCCTGGGGATGGCTCGCCGCCTTC
CTGATCGGCGGCGTGGCGGCGAAATTCGCCGGCTGCTACGCGGGCGCGCGACTGTGCGGCATCGACCGCGCGGAAGCGAC
GCTCATCGGCGTGCTGATGAACTGCCGCGGCACGGTCGAGCTGATGGTGCTCGCGATCGGCCTCCAGTTGCGGATCATCC
CCGCTTCGCTGTACACGGTTCTGCTGATCGCGACGCTTGCGATGACATGGTTGAGCGCGATGTCGACCCACCGGCTCGCG
AAGCAGAGCCCGCTACGCTCGCCGCAGGCGGGTGCGTGCGATTCGCCGGCGGAATTTCGCGCGCCGCAGGCGCATGCGGC
CGGCGGCGACGCCCGTCTGCCGGGATTGCCGGAGGTATCGCGCCCGTCGCGATAA

Upstream 100 bases:

>100_bases
GTCGCCGCGATGTAGCCGCCGCGCGCAGGCCGGTCGCCGCGGCCGAGCCGCCGGCATCGCCGGCGGGCACGCGCGCATCG
AACGCGAGGAGCGAACGAAG

Downstream 100 bases:

>100_bases
ATGCCCATGGATACCGTCGTTCCGCTTCTTTCCGACTCCGCCGCGCGCTGGCTGCCGCTCGCGCTGTCCGAGCAGGTGAG
CGGCAAGGCCCCGCTCGCCG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTDWILQLCVVVIVAFALGALAQRFGPGRVVGELLAGLLLGPSAFGTLTVAGHGALIGEDTAALLSRLGELGLVFLMFQT
GMHITWRIPQKRSAGFVATVIAGFGMALPFAAGCAIAVASSGSFRPQASHLAYVLFCGIALSVSALPVMMRIVADARIAE
RPSATLSILSATLTDSLGWLMLAAVGAIATSGLSPASTVRAMCALAAFVVVSITLVRKIVLGLLDRTRRAGSGSATLICA
LCYVLLSSWAASRLGFHGAFGALVAAANLAGRDDLRRLWDARFAGLADLVLIPLFFVSMGFQASFSALDTGAAWGWLAAF
LIGGVAAKFAGCYAGARLCGIDRAEATLIGVLMNCRGTVELMVLAIGLQLRIIPASLYTVLLIATLAMTWLSAMSTHRLA
KQSPLRSPQAGACDSPAEFRAPQAHAAGGDARLPGLPEVSRPSR

Sequences:

>Translated_444_residues
MTDWILQLCVVVIVAFALGALAQRFGPGRVVGELLAGLLLGPSAFGTLTVAGHGALIGEDTAALLSRLGELGLVFLMFQT
GMHITWRIPQKRSAGFVATVIAGFGMALPFAAGCAIAVASSGSFRPQASHLAYVLFCGIALSVSALPVMMRIVADARIAE
RPSATLSILSATLTDSLGWLMLAAVGAIATSGLSPASTVRAMCALAAFVVVSITLVRKIVLGLLDRTRRAGSGSATLICA
LCYVLLSSWAASRLGFHGAFGALVAAANLAGRDDLRRLWDARFAGLADLVLIPLFFVSMGFQASFSALDTGAAWGWLAAF
LIGGVAAKFAGCYAGARLCGIDRAEATLIGVLMNCRGTVELMVLAIGLQLRIIPASLYTVLLIATLAMTWLSAMSTHRLA
KQSPLRSPQAGACDSPAEFRAPQAHAAGGDARLPGLPEVSRPSR
>Mature_443_residues
TDWILQLCVVVIVAFALGALAQRFGPGRVVGELLAGLLLGPSAFGTLTVAGHGALIGEDTAALLSRLGELGLVFLMFQTG
MHITWRIPQKRSAGFVATVIAGFGMALPFAAGCAIAVASSGSFRPQASHLAYVLFCGIALSVSALPVMMRIVADARIAER
PSATLSILSATLTDSLGWLMLAAVGAIATSGLSPASTVRAMCALAAFVVVSITLVRKIVLGLLDRTRRAGSGSATLICAL
CYVLLSSWAASRLGFHGAFGALVAAANLAGRDDLRRLWDARFAGLADLVLIPLFFVSMGFQASFSALDTGAAWGWLAAFL
IGGVAAKFAGCYAGARLCGIDRAEATLIGVLMNCRGTVELMVLAIGLQLRIIPASLYTVLLIATLAMTWLSAMSTHRLAK
QSPLRSPQAGACDSPAEFRAPQAHAAGGDARLPGLPEVSRPSR

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=432, Percent_Identity=24.3055555555556, Blast_Score=141, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 45996; Mature: 45865

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDWILQLCVVVIVAFALGALAQRFGPGRVVGELLAGLLLGPSAFGTLTVAGHGALIGED
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCC
TAALLSRLGELGLVFLMFQTGMHITWRIPQKRSAGFVATVIAGFGMALPFAAGCAIAVAS
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEC
SGSFRPQASHLAYVLFCGIALSVSALPVMMRIVADARIAERPSATLSILSATLTDSLGWL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MLAAVGAIATSGLSPASTVRAMCALAAFVVVSITLVRKIVLGLLDRTRRAGSGSATLICA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LCYVLLSSWAASRLGFHGAFGALVAAANLAGRDDLRRLWDARFAGLADLVLIPLFFVSMG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FQASFSALDTGAAWGWLAAFLIGGVAAKFAGCYAGARLCGIDRAEATLIGVLMNCRGTVE
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHH
LMVLAIGLQLRIIPASLYTVLLIATLAMTWLSAMSTHRLAKQSPLRSPQAGACDSPAEFR
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHC
APQAHAAGGDARLPGLPEVSRPSR
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDWILQLCVVVIVAFALGALAQRFGPGRVVGELLAGLLLGPSAFGTLTVAGHGALIGED
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCC
TAALLSRLGELGLVFLMFQTGMHITWRIPQKRSAGFVATVIAGFGMALPFAAGCAIAVAS
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEC
SGSFRPQASHLAYVLFCGIALSVSALPVMMRIVADARIAERPSATLSILSATLTDSLGWL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MLAAVGAIATSGLSPASTVRAMCALAAFVVVSITLVRKIVLGLLDRTRRAGSGSATLICA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LCYVLLSSWAASRLGFHGAFGALVAAANLAGRDDLRRLWDARFAGLADLVLIPLFFVSMG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FQASFSALDTGAAWGWLAAFLIGGVAAKFAGCYAGARLCGIDRAEATLIGVLMNCRGTVE
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHH
LMVLAIGLQLRIIPASLYTVLLIATLAMTWLSAMSTHRLAKQSPLRSPQAGACDSPAEFR
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHC
APQAHAAGGDARLPGLPEVSRPSR
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]