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The map label for this gene is degS [H]

Identifier: 83721543

GI number: 83721543

Start: 3314755

End: 3316977

Strand: Reverse

Name: degS [H]

Synonym: BTH_I2882

Alternate gene names: 83721543

Gene position: 3316977-3314755 (Counterclockwise)

Preceding gene: 83721613

Following gene: 83720079

Centisome position: 87.08

GC content: 67.39

Gene sequence:

>2223_bases
GTGCGCGCGATTGCGCCTCGCTTTCCCGCATTCTCTCCCTGGGCGGTACTCGAAGCGCGCCGAGGCCGTCATGTCGGGAT
CGGGGCTTCGACGCGAGCGTTTCTACGTCGACGTCGGCGTCGGCGTCGGCGTCGGCGTCCGAGGCGGGCGAGCCGAAACC
GATGCGTCGACACGTGTGACGCGAGCGCCGCCGCTCGCTCCAACGTACGTCGCCCGAAACATTCCCGGCAACCGACCGCC
GGCGGCGCACGGCCGGCTTCGTCAAAAGCTCGCGCCCATCTGCCGAATACCGCTGGCCGTCAGCCTGCAACCGGTTCTGC
GCCGAGGTTTCGTTGTTGCGCCGCAACGGCACGCCCGTCGCTTCGCGCGGCCTGTGCGCGTGACCCCGATACACCGCCGC
TTTTCACGAAGCAAGATCGATTTCATAATAGATGCGCTGTCCGGGAGCGCGCGGCATGTCCGAGCGTGCAAGCTTGCCGA
ATGAGGAGAACCGGAATGGGCGAGTTGGCGGACGAATCGAGAATCTTCCTGTCGACGCTGCAGCCTGAGCGCCGCGAGCG
CCGGCTCGCGATGACGGCCGTGGCGCTCTCCGTGGTCCTGTTCGCGACGCTCGCACCATTCGTGCGCATCCAGATGCCGC
AGGTGTGGGCGTTCATCCCGATCTACCAGTCGGCGATCGTGATCTGTGATCTCATCACGGCGGGCCTGCTGCTCGGTCAA
TTCGGCATTTTGCGCACCACGTCGCTCGTCGTGCTCGCCGGCGGCTATCTGTTCACGGCGTTCATGGCGAGCGTGCACAT
GCTCACGTTTCCCGGCCTGTTCCTGCCGAGCGGGTTGCTCGACGCGGGCCCGCAGACGACTGCGTGGCTCTACATGTTCT
GGCACAGCGGCTTTCCGCTTTGCGTCGCCCTCTACACGCTCGTCAGTCGCCGCGAGCGAGGGGCGCCGCTCTATACGGGG
CGGCTCGCGTTTCCCGTGGGCGTTTGCATCGGCACGGCGCTCGTCGCGACGGGCGTTTTCGCCGCGCTCGCGACGAGCGG
CCGTGAGCTGTTGCCGGCGATCATGGACAATCATCACTACACGCCGCTCATGCGCGGCGTCGTGACGACCGTCTGGCTGA
TGACGCTCGGCGCGCTGATCCTGCTCGCATCGCGCCGGCCGCATTCGGTGCTCGATCTGTGGCTCATCGTCGTGCTGTGC
GCGTGGCTGCTCGATATCGCGCTGTCGGCCGTTCTCAATCACGGGCGTTTCGATCTCGGCTTCTACGCGGGGCGCATCTA
CGGCCTCGTCGCGTCGAGCTTCGTGCTGCTCGCGCTGTTGCTCGAAAACGGCAAGCTGTACGCGCGCACGGTCCACGCGT
TGCAGGGCGAGCGGATCGAGCGCCGGCGCGTGCAAGAGAAAACCGTCCGGTTGAACGAGGCGAACGAGCTGCTCGAGCAG
CGCGTTGCCGAACGCACGAGCGAGTTGCAGACCGCGAACGACGAGCTGCGGCGGGAGATCGTTGAGCGCGAGCGCGCGGA
GGAAGCGCTCGCCCGTTCGCGCGAAGAGTTGCGCGAGATCGCCGCGATCAGTTCGACCGCGCGCGAGCAGGAGCGCGGCC
GGATCGCACGCGAGCTGCACGACGAGCTTGCGCAGACGCTCGCGATGCTGCGGCTCGATCTCGAACGCGTGTCGACGACG
GGCAACGAGCTCGCCGGGCGCTTCACGGAGATGCGCGGGCTGCTTGACGGCGCGGTTGCGGCGACGCGCCGGATCGCGTC
GGATCTGCGCCCGCTGATGCTCGACGATCTCGGGCTCGTGCCGGCCATCCAGTGGCTCGTGCAGGCGTTCCAGCAGCGGC
ACGGGATCGGCTGCACGCTGATCGTCGATCCGCCCGAGCTCGATCTCGTCGAGCCGCAGGCGAGCACGACGTTTCGCATC
CTGCAGGAATCGCTGACGAATGTCGGGCGCCATGCTCGCGCATCGCATGTCGACATCCGGCTCATCGCCGACGATCGCGA
GGTGATGCTGAGCGTGCGCGACAACGGCGTCGGCTTCGATACGGAGAACCCGCGCAAGCCGAATTCGTTCGGACTCGTCG
GCCTGCGCGAGCGCGCGTACCTGGTGCAGGGCACGCTGTCGGTGCAGACGGCGCCGGGGCGGGGGACTGCGATCGAGGTC
CACATCCCGCTCGTTCGGCCGCACGAATTGACCGTCCTGCAAAGCGGCGAGCTGCGCGAATGA

Upstream 100 bases:

>100_bases
CGCGAATGCCGCGCGCGCATCGGCGGGGGCGAGACAGACGGGCGCGATGTCGCGGTAATCGATCTTCTCGCGCCGCAGCG
CATTGACGAGCCGATATTCG

Downstream 100 bases:

>100_bases
CGTGACGGCTTTGCGCATCGCGGCCGCCGCGCGCATCGGCGGCACGCGCCCGGGCCGGGCGGAGCGATCTTGCCGCCTCG
CCTCGTCACCGGGCCGCGCG

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 740; Mature: 740

Protein sequence:

>740_residues
MRAIAPRFPAFSPWAVLEARRGRHVGIGASTRAFLRRRRRRRRRRRPRRASRNRCVDTCDASAAARSNVRRPKHSRQPTA
GGARPASSKARAHLPNTAGRQPATGSAPRFRCCAATARPSLRAACARDPDTPPLFTKQDRFHNRCAVRERAACPSVQACR
MRRTGMGELADESRIFLSTLQPERRERRLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSAIVICDLITAGLLLGQ
FGILRTTSLVVLAGGYLFTAFMASVHMLTFPGLFLPSGLLDAGPQTTAWLYMFWHSGFPLCVALYTLVSRRERGAPLYTG
RLAFPVGVCIGTALVATGVFAALATSGRELLPAIMDNHHYTPLMRGVVTTVWLMTLGALILLASRRPHSVLDLWLIVVLC
AWLLDIALSAVLNHGRFDLGFYAGRIYGLVASSFVLLALLLENGKLYARTVHALQGERIERRRVQEKTVRLNEANELLEQ
RVAERTSELQTANDELRREIVERERAEEALARSREELREIAAISSTAREQERGRIARELHDELAQTLAMLRLDLERVSTT
GNELAGRFTEMRGLLDGAVAATRRIASDLRPLMLDDLGLVPAIQWLVQAFQQRHGIGCTLIVDPPELDLVEPQASTTFRI
LQESLTNVGRHARASHVDIRLIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGTLSVQTAPGRGTAIEV
HIPLVRPHELTVLQSGELRE

Sequences:

>Translated_740_residues
MRAIAPRFPAFSPWAVLEARRGRHVGIGASTRAFLRRRRRRRRRRRPRRASRNRCVDTCDASAAARSNVRRPKHSRQPTA
GGARPASSKARAHLPNTAGRQPATGSAPRFRCCAATARPSLRAACARDPDTPPLFTKQDRFHNRCAVRERAACPSVQACR
MRRTGMGELADESRIFLSTLQPERRERRLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSAIVICDLITAGLLLGQ
FGILRTTSLVVLAGGYLFTAFMASVHMLTFPGLFLPSGLLDAGPQTTAWLYMFWHSGFPLCVALYTLVSRRERGAPLYTG
RLAFPVGVCIGTALVATGVFAALATSGRELLPAIMDNHHYTPLMRGVVTTVWLMTLGALILLASRRPHSVLDLWLIVVLC
AWLLDIALSAVLNHGRFDLGFYAGRIYGLVASSFVLLALLLENGKLYARTVHALQGERIERRRVQEKTVRLNEANELLEQ
RVAERTSELQTANDELRREIVERERAEEALARSREELREIAAISSTAREQERGRIARELHDELAQTLAMLRLDLERVSTT
GNELAGRFTEMRGLLDGAVAATRRIASDLRPLMLDDLGLVPAIQWLVQAFQQRHGIGCTLIVDPPELDLVEPQASTTFRI
LQESLTNVGRHARASHVDIRLIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGTLSVQTAPGRGTAIEV
HIPLVRPHELTVLQSGELRE
>Mature_740_residues
MRAIAPRFPAFSPWAVLEARRGRHVGIGASTRAFLRRRRRRRRRRRPRRASRNRCVDTCDASAAARSNVRRPKHSRQPTA
GGARPASSKARAHLPNTAGRQPATGSAPRFRCCAATARPSLRAACARDPDTPPLFTKQDRFHNRCAVRERAACPSVQACR
MRRTGMGELADESRIFLSTLQPERRERRLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSAIVICDLITAGLLLGQ
FGILRTTSLVVLAGGYLFTAFMASVHMLTFPGLFLPSGLLDAGPQTTAWLYMFWHSGFPLCVALYTLVSRRERGAPLYTG
RLAFPVGVCIGTALVATGVFAALATSGRELLPAIMDNHHYTPLMRGVVTTVWLMTLGALILLASRRPHSVLDLWLIVVLC
AWLLDIALSAVLNHGRFDLGFYAGRIYGLVASSFVLLALLLENGKLYARTVHALQGERIERRRVQEKTVRLNEANELLEQ
RVAERTSELQTANDELRREIVERERAEEALARSREELREIAAISSTAREQERGRIARELHDELAQTLAMLRLDLERVSTT
GNELAGRFTEMRGLLDGAVAATRRIASDLRPLMLDDLGLVPAIQWLVQAFQQRHGIGCTLIVDPPELDLVEPQASTTFRI
LQESLTNVGRHARASHVDIRLIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGTLSVQTAPGRGTAIEV
HIPLVRPHELTVLQSGELRE

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=225, Percent_Identity=28.8888888888889, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87082311, Length=241, Percent_Identity=31.1203319502075, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788812, Length=200, Percent_Identity=30, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82237; Mature: 82237

Theoretical pI: Translated: 11.26; Mature: 11.26

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIAPRFPAFSPWAVLEARRGRHVGIGASTRAFLRRRRRRRRRRRPRRASRNRCVDTCD
CCCCCCCCCCCCCHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHCC
ASAAARSNVRRPKHSRQPTAGGARPASSKARAHLPNTAGRQPATGSAPRFRCCAATARPS
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHCCCH
LRAACARDPDTPPLFTKQDRFHNRCAVRERAACPSVQACRMRRTGMGELADESRIFLSTL
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHC
QPERRERRLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSAIVICDLITAGLLLGQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGILRTTSLVVLAGGYLFTAFMASVHMLTFPGLFLPSGLLDAGPQTTAWLYMFWHSGFPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHCCCCCCHHEEEHHHHCCCHH
CVALYTLVSRRERGAPLYTGRLAFPVGVCIGTALVATGVFAALATSGRELLPAIMDNHHY
HHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
TPLMRGVVTTVWLMTLGALILLASRRPHSVLDLWLIVVLCAWLLDIALSAVLNHGRFDLG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FYAGRIYGLVASSFVLLALLLENGKLYARTVHALQGERIERRRVQEKTVRLNEANELLEQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
RVAERTSELQTANDELRREIVERERAEEALARSREELREIAAISSTAREQERGRIARELH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELAQTLAMLRLDLERVSTTGNELAGRFTEMRGLLDGAVAATRRIASDLRPLMLDDLGLV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
PAIQWLVQAFQQRHGIGCTLIVDPPELDLVEPQASTTFRILQESLTNVGRHARASHVDIR
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
LIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGTLSVQTAPGRGTAIEV
EEECCCEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEEEEECCCCCCEEEE
HIPLVRPHELTVLQSGELRE
EEECCCCCEEEEECCCCCCC
>Mature Secondary Structure
MRAIAPRFPAFSPWAVLEARRGRHVGIGASTRAFLRRRRRRRRRRRPRRASRNRCVDTCD
CCCCCCCCCCCCCHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHCC
ASAAARSNVRRPKHSRQPTAGGARPASSKARAHLPNTAGRQPATGSAPRFRCCAATARPS
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHCCCH
LRAACARDPDTPPLFTKQDRFHNRCAVRERAACPSVQACRMRRTGMGELADESRIFLSTL
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHC
QPERRERRLAMTAVALSVVLFATLAPFVRIQMPQVWAFIPIYQSAIVICDLITAGLLLGQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGILRTTSLVVLAGGYLFTAFMASVHMLTFPGLFLPSGLLDAGPQTTAWLYMFWHSGFPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHCCCCCCHHEEEHHHHCCCHH
CVALYTLVSRRERGAPLYTGRLAFPVGVCIGTALVATGVFAALATSGRELLPAIMDNHHY
HHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
TPLMRGVVTTVWLMTLGALILLASRRPHSVLDLWLIVVLCAWLLDIALSAVLNHGRFDLG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FYAGRIYGLVASSFVLLALLLENGKLYARTVHALQGERIERRRVQEKTVRLNEANELLEQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
RVAERTSELQTANDELRREIVERERAEEALARSREELREIAAISSTAREQERGRIARELH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELAQTLAMLRLDLERVSTTGNELAGRFTEMRGLLDGAVAATRRIASDLRPLMLDDLGLV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
PAIQWLVQAFQQRHGIGCTLIVDPPELDLVEPQASTTFRILQESLTNVGRHARASHVDIR
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
LIADDREVMLSVRDNGVGFDTENPRKPNSFGLVGLRERAYLVQGTLSVQTAPGRGTAIEV
EEECCCEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEEEEECCCCCCEEEE
HIPLVRPHELTVLQSGELRE
EEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]