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The map label for this gene is queD [H]

Identifier: 83721427

GI number: 83721427

Start: 168678

End: 169130

Strand: Direct

Name: queD [H]

Synonym: BTH_I0139

Alternate gene names: 83721427

Gene position: 168678-169130 (Clockwise)

Preceding gene: 83720295

Following gene: 83719058

Centisome position: 4.43

GC content: 63.13

Gene sequence:

>453_bases
GTGCTGATTACCCGAAAACTCGAATTCGACGCGGGGCACCGCATCCCCGATCACCGCAGCCAGTGCCGGAATCTGCACGG
GCATCGCTACGTGCTCGAAATCACGCTGCGCGGCGATCTCGTCGAGACCGAGGGCGCGCCCGACCGCGGGATGGTGATGG
ATTTCGCGGACGTGAAGGGGCTCGCGATGGAGCATCTCGTCAGCAAGTGGGATCACGCGTTTCTCGTCTATGCGCGCGAC
GAAATCGTGCGCTCGTTCCTCGAAAAGATGGCCGATCACAAGACGGTCGTCCTCGACCGGATTCCGACCGTCGAGAATCT
CGCGGCGATCGCGTTCGACATCCTCGCGAACGTGTACGACGCGCACTATGGCGTCAATCTGCGCCTCGAGCGCGTGCGTC
TGTACGAAACGCCGAACTGCTGGGCCGACGTCGAGCGCGATCCGCGCGTCTGA

Upstream 100 bases:

>100_bases
AAGCTCGCGATCGACTGGTGCAAGCGCCATCCGCAGTGGCGGCTGTCGATGCAGACGCACAAGTACCTGAACATTCCTTG
AGCCTTACGCTTCATTCATC

Downstream 100 bases:

>100_bases
TTTCGCGCATCTGGCGCGGCCGCCGCGCGGTCGGCCGCCGCGCGTTTCCGCGTGCGCGAGGCGCTCGCGTGACGCCCTTC
GCGTCTTCCACCTGATCCGC

Product: 6-pyruvoyl tetrahydrobiopterin synthase

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVETEGAPDRGMVMDFADVKGLAMEHLVSKWDHAFLVYARD
EIVRSFLEKMADHKTVVLDRIPTVENLAAIAFDILANVYDAHYGVNLRLERVRLYETPNCWADVERDPRV

Sequences:

>Translated_150_residues
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVETEGAPDRGMVMDFADVKGLAMEHLVSKWDHAFLVYARD
EIVRSFLEKMADHKTVVLDRIPTVENLAAIAFDILANVYDAHYGVNLRLERVRLYETPNCWADVERDPRV
>Mature_150_residues
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVETEGAPDRGMVMDFADVKGLAMEHLVSKWDHAFLVYARD
EIVRSFLEKMADHKTVVLDRIPTVENLAAIAFDILANVYDAHYGVNLRLERVRLYETPNCWADVERDPRV

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 17382; Mature: 17382

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVETEGAPDRGMVMDFADVKG
CEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCEEEEHHHHHH
LAMEHLVSKWDHAFLVYARDEIVRSFLEKMADHKTVVLDRIPTVENLAAIAFDILANVYD
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
AHYGVNLRLERVRLYETPNCWADVERDPRV
HCCCCCEEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVETEGAPDRGMVMDFADVKG
CEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCEEEEHHHHHH
LAMEHLVSKWDHAFLVYARDEIVRSFLEKMADHKTVVLDRIPTVENLAAIAFDILANVYD
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
AHYGVNLRLERVRLYETPNCWADVERDPRV
HCCCCCEEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA