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The map label for this gene is dppA [H]

Identifier: 83721240

GI number: 83721240

Start: 252601

End: 254229

Strand: Direct

Name: dppA [H]

Synonym: BTH_I0220

Alternate gene names: 83721240

Gene position: 252601-254229 (Clockwise)

Preceding gene: 83719245

Following gene: 83720330

Centisome position: 6.63

GC content: 62.74

Gene sequence:

>1629_bases
ATGGAACATAACCGTCTGTTGCGCGCACTGCGTGTTACCGCCATCGCGGGCGTTGCAGCGGCATCGTTTGGCGTCGCGGG
TTCTGCATTCGCACAGATCCCGAACAAAACGCTCGTCTACTGCTCAGAAGGCAGCCCGGCGGGCTTCGATTCCGCGCAGT
TCACGACGGGCGTCGATTTCACCGCGTCAACGTTCCCGATCTACAACCGCCTCGTCGAGTTCGAGCGCGGCGGCACGAAG
GTCGAGCCCGGCCTCGCCGAGAAGTGGGACATCTCGCCCGACGGCAAGGTCTACACGTTCCATCTGCGCCACGGCGTCAA
GTTCCATACGACCGATTTCTTCAAGCCGACGCGCGAATTCAACGCGGACGACGTCGCGTTCACGTTCGAGCGGATGATCG
ATCCGAACCAGCCGTTTCGCAAGGCGTATCCGGTGTCGTTCCCGTACTTCACCGACATGGGCCTGGACAAGCTGATCGTG
AAGATCGAGAAGGTCGATCCGTATACGGTCCGCTTCACGCTGAAGGAGCCGAACGCGCCGTTCATCCAGAACCTCGCGAT
GGAATACGCGTCGATCCTCTCCGCCGAATACGCGGACCAGCTGATGAAGGCGGGCAAGGCCGCCGACATCAATCAGAAGC
CGATCGGCACGGGCCCGTTCATCTTCCGCAGCTACACGAAGGACGCGACGATCCGCTTCGACGGCAATCCTGATTATTGG
AAGAAGGGCGCGGTGAAGATCTCGAAGCTGATCTTCTCGATCACGCCCGATCCGGGCGTGCGCGTGCAGAAGATCAAGCG
CAACGAGTGCCAGGTGATGAGCTATCCGCGGCCCGCCGACATCGCGACGCTGAAGGCCGATCCGAACGTCGACATGCCGT
CGCTGCCGGGCTTCAACCTCGGCTACCTCGCGTACAACGTGCAGCACAAGCCGGTCGACAAGCTCGAGGTGCGCCAGGCG
CTCGACATGGCGATCAACAAGAAGGCGATCCTCGAATCCGTCTATCAGGGCGCGGGGCAGGCGGCGAGCGCGCCGATGCC
GCCGACCCAATGGTCGTACGACAAGAACCTGAAGGCCGCCGCCTACGATCCGGCGAAGGCGAAGGCGCTGCTCGCGAAGG
CGGGCTACCCGAACGGCTTCCCGATCACACTGTGGGCGATGCCCGTGCAGCGCCCGTACAACCCGAACGCGAAGCTGATG
GCCGAGATGATCCAGGCCGACTGGGCGAAGATCGGCGTGCAGGCGAAGATCGTCACGTACGAGTGGGGCGAGTACATCAA
GCGCGCGCATGCGGGCGAGCACGACACGATGCTGATCGGCTGGAACGGCGACAACGGCGACCCCGACAACTGGCTCGGCA
CGCTGCTCGGCTGCGAGGCGGTCAAGGGCAACAACTTCTCCGAGTGGTGCTACAAGCCGTTCGACGAGCTGATCCAGAAG
GGCCGCGTGACGACCTCGCAGGATGCCCGCGCGAAGATTTACATGCAGGCGCAGCAGATCTTCGCGCAACAACTGCCGTT
TTCGCCGATCGCGAACTCGACCGTCTATCAGCCGGTGCGCAAGAACGTCGTCGACATGCGGATCGAGCCGCTCGGCTATG
CGCGCTTCGACGGCGTCAGCGTGAAATAA

Upstream 100 bases:

>100_bases
ACGGACGGTTTTTTCTCCAGCTTGTTCCTCTTACGAAAGCTCAAGTAATATCCGCCTACGCTGGCCTAGGCCGGCCTTGA
ACTGGAGACCTGGAGGAAAC

Downstream 100 bases:

>100_bases
GCGCGTCGGTGCGCCGTTAGCCCGACTGCACGATAATCACCCGGCGACGGGGGGCCACGAGCTCCTCGTCGCCGGTCGCA
CATTTCCCACAAGAAATTAT

Product: dipeptide ABC transporter periplasmic didpeptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MEHNRLLRALRVTAIAGVAAASFGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTASTFPIYNRLVEFERGGTK
VEPGLAEKWDISPDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVAFTFERMIDPNQPFRKAYPVSFPYFTDMGLDKLIV
KIEKVDPYTVRFTLKEPNAPFIQNLAMEYASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADPNVDMPSLPGFNLGYLAYNVQHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAAAYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLM
AEMIQADWAKIGVQAKIVTYEWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
GRVTTSQDARAKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK

Sequences:

>Translated_542_residues
MEHNRLLRALRVTAIAGVAAASFGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTASTFPIYNRLVEFERGGTK
VEPGLAEKWDISPDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVAFTFERMIDPNQPFRKAYPVSFPYFTDMGLDKLIV
KIEKVDPYTVRFTLKEPNAPFIQNLAMEYASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADPNVDMPSLPGFNLGYLAYNVQHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAAAYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLM
AEMIQADWAKIGVQAKIVTYEWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
GRVTTSQDARAKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK
>Mature_542_residues
MEHNRLLRALRVTAIAGVAAASFGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTASTFPIYNRLVEFERGGTK
VEPGLAEKWDISPDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVAFTFERMIDPNQPFRKAYPVSFPYFTDMGLDKLIV
KIEKVDPYTVRFTLKEPNAPFIQNLAMEYASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADPNVDMPSLPGFNLGYLAYNVQHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAAAYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLM
AEMIQADWAKIGVQAKIVTYEWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
GRVTTSQDARAKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=519, Percent_Identity=55.8766859344894, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1787551, Length=533, Percent_Identity=34.3339587242026, Blast_Score=334, Evalue=8e-93,
Organism=Escherichia coli, GI1787052, Length=459, Percent_Identity=28.322440087146, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1787762, Length=498, Percent_Identity=26.1044176706827, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789887, Length=467, Percent_Identity=28.6937901498929, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787495, Length=452, Percent_Identity=23.8938053097345, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1789397, Length=502, Percent_Identity=23.3067729083665, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87081878, Length=559, Percent_Identity=23.4347048300537, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60462; Mature: 60462

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHNRLLRALRVTAIAGVAAASFGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDF
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCC
TASTFPIYNRLVEFERGGTKVEPGLAEKWDISPDGKVYTFHLRHGVKFHTTDFFKPTREF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHCC
NADDVAFTFERMIDPNQPFRKAYPVSFPYFTDMGLDKLIVKIEKVDPYTVRFTLKEPNAP
CCCHHHHHHHHHCCCCCCHHHCCCCCCCCHHHCCHHEEEEEEECCCCEEEEEEEECCCCH
FIQNLAMEYASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCHH
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADPNVDMPSLPGFNL
HHHHHEEEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVQHKPVDKLEVRQALDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
AYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLMAEMIQADWAKIGVQAKIVTY
CCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEE
EWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
HHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHC
GRVTTSQDARAKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHEEECCCCCEECCCCC
VK
CC
>Mature Secondary Structure
MEHNRLLRALRVTAIAGVAAASFGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDF
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCC
TASTFPIYNRLVEFERGGTKVEPGLAEKWDISPDGKVYTFHLRHGVKFHTTDFFKPTREF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHCC
NADDVAFTFERMIDPNQPFRKAYPVSFPYFTDMGLDKLIVKIEKVDPYTVRFTLKEPNAP
CCCHHHHHHHHHCCCCCCHHHCCCCCCCCHHHCCHHEEEEEEECCCCEEEEEEEECCCCH
FIQNLAMEYASILSAEYADQLMKAGKAADINQKPIGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCHH
KKGAVKISKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADPNVDMPSLPGFNL
HHHHHEEEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVQHKPVDKLEVRQALDMAINKKAILESVYQGAGQAASAPMPPTQWSYDKNLKAA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
AYDPAKAKALLAKAGYPNGFPITLWAMPVQRPYNPNAKLMAEMIQADWAKIGVQAKIVTY
CCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEE
EWGEYIKRAHAGEHDTMLIGWNGDNGDPDNWLGTLLGCEAVKGNNFSEWCYKPFDELIQK
HHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHC
GRVTTSQDARAKIYMQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHEEECCCCCEECCCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]