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The map label for this gene is purP [H]

Identifier: 83721228

GI number: 83721228

Start: 1812798

End: 1814174

Strand: Reverse

Name: purP [H]

Synonym: BTH_I1611

Alternate gene names: 83721228

Gene position: 1814174-1812798 (Counterclockwise)

Preceding gene: 83721046

Following gene: 83720321

Centisome position: 47.63

GC content: 67.47

Gene sequence:

>1377_bases
ATGGACCTCTACCAAGGCACCGCCGCGCCTGCTGAGCGCTCGGCGCTCGAGCGCCACTTCGGCATCCGCGAGTCCGGCTC
GCGGCTGCGCACCGAGATCGTCGCCGGCGTGACGACGTTCCTGACCGCGATGTACATCATCGTCGTGAATCCCGGCATCC
TGTCGCAGGCGGGCGTGCCGTTTTCGGCCGCGCTGACGGCAACGGTGATCGTCAGCTTCCTCGGCAGCTGCGCGATGGGC
CTGTACGCGCGCAACCCGGTGCTCGTCGCGCCGGGCATGGGGATGAACGCGCTCTTCACGTTCGTGATGGTCCACGGCGG
CAAGATGCCCTGGCAGACCGCGCTCGGCTGCGTGTTCTGGGCGGGCGTGCTGTTCGCGACGCTCGCCGCGTTCAACGCGC
GCAAGCTCGTCGTCGACGCGATTCCGGCGAACCTGCGGCACGCGGTGTCGTGCGGCATCGGCCTGTTCATCAGCCTGATC
GGTCTCGTGAACGCGAAGTTCATCGTCGGCGATCCGGTGACGATCGTCCACGCGACGTCGCTCAACCCTGTGATCGTCAC
GTTTCTCGCCGGCCTCGCGATCACGACCGTGCTCGTCGTGCGCCGCGTCACGGGCGCGCTGATGCTCGGCATCGTCGCGA
CGACGCTGCTCGCGATCCCGATCGGCCGCGTGTGGGGCGACGGCAGCGCGTACTGGCCCGCCGCGATCGCAACGAAGACG
CTCGTCAACTGGAACGGCTTCGTCGCCGCGCCGGACTTCTCGGCGATCGGTCAGCTCGATCTGCTCGGCTCGCTGAAGTT
CGCGTACTGGCCGTTCATCTTCGTGATGCTGTTCACCGCGTTCTTCGACGCGCTGTCGACGTTCATGGCGATTTCGGAGG
CCGGCGACCTGCGCGACGGCGACGGCAATCCGCGCAACATCCGCCAGTCGATGATCGTCGACGCGTTCTCGGCCGTCGTG
TCCGCGCCGCTCGGCACGAGCCCCGCGAACGCGTACATCGAATCGGCGGCGGGCATCTCGGCGGGCGGGCGCACGGGGCT
CGTCGCGGTGGTCGCGGGCTTGTGCTTCGTGCCGTTCCTGTTCCTGTCGCCGCTGCTCTCGCTCGTCCCGGCGATTGCGA
CGGCGCCCGCGCTCGTGCTCGTCGGCGTGTTCATGATGGAATCGATCACGAAGATCGAATGGCACCGCTTCGACGAGGCG
ATCCCCGCGTTTCTCGCGATGATCCTGATCCCGCTCACGTACTCGATCACCGAAGGCATCGCATACGGCTTTCTGGCATT
CGTCGTGCTGAAGCTCTTCACCGGACGCCGCCGCGACGTGAAGCCCGCGATGTGGGTCGTGGCGGCGCTGTCGGTGCTAC
TCGTCGCGCAGCTCTGA

Upstream 100 bases:

>100_bases
CCTGACGGCCGCACGACGCGCGCGCCGCATGCGGCGGCGCGCGAAGCGCGCGCGTCCAGACGCGACGCGTTCGACACGAG
ACACTGAGGAGAGCTTAACG

Downstream 100 bases:

>100_bases
TTTCAATCGATACGGATTCCAAACGATGACCCAAACCGCTTTCCGCGCCCGCCTGCTGAGGTTCGACGGCGACCCCGCGC
AATCGGACGACGCGATCGCG

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MDLYQGTAAPAERSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFSAALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFWAGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLI
GLVNAKFIVGDPVTIVHATSLNPVIVTFLAGLAITTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
LVNWNGFVAAPDFSAIGQLDLLGSLKFAYWPFIFVMLFTAFFDALSTFMAISEAGDLRDGDGNPRNIRQSMIVDAFSAVV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFLFLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEA
IPAFLAMILIPLTYSITEGIAYGFLAFVVLKLFTGRRRDVKPAMWVVAALSVLLVAQL

Sequences:

>Translated_458_residues
MDLYQGTAAPAERSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFSAALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFWAGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLI
GLVNAKFIVGDPVTIVHATSLNPVIVTFLAGLAITTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
LVNWNGFVAAPDFSAIGQLDLLGSLKFAYWPFIFVMLFTAFFDALSTFMAISEAGDLRDGDGNPRNIRQSMIVDAFSAVV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFLFLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEA
IPAFLAMILIPLTYSITEGIAYGFLAFVVLKLFTGRRRDVKPAMWVVAALSVLLVAQL
>Mature_458_residues
MDLYQGTAAPAERSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFSAALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFWAGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLI
GLVNAKFIVGDPVTIVHATSLNPVIVTFLAGLAITTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
LVNWNGFVAAPDFSAIGQLDLLGSLKFAYWPFIFVMLFTAFFDALSTFMAISEAGDLRDGDGNPRNIRQSMIVDAFSAVV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFLFLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEA
IPAFLAMILIPLTYSITEGIAYGFLAFVVLKLFTGRRRDVKPAMWVVAALSVLLVAQL

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=453, Percent_Identity=40.1766004415011, Blast_Score=317, Evalue=8e-88,
Organism=Escherichia coli, GI87082309, Length=441, Percent_Identity=39.4557823129252, Blast_Score=302, Evalue=4e-83,
Organism=Escherichia coli, GI1790499, Length=448, Percent_Identity=36.1607142857143, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI48994909, Length=443, Percent_Identity=35.8916478555305, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48395; Mature: 48395

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYQGTAAPAERSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVP
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCC
FSAALTATVIVSFLGSCAMGLYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFW
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLIGLVNAKFIVGDPVTIVHATS
HHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECC
LNPVIVTFLAGLAITTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LVNWNGFVAAPDFSAIGQLDLLGSLKFAYWPFIFVMLFTAFFDALSTFMAISEAGDLRDG
HCCCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGNPRNIRQSMIVDAFSAVVSAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEAIPAFLAMILIPLTYSITEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGFLAFVVLKLFTGRRRDVKPAMWVVAALSVLLVAQL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLYQGTAAPAERSALERHFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVP
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCC
FSAALTATVIVSFLGSCAMGLYARNPVLVAPGMGMNALFTFVMVHGGKMPWQTALGCVFW
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AGVLFATLAAFNARKLVVDAIPANLRHAVSCGIGLFISLIGLVNAKFIVGDPVTIVHATS
HHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECC
LNPVIVTFLAGLAITTVLVVRRVTGALMLGIVATTLLAIPIGRVWGDGSAYWPAAIATKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LVNWNGFVAAPDFSAIGQLDLLGSLKFAYWPFIFVMLFTAFFDALSTFMAISEAGDLRDG
HCCCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGNPRNIRQSMIVDAFSAVVSAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFVPFL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FLSPLLSLVPAIATAPALVLVGVFMMESITKIEWHRFDEAIPAFLAMILIPLTYSITEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGFLAFVVLKLFTGRRRDVKPAMWVVAALSVLLVAQL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]