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The map label for this gene is mco [H]

Identifier: 83720936

GI number: 83720936

Start: 874485

End: 876224

Strand: Direct

Name: mco [H]

Synonym: BTH_I0760

Alternate gene names: 83720936

Gene position: 874485-876224 (Clockwise)

Preceding gene: 83721398

Following gene: 83721401

Centisome position: 22.96

GC content: 70.17

Gene sequence:

>1740_bases
ATGTCGAGCGACACCCCGGCGGGCCGCGTGCCCGCCGGGGTGTTTCGTTTTGGTGCGGCGCGCGCATCGTTTGCAAGTAG
TGCGCAGCGTGTGCCGGCTGGTGTATCGTCGAAACCTCCGTTTCGGCGACACAGGAATCGATCGATGTTGCGCAGACATT
TTCTTTCGAGCGCGCTGGCGGCCGCCGCCGCGTCGCTCTTCGCGCGCGGCGCGCTCGCCGCGGGCCATGCGATGGACGGC
ATGCAAGGGATGGACGGGATGGACGACATGCCCGACATGTCGCCCGCGCCTGCGCGCGCACGGCACGCGAAGCCGACGGC
GCCCGCGCTCGCGGCCGCCGACGCGTTGCCCGCGGGCGCGCCGCTCGCCGCGCTGCGCGTGCTCGCGAACGAAAGCCGCG
AGCCGGGCATGTTCCGTGCGACGCTCGTCGCGCAGCCCGTCCGGCGCGCGCTTCTGCCGGGCGCCGCGCCGACGGTGTTC
TGGCAGTTCGGCGCGGGCGCGCAAGGGCCCGCAGTCGGCCCGCTCATCGACGTGCGCGAAGGCGATACGGTCGAGATTCG
CTTCGTCAACCGGCTGCCGCAACCGTCGACGATCCACTGGCATGGGCTGCCCGTGCCGCCCGACCAGGACGGCAATCCGT
CCGATCTCGTCGCGCCGGGCGCGACGCGCGTCTATCGCTTCACGCTGCCGAAAGGAAGCGCGGGCACGTACTGGTATCAC
CCGCATCCGCACATGGCGACGGCCGAGCAGGTGTTTCGCGGACTCGCGGGGCCGTTCGTCGTGCGCGCGGCCGACGATCC
GCTCGCCGGCTGGCCCGAGCGGCATCTGTTCGTGTCCGATCTGAAGCTTGCACGCGACGGCACGATTGCGCCGAACGACA
TGATGGACTGGATGAACGGCCGCCAAGGTCAGTTCGTGCTCGTCAACGGTGCGCGGCGGCCGCGCATCGCGCTCACCGGC
GACGAACGCTGGCGCGTGTGGAACGCGTGCAGCGCGCGCTATTTGCGCATCGCGTTTGACGACGGAAGAGCATTTGCGCA
CATCGGCACCGACGGCGGCTTGTTCGAGGCGCCGCGTGACGTGACGTCGCTGCTGCTCGCGCCGGGCGAGCGCGCCGAGA
TCGTCGCACGCGCGGGCGACCGCGCGTCGCGCGCGGTGCTGACGGCGCTCGAGTACGACCGCGGCAAGATGGCGATGTCG
GACGCCGCGCACGGCAGCCTGCCGCCCGATCCCGCGATGCCGCTTGCCGACGTCGCATTCGAGTCCGCCGCGCCGCGCGC
GCTGCCTGACCGGCTGCGCGCGGTGCCCGCGCTCGGCGAGCCGGTCGCGCACAAGGAAGTCGCATTCGGCGAGCAGATGG
ACAGGAACGCGATGATGCGCGCGGACGCGCGGGGCCGACCGGCCGGCATGCGATTCATGGTGAACGGCGCGACGTTCGAG
CCGCATCGCGCGACATTGACGAGCCGGCGCGGCGACGTCGAATCGTGGACGATTCGCAACGAAACCGACATGGACCATCC
GTTCCATCTGCACGGCACGCAATTCCAGGTCGTCGAGCGCGAGATCGGCGGCAAGACGACGCCGGAGCCCTATCGCGCGT
GGCGGGACACGGTGAACGTTCGGAAGGGCGAGCGCGTGCGGATTCTCACGACGCAGACCGAGCGCGGCGAGCGAATGTTT
CACTGCCACATCCTCGAGCACGAGGATCTCGGGATGATGGGAACGCTGAAAGTCGTTTGA

Upstream 100 bases:

>100_bases
ACGACTTCGCGCGCCTGATGGAAGGCGCGACGCAAGTGTCGTGCTCGGGCTTCGGTCAGGTGCTGATCGAAAACATGCAG
TAAGCGCGTCGGCGTAGCCG

Downstream 100 bases:

>100_bases
AATGGGCGGCGGCCGAGTTCCGTGGTGGAGCGCATGGTTGTTCGCCGCGGCACTCGGGCGAAAAAAAACCCGGCTGGAAG
CCGGGTTTTCTATTTCTGAT

Product: mulitcopper oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSSDTPAGRVPAGVFRFGAARASFASSAQRVPAGVSSKPPFRRHRNRSMLRRHFLSSALAAAAASLFARGALAAGHAMDG
MQGMDGMDDMPDMSPAPARARHAKPTAPALAAADALPAGAPLAALRVLANESREPGMFRATLVAQPVRRALLPGAAPTVF
WQFGAGAQGPAVGPLIDVREGDTVEIRFVNRLPQPSTIHWHGLPVPPDQDGNPSDLVAPGATRVYRFTLPKGSAGTYWYH
PHPHMATAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDGTIAPNDMMDWMNGRQGQFVLVNGARRPRIALTG
DERWRVWNACSARYLRIAFDDGRAFAHIGTDGGLFEAPRDVTSLLLAPGERAEIVARAGDRASRAVLTALEYDRGKMAMS
DAAHGSLPPDPAMPLADVAFESAAPRALPDRLRAVPALGEPVAHKEVAFGEQMDRNAMMRADARGRPAGMRFMVNGATFE
PHRATLTSRRGDVESWTIRNETDMDHPFHLHGTQFQVVEREIGGKTTPEPYRAWRDTVNVRKGERVRILTTQTERGERMF
HCHILEHEDLGMMGTLKVV

Sequences:

>Translated_579_residues
MSSDTPAGRVPAGVFRFGAARASFASSAQRVPAGVSSKPPFRRHRNRSMLRRHFLSSALAAAAASLFARGALAAGHAMDG
MQGMDGMDDMPDMSPAPARARHAKPTAPALAAADALPAGAPLAALRVLANESREPGMFRATLVAQPVRRALLPGAAPTVF
WQFGAGAQGPAVGPLIDVREGDTVEIRFVNRLPQPSTIHWHGLPVPPDQDGNPSDLVAPGATRVYRFTLPKGSAGTYWYH
PHPHMATAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDGTIAPNDMMDWMNGRQGQFVLVNGARRPRIALTG
DERWRVWNACSARYLRIAFDDGRAFAHIGTDGGLFEAPRDVTSLLLAPGERAEIVARAGDRASRAVLTALEYDRGKMAMS
DAAHGSLPPDPAMPLADVAFESAAPRALPDRLRAVPALGEPVAHKEVAFGEQMDRNAMMRADARGRPAGMRFMVNGATFE
PHRATLTSRRGDVESWTIRNETDMDHPFHLHGTQFQVVEREIGGKTTPEPYRAWRDTVNVRKGERVRILTTQTERGERMF
HCHILEHEDLGMMGTLKVV
>Mature_578_residues
SSDTPAGRVPAGVFRFGAARASFASSAQRVPAGVSSKPPFRRHRNRSMLRRHFLSSALAAAAASLFARGALAAGHAMDGM
QGMDGMDDMPDMSPAPARARHAKPTAPALAAADALPAGAPLAALRVLANESREPGMFRATLVAQPVRRALLPGAAPTVFW
QFGAGAQGPAVGPLIDVREGDTVEIRFVNRLPQPSTIHWHGLPVPPDQDGNPSDLVAPGATRVYRFTLPKGSAGTYWYHP
HPHMATAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDGTIAPNDMMDWMNGRQGQFVLVNGARRPRIALTGD
ERWRVWNACSARYLRIAFDDGRAFAHIGTDGGLFEAPRDVTSLLLAPGERAEIVARAGDRASRAVLTALEYDRGKMAMSD
AAHGSLPPDPAMPLADVAFESAAPRALPDRLRAVPALGEPVAHKEVAFGEQMDRNAMMRADARGRPAGMRFMVNGATFEP
HRATLTSRRGDVESWTIRNETDMDHPFHLHGTQFQVVEREIGGKTTPEPYRAWRDTVNVRKGERVRILTTQTERGERMFH
CHILEHEDLGMMGTLKVV

Specific function: May be involved in copper homeostasis and oxidative stress response [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=458, Percent_Identity=32.3144104803493, Blast_Score=189, Evalue=6e-49,
Organism=Escherichia coli, GI1789394, Length=456, Percent_Identity=28.0701754385965, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR002355
- InterPro:   IPR008972 [H]

Pfam domain/function: PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 62907; Mature: 62776

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDTPAGRVPAGVFRFGAARASFASSAQRVPAGVSSKPPFRRHRNRSMLRRHFLSSALA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAAASLFARGALAAGHAMDGMQGMDGMDDMPDMSPAPARARHAKPTAPALAAADALPAGA
HHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHCCCCCC
PLAALRVLANESREPGMFRATLVAQPVRRALLPGAAPTVFWQFGAGAQGPAVGPLIDVRE
HHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEECCC
GDTVEIRFVNRLPQPSTIHWHGLPVPPDQDGNPSDLVAPGATRVYRFTLPKGSAGTYWYH
CCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCEEEC
PHPHMATAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDGTIAPNDMMDWMNG
CCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEHHHHHHHCCCCCCCHHHHHHHCC
RQGQFVLVNGARRPRIALTGDERWRVWNACSARYLRIAFDDGRAFAHIGTDGGLFEAPRD
CCCCEEEEECCCCCEEEECCCCCEEEECCCCCEEEEEEEECCCEEEEECCCCCCCCCCHH
VTSLLLAPGERAEIVARAGDRASRAVLTALEYDRGKMAMSDAAHGSLPPDPAMPLADVAF
HHHHHHCCCCCHHHEECCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHH
ESAAPRALPDRLRAVPALGEPVAHKEVAFGEQMDRNAMMRADARGRPAGMRFMVNGATFE
HCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEECCCCC
PHRATLTSRRGDVESWTIRNETDMDHPFHLHGTQFQVVEREIGGKTTPEPYRAWRDTVNV
CHHHHHHCCCCCCCEEEECCCCCCCCCEEECCCEEEEHHHHHCCCCCCHHHHHHHHHCCC
RKGERVRILTTQTERGERMFHCHILEHEDLGMMGTLKVV
CCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure 
SSDTPAGRVPAGVFRFGAARASFASSAQRVPAGVSSKPPFRRHRNRSMLRRHFLSSALA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAAASLFARGALAAGHAMDGMQGMDGMDDMPDMSPAPARARHAKPTAPALAAADALPAGA
HHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHCCCCCC
PLAALRVLANESREPGMFRATLVAQPVRRALLPGAAPTVFWQFGAGAQGPAVGPLIDVRE
HHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEECCC
GDTVEIRFVNRLPQPSTIHWHGLPVPPDQDGNPSDLVAPGATRVYRFTLPKGSAGTYWYH
CCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCEEEC
PHPHMATAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDGTIAPNDMMDWMNG
CCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEHHHHHHHCCCCCCCHHHHHHHCC
RQGQFVLVNGARRPRIALTGDERWRVWNACSARYLRIAFDDGRAFAHIGTDGGLFEAPRD
CCCCEEEEECCCCCEEEECCCCCEEEECCCCCEEEEEEEECCCEEEEECCCCCCCCCCHH
VTSLLLAPGERAEIVARAGDRASRAVLTALEYDRGKMAMSDAAHGSLPPDPAMPLADVAF
HHHHHHCCCCCHHHEECCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHH
ESAAPRALPDRLRAVPALGEPVAHKEVAFGEQMDRNAMMRADARGRPAGMRFMVNGATFE
HCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEECCCCC
PHRATLTSRRGDVESWTIRNETDMDHPFHLHGTQFQVVEREIGGKTTPEPYRAWRDTVNV
CHHHHHHCCCCCCCEEEECCCCCCCCCEEECCCEEEEHHHHHCCCCCCHHHHHHHHHCCC
RKGERVRILTTQTERGERMFHCHILEHEDLGMMGTLKVV
CCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA