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The map label for this gene is nadA [H]

Identifier: 83720822

GI number: 83720822

Start: 894262

End: 895398

Strand: Direct

Name: nadA [H]

Synonym: BTH_I0776

Alternate gene names: 83720822

Gene position: 894262-895398 (Clockwise)

Preceding gene: 83720976

Following gene: 83718617

Centisome position: 23.48

GC content: 68.16

Gene sequence:

>1137_bases
ATGCAATCGGCGATCAAACCCGTCGAGTACGACCGCCCGCTCGCGGCAGGGGCGGCCTGCGGCGTGGGCGAGGCGTGGGC
GAAGGTGCCCGCGCCGCTCGCTGCCGGCGAGCGCGAGGCGCTGAAGGCGCGGATCAAGGCGTTGCTCGAACGCGAGAAGG
CCGTGCTGGTCGCGCACTATTACGTCGACGCGGAGCTGCAGGAACTCGCGGACGAGACGGGCGGCTGCGTTGCCGATTCG
CTGGAGATGGCCCGCTTCGGGCGCGACCACGGCGCGCAGACGCTCGTGGTCGCCGGCGTGCGTTTCATGGGCGAGACGGC
GAAGATCCTGAGCCCGGGCAAGCGCGTGCTGATGCCCGACCTCGACGCGACGTGCTCGCTCGATCTCGGTTGCCCGGTCG
ACGAGTTTTCCCGGTTTTGCGACGCGCATCCGGACCGTACGGTCGTCGTCTACGCGAACACGAGCGCCGCGGTGAAGGCG
CGCGCCGACTGGATGGTCACGTCGTCGATCGGCCTTGAGATCGTCGCCAATCTGCACGCGCGCGGCGAGAAGATCATCTG
GGCGCCGGACCGCCACCTCGGCGGCTACATCCAGAAGAAGACGGGCGCGGACATGCTGATGTGGCAGGGCTCGTGTCTCG
TGCACGACGAGTTCAAGGGCATCGAGCTCGACTTGCTGCGCAACGAATACCCGGATGCGAAGATCCTCGTGCACCCGGAA
TCGCCGGAGGGCGTCGTCGCGCTCGCGGACGTCGTCGGCTCGACGACGCAGTTGATCGATGCGGCCGTGAAGCTCGACGC
TCAGCGATTCATCGTCGCGACCGATCTCGGCATCCTGCACAAGATGCGGCTCGCGGCGCCCGGCAAGACCTTCATCGAGG
CGCCGACGGCCGGCAACAGCGCGACGTGCAAGAGCTGCGCGCACTGCCCGTGGATGGCGATGAACGTGCTGTCGAACCTC
GCCGACGTGCTCGAGCGCGGTCACAACGAGATCTTCGTCGATGCGGCGATCGCCGAGCGCGCGCGCGTGCCGATCGACCG
GATGCTCGATTTCGCCGCGCGCCACAAGCAGCGCGTGCAGGCGAGCGGCGATCTGCTGCGCGATCAGCAACTCTTCGCGA
ACGTGGGGGCGGCATGA

Upstream 100 bases:

>100_bases
TTTGGGCCGCCGTTTGGCGACGGCAGCCTATCGGCAGATTGAACTTTGCATGGAACCAGAGCATGCGCCAAGCGCTAACT
CCGGTCGACAGGAGATGAGG

Downstream 100 bases:

>100_bases
CGAACGGCGCGATGTCTCCGCTTTTCGCTGAAATCTCGCGCGAATACGGCGCCGCGTTCGACGCGGCGATCGCGCGCAAC
GTGGCCGATGCGCTCGCCGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQSAIKPVEYDRPLAAGAACGVGEAWAKVPAPLAAGEREALKARIKALLEREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHGAQTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCPVDEFSRFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVANLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRNEYPDAKILVHPE
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNVLSNL
ADVLERGHNEIFVDAAIAERARVPIDRMLDFAARHKQRVQASGDLLRDQQLFANVGAA

Sequences:

>Translated_378_residues
MQSAIKPVEYDRPLAAGAACGVGEAWAKVPAPLAAGEREALKARIKALLEREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHGAQTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCPVDEFSRFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVANLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRNEYPDAKILVHPE
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNVLSNL
ADVLERGHNEIFVDAAIAERARVPIDRMLDFAARHKQRVQASGDLLRDQQLFANVGAA
>Mature_378_residues
MQSAIKPVEYDRPLAAGAACGVGEAWAKVPAPLAAGEREALKARIKALLEREKAVLVAHYYVDAELQELADETGGCVADS
LEMARFGRDHGAQTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCPVDEFSRFCDAHPDRTVVVYANTSAAVKA
RADWMVTSSIGLEIVANLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRNEYPDAKILVHPE
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNVLSNL
ADVLERGHNEIFVDAAIAERARVPIDRMLDFAARHKQRVQASGDLLRDQQLFANVGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=326, Percent_Identity=65.6441717791411, Blast_Score=450, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40800; Mature: 40800

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAIKPVEYDRPLAAGAACGVGEAWAKVPAPLAAGEREALKARIKALLEREKAVLVAHY
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEE
YVDAELQELADETGGCVADSLEMARFGRDHGAQTLVVAGVRFMGETAKILSPGKRVLMPD
EECHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCHHHHHCCCCEEECCC
LDATCSLDLGCPVDEFSRFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLEIVANLHA
CCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEECCCCHHHHHHHHC
RGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRNEYPDAKILVHPE
CCCEEEECCCCCCCCEEECCCCCCEEEECCCEEEECCCCCEEEEEHHCCCCCCEEEECCC
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNS
CCCCEEEHHHHHCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCEEECCCCCCC
ATCKSCAHCPWMAMNVLSNLADVLERGHNEIFVDAAIAERARVPIDRMLDFAARHKQRVQ
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHH
ASGDLLRDQQLFANVGAA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSAIKPVEYDRPLAAGAACGVGEAWAKVPAPLAAGEREALKARIKALLEREKAVLVAHY
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEE
YVDAELQELADETGGCVADSLEMARFGRDHGAQTLVVAGVRFMGETAKILSPGKRVLMPD
EECHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCHHHHHCCCCEEECCC
LDATCSLDLGCPVDEFSRFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLEIVANLHA
CCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEECCCCHHHHHHHHC
RGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRNEYPDAKILVHPE
CCCEEEECCCCCCCCEEECCCCCCEEEECCCEEEECCCCCEEEEEHHCCCCCCEEEECCC
SPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNS
CCCCEEEHHHHHCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCEEECCCCCCC
ATCKSCAHCPWMAMNVLSNLADVLERGHNEIFVDAAIAERARVPIDRMLDFAARHKQRVQ
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHH
ASGDLLRDQQLFANVGAA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA