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The map label for this gene is ykvO [H]

Identifier: 83720751

GI number: 83720751

Start: 2967956

End: 2968678

Strand: Direct

Name: ykvO [H]

Synonym: BTH_I2606

Alternate gene names: 83720751

Gene position: 2967956-2968678 (Clockwise)

Preceding gene: 83719229

Following gene: 83719477

Centisome position: 77.92

GC content: 73.44

Gene sequence:

>723_bases
ATGCAGGTTTCTTTCAACGATCAGCGCGTTCTCGTCGTCGGCGGCAGTTCCGGGATCGGCGCCGCGGCCGCCCGCGCGTT
CGCGGCGCTCGGCGCCGACGTGACGATCGCGTCGCGCGACGCGAACAAGCTCGCCGCCGCCGCGCACGCGATCGGCGGCC
CGCGCCCGGTTCGGCAAGCGGTGCTCGACACGACGGATGCGCCCGCCGTCGACGCCTTCTTTGCCGGCACCGAGCCGTTC
GACCATGTCGTCGTGTCGGCCGCGCAAACGCCGGGCGGGCCCGTGCGCAAGTTGCCGCTCGCCGACGCGCAGGCCGCGAT
GGACAGCAAGTTCTGGGGCGCATACCGCGTCGCGCGTGCGGCGCGCGTTGCGCCGGGCGGCTCGCTCACGTTCGTGTCCG
GCTTCCTGAGCGTGCGGCCGAGCGCGAACTCGGTGCTGCAGGGCGCGATCAACGCGGCGCTCGAAGCGCTTGCGCGCGGG
CTCGCGCTCGAACTCGCGCCGGTGCGCGTGAATGCCGTGTCGCCGGGGCTCGTCGCGACGCCGCTGTGGTCGAAGCTCGA
TGACGCGTCGCGGGAGGCGATGTACGCGTCGGCGGCCGCGCGCCTGCCCGCTCGACGCGTCGGGCAGCCCGAGGATATCG
CGAATGCGATCGTCTACCTCGCGGCGACGCCTTATGCGACGGGGTCGACGGTGCTCGTCGACGGCGGCGGCGCGATCGCG
TGA

Upstream 100 bases:

>100_bases
CCCGGCACGCGCTGCACAGCCCGCTCACGCTGCGCGAGAGCGAAACCCTCTGACGGGCGGCGGCGCCGCCTTCAATCCTC
TTCGTTCAGGAGAACACACG

Downstream 100 bases:

>100_bases
GCGTCGGGCGCGGCGGCGCTCGCCTCGCGCGCGGTTCGCGCGCGGTTCGCGGTTCGCGGTTCGCGGTTCGCGGTTCGCGG
TTCGCGGTTCGCGGTTCGCG

Product: short chain dehydrogenase

Products: 2,3-Dihydroxybenzoate; H+; Nicotinamide adenine dinucleotide - reduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MQVSFNDQRVLVVGGSSGIGAAAARAFAALGADVTIASRDANKLAAAAHAIGGPRPVRQAVLDTTDAPAVDAFFAGTEPF
DHVVVSAAQTPGGPVRKLPLADAQAAMDSKFWGAYRVARAARVAPGGSLTFVSGFLSVRPSANSVLQGAINAALEALARG
LALELAPVRVNAVSPGLVATPLWSKLDDASREAMYASAAARLPARRVGQPEDIANAIVYLAATPYATGSTVLVDGGGAIA

Sequences:

>Translated_240_residues
MQVSFNDQRVLVVGGSSGIGAAAARAFAALGADVTIASRDANKLAAAAHAIGGPRPVRQAVLDTTDAPAVDAFFAGTEPF
DHVVVSAAQTPGGPVRKLPLADAQAAMDSKFWGAYRVARAARVAPGGSLTFVSGFLSVRPSANSVLQGAINAALEALARG
LALELAPVRVNAVSPGLVATPLWSKLDDASREAMYASAAARLPARRVGQPEDIANAIVYLAATPYATGSTVLVDGGGAIA
>Mature_240_residues
MQVSFNDQRVLVVGGSSGIGAAAARAFAALGADVTIASRDANKLAAAAHAIGGPRPVRQAVLDTTDAPAVDAFFAGTEPF
DHVVVSAAQTPGGPVRKLPLADAQAAMDSKFWGAYRVARAARVAPGGSLTFVSGFLSVRPSANSVLQGAINAALEALARG
LALELAPVRVNAVSPGLVATPLWSKLDDASREAMYASAAARLPARRVGQPEDIANAIVYLAATPYATGSTVLVDGGGAIA

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=26.0700389105058, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=31.1023622047244, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=28.3400809716599, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=30.4878048780488, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=29.0196078431373, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=26.4227642276423, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=30.5220883534137, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=28.5123966942149, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=27.0491803278689, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=30.2325581395349, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=29.2307692307692, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=30, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=32.3651452282158, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=28.4090909090909, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=27.1698113207547, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=26.2745098039216, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=28.7449392712551, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=29.6747967479675, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=28.4518828451883, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=28.8, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=29.9180327868852, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=29.8387096774194, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=27.4261603375527, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=29.9212598425197, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=26.7489711934156, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.3.1.28 [C]

Molecular weight: Translated: 24183; Mature: 24183

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSFNDQRVLVVGGSSGIGAAAARAFAALGADVTIASRDANKLAAAAHAIGGPRPVRQA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCHHHHHH
VLDTTDAPAVDAFFAGTEPFDHVVVSAAQTPGGPVRKLPLADAQAAMDSKFWGAYRVARA
HHCCCCCCCHHHEECCCCCHHHHEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
ARVAPGGSLTFVSGFLSVRPSANSVLQGAINAALEALARGLALELAPVRVNAVSPGLVAT
HHCCCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCEEC
PLWSKLDDASREAMYASAAARLPARRVGQPEDIANAIVYLAATPYATGSTVLVDGGGAIA
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHEEEEEECCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MQVSFNDQRVLVVGGSSGIGAAAARAFAALGADVTIASRDANKLAAAAHAIGGPRPVRQA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCHHHHHH
VLDTTDAPAVDAFFAGTEPFDHVVVSAAQTPGGPVRKLPLADAQAAMDSKFWGAYRVARA
HHCCCCCCCHHHEECCCCCHHHHEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
ARVAPGGSLTFVSGFLSVRPSANSVLQGAINAALEALARGLALELAPVRVNAVSPGLVAT
HHCCCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCEEC
PLWSKLDDASREAMYASAAARLPARRVGQPEDIANAIVYLAATPYATGSTVLVDGGGAIA
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHEEEEEECCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 5550 [C]

Specific activity: 66

Km value (mM): 0.26 {methyl-2,3-dehydro-3-hydroxybenzoate}} 0.2 {3-oxocyclohexane-1-carboxylic} 0.3 {2,3-dihydro-2,3-dihydroxybenzoate}} [C]

Substrates: 2,3-Dihydro-2,3-dihydroxybenzoate; Nicotinamide adenine dinucleotide [C]

Specific reaction: 2,3-Dihydro-2,3-dihydroxybenzoate + Nicotinamide adenine dinucleotide <==> 2,3-Dihydroxybenzoate + H+ + Nicotinamide adenine dinucleotide - reduced [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]