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The map label for this gene is phoR [H]

Identifier: 83720326

GI number: 83720326

Start: 3179031

End: 3180341

Strand: Reverse

Name: phoR [H]

Synonym: BTH_I2767

Alternate gene names: 83720326

Gene position: 3180341-3179031 (Counterclockwise)

Preceding gene: 83719375

Following gene: 83718453

Centisome position: 83.49

GC content: 66.36

Gene sequence:

>1311_bases
ATGAACATCATCTGGGCGCGCTTTCTGGTGTCGCTCGTCCTGCTCGCGCTCGTGAGCGGAATCATCGGCGCAATCGCGGG
CCCAGTGCCGGGCCTCGTCTTCGCGCTCGCGATGCTCGTCGTGCAGGGTTTCGTCAGCACCTTCCACACGCAGCGCCTCT
GGCGCCTGCTCGATGCGCCCGTCTACGGCGAAGTGCCGAGCGCGCCGGGCATCTGGGGCGAGATCTACTACCGGCTGCAC
AAGCTCGCGAAGCAGTGGCACGCGCAGGTTCGGCAGGTCGAGCAGCAGCATTCGCGTTTCATTCAGGCGATCCAGGCGTC
GCCGAACGGCGTCGCGATGCTCGACGACCGCGATCAGATCGAGTGGTGCAACGCGATCGCGGAAGTGCACTTCGGGCTCG
ACGCGAAGCGCGACCTGCGCCAGCACATCACGCATCTCGTGCGCCATCCGGATTTCGTCCGCTACCTGAACGGCCAGCAT
TACGACGAGACGCTCGTGATGCGCGGCATGGGCGGCAACCGGCAGAACGTGCTCGCCGTGCAGGTGTTTCCGTACGGGGA
GAATCGCAAGCTGCTGCTCACGCAGGACATCACCGAGCTCGAGCGCACCGATGCGATGCGGCGCGACTTCGTCGCGAACG
TCTCGCATGAGCTGAAGACGCCGCTCACCGTGCTGTCGGGCTTTCTCGAGACGATGCGCGAGCTGCCGCTGTCGGACGAC
GAGCGCGCTCGCTATCTCGAGCTGATGGAGCAGCAGGCGTCGCGGATGCGGCACATCGTCACCGATCTGCTCGTGCTCGC
GAAGCTCGAAGGCGAGAGCAAGCCGCCCGCCGATCGGGCGGTCGACATGCGCACGGTGCTCGATCATCTGAAGGACGATG
CGCAGACGCTGTCGAACGGCCATCACGAGATCACGTTCAAGGTTGACGAGACGCTCGCGGTGACGGGCGCGCAGACCGAG
ATTTTCAGCGCGCTCGGCAACCTCGTGACGAATGCGATCCGCTATACGCCTGACGGCGGGACGATTCGCGTCGAATGGCG
GCGCGACGGCGCGCAGGCTGTGTTTTCGGTCACCGACAGCGGCCTCGGCATCCCGGCCGCCGATCTGCCGCGGCTCACCG
AGCGTTTCTATCGCGTCGATCGCAGCCGCTCGCGCGACACGGGCGGCACGGGGCTCGGGCTCGCGATCGTCAAGCACGTG
CTGCAACGGCACGACGCGCAACTGTCGATCCAGAGCGAGGAAGGGCGAGGCAGCACGTTCAGCGCGCGCTTTCCCGCGCA
TCGGACGATCAGCCGGCGACACGCGGCGTGA

Upstream 100 bases:

>100_bases
CAGCGGCTACCGGCTCGCGAAACACGCGTAACGGTTGCGCGGCGCGAAGGGTCAGCGCCGCCGCGTGACATCGTTTTCCT
CTTTCGTCGGGCGCCGAATC

Downstream 100 bases:

>100_bases
TGTGAGGCGCGCGCGGCGCCGGGGATCGCCGCGCTTCTCCGTCGAGGTTTTTCGATTCGGCGGCGCACGCGCGTCGCGTT
GCCGCGTCGAACGGGCGCCG

Product: histidine protein kinase PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNIIWARFLVSLVLLALVSGIIGAIAGPVPGLVFALAMLVVQGFVSTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDRDQIEWCNAIAEVHFGLDAKRDLRQHITHLVRHPDFVRYLNGQH
YDETLVMRGMGGNRQNVLAVQVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSDD
ERARYLELMEQQASRMRHIVTDLLVLAKLEGESKPPADRAVDMRTVLDHLKDDAQTLSNGHHEITFKVDETLAVTGAQTE
IFSALGNLVTNAIRYTPDGGTIRVEWRRDGAQAVFSVTDSGLGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDAQLSIQSEEGRGSTFSARFPAHRTISRRHAA

Sequences:

>Translated_436_residues
MNIIWARFLVSLVLLALVSGIIGAIAGPVPGLVFALAMLVVQGFVSTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDRDQIEWCNAIAEVHFGLDAKRDLRQHITHLVRHPDFVRYLNGQH
YDETLVMRGMGGNRQNVLAVQVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSDD
ERARYLELMEQQASRMRHIVTDLLVLAKLEGESKPPADRAVDMRTVLDHLKDDAQTLSNGHHEITFKVDETLAVTGAQTE
IFSALGNLVTNAIRYTPDGGTIRVEWRRDGAQAVFSVTDSGLGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDAQLSIQSEEGRGSTFSARFPAHRTISRRHAA
>Mature_436_residues
MNIIWARFLVSLVLLALVSGIIGAIAGPVPGLVFALAMLVVQGFVSTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDRDQIEWCNAIAEVHFGLDAKRDLRQHITHLVRHPDFVRYLNGQH
YDETLVMRGMGGNRQNVLAVQVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSDD
ERARYLELMEQQASRMRHIVTDLLVLAKLEGESKPPADRAVDMRTVLDHLKDDAQTLSNGHHEITFKVDETLAVTGAQTE
IFSALGNLVTNAIRYTPDGGTIRVEWRRDGAQAVFSVTDSGLGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDAQLSIQSEEGRGSTFSARFPAHRTISRRHAA

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=422, Percent_Identity=37.2037914691943, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI145693157, Length=346, Percent_Identity=28.9017341040462, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=32.3404255319149, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=263, Percent_Identity=27.7566539923954, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI48994928, Length=363, Percent_Identity=26.7217630853994, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789149, Length=332, Percent_Identity=29.5180722891566, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790436, Length=302, Percent_Identity=27.4834437086093, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=32.1266968325792, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1790346, Length=215, Percent_Identity=30.6976744186047, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=29.3103448275862, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=25.5905511811024, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082128, Length=251, Percent_Identity=24.7011952191235, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787894, Length=243, Percent_Identity=27.5720164609054, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=395, Percent_Identity=21.5189873417722, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=244, Percent_Identity=31.1475409836066, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789403, Length=245, Percent_Identity=28.9795918367347, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=24.4444444444444, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788279, Length=195, Percent_Identity=25.1282051282051, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49023; Mature: 49023

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIWARFLVSLVLLALVSGIIGAIAGPVPGLVFALAMLVVQGFVSTFHTQRLWRLLDAP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGEVPSAPGIWGEIYYRLHKLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDRDQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
EWCNAIAEVHFGLDAKRDLRQHITHLVRHPDFVRYLNGQHYDETLVMRGMGGNRQNVLAV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHEEECCCCCCCCEEEE
QVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSDD
EEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
ERARYLELMEQQASRMRHIVTDLLVLAKLEGESKPPADRAVDMRTVLDHLKDDAQTLSNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HHEITFKVDETLAVTGAQTEIFSALGNLVTNAIRYTPDGGTIRVEWRRDGAQAVFSVTDS
CEEEEEEECCEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCHHHHHCCCC
GLGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDAQLSIQSEEGRGSTF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEE
SARFPAHRTISRRHAA
ECCCCCHHHHHHHCCC
>Mature Secondary Structure
MNIIWARFLVSLVLLALVSGIIGAIAGPVPGLVFALAMLVVQGFVSTFHTQRLWRLLDAP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGEVPSAPGIWGEIYYRLHKLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDRDQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
EWCNAIAEVHFGLDAKRDLRQHITHLVRHPDFVRYLNGQHYDETLVMRGMGGNRQNVLAV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHEEECCCCCCCCEEEE
QVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLSDD
EEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
ERARYLELMEQQASRMRHIVTDLLVLAKLEGESKPPADRAVDMRTVLDHLKDDAQTLSNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HHEITFKVDETLAVTGAQTEIFSALGNLVTNAIRYTPDGGTIRVEWRRDGAQAVFSVTDS
CEEEEEEECCEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCHHHHHCCCC
GLGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDAQLSIQSEEGRGSTF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEE
SARFPAHRTISRRHAA
ECCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2556368 [H]