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The map label for this gene is envZ [H]

Identifier: 83720306

GI number: 83720306

Start: 2370457

End: 2371794

Strand: Reverse

Name: envZ [H]

Synonym: BTH_I2093

Alternate gene names: 83720306

Gene position: 2371794-2370457 (Counterclockwise)

Preceding gene: 83719808

Following gene: 83720312

Centisome position: 62.26

GC content: 68.09

Gene sequence:

>1338_bases
TTGACGCTCGTGTTCGGCGGGCTGTTCTGGCGCACCTTCCTGCTGATTGCGCTGTTGATCGCAGTCAGTCTCGCCGCGTG
GTTCCAGAGCTTCCGGGTGATCGAGCGCGAGCCGCGCGCGCAGCGCGTCGCGCTGCAGCTCGTCGCGATCGTGAAGCTCA
CGCGCACTGCCCTGCTCTATTCCGATCCCGACCTGCGCCGCGCGCTGCTGCAGGACCTCGAGAGCAACGAGGGCGTGCGT
GTCTATCCGCGCGAGAAAACCGACAAGTTCAAGCTGCAGCCCGACGAGTCGCTGAACCGGCTGATCGAGCACGACATCCG
CAGCCGCCTCGGCGACGACACGGTGATCGCGCAATCGGTCAACGACATCCCCGGCGTGTGGATCAGCTTCAAGATCGACG
ACGACGACTACTGGGTCGCGCTCGACCGCGATCAGCTCGACACCGTCACCGGCCTGCAATGGGCGGGCTGGGGCCTGTTC
GCGCTCGCGCTGTCGCTCATCGGCTCGGCGTTCATCACGAGCCTCGTGAACCAGCCGTTCTCGCGGCTCGCGCTCGCCGC
GCGCAAGGTGGGCTCCGGCCAAACGCCGGAACCGCTGCCCGAGCGCGGAATGGGCGTCGCCGCCGAGACGAACCGCAGCT
TCAACCAGATGGTGCGCGATCTCGAGCAGCTCGAGGCCGATCGCGCGCTGATGCTCGCGGGCATCTCGCACGATCTGCGC
ACGCCGCTCGCGCGGCTGCGCCTCGAGACCGAGATGAGTCCGTCCGATCAGGCGACGAAGGACGCGATGGTCGACGACAT
CGAGCAGATGGACCGCATCATCGCCGCGTTCATCGATTACGCACGCCCCGCGCAGCGCACGCCGGAACCCGTCGACCTGT
CGCAGATCGCGCGCGAGGTCGCCGCGCGGATCGTCAGCGAAGACGGCGTGCAGCTCGACATTCGCCTGGCCCCCGCGGCC
GTCATCGAAGCGGACGAAACGGACATGCGCCGCGTGATCGGCAACCTCGTCGAGAACGCGCGCAAGTATGGGCAGAGCAA
GAAGGACGGCGTCGCGCGCATCTCGCTCGAAACACGGGTGACGCACGCGCGCGTCGAACTCGTCGTCACCGACGAGGGCC
CCGGCATCCCCGAGGATCAGTTGCCGCTCGTGATGCGCCCGTTCTATCGCGTCGACGCGGCGCGCAGCAAAGCCGACGGC
ACCGGGCTCGGCATGGCGATCGTGCTGCGTCTCGTGAACCGCTACCGAGGCACGCTGCGGCTTCGCAACCGCGCGCCCGG
CGCGGGTCTCGAAGTCACGCTGGAGTTTCCGAGCGCGAAAGCGCGTGCGGCTGCGTGA

Upstream 100 bases:

>100_bases
CGGCGCGGCCTGATTGCAGCCCCGACGCAATACACGTCTTCGACGCCACGCCTTTGACGCCAGTTAGACAGCCAGTCCTA
TGCGTATCGACCGGCGCCTC

Downstream 100 bases:

>100_bases
CGCACGACGAGTCCCTCCCTCGATGGTCGAACCCTATCGGCGTCTTTGAAAATTCCTATGAAGTTCGTTAGTTAAAATCT
ATTGATAGGAAAATACAATA

Product: sensor histidine kinase RisS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTLVFGGLFWRTFLLIALLIAVSLAAWFQSFRVIEREPRAQRVALQLVAIVKLTRTALLYSDPDLRRALLQDLESNEGVR
VYPREKTDKFKLQPDESLNRLIEHDIRSRLGDDTVIAQSVNDIPGVWISFKIDDDDYWVALDRDQLDTVTGLQWAGWGLF
ALALSLIGSAFITSLVNQPFSRLALAARKVGSGQTPEPLPERGMGVAAETNRSFNQMVRDLEQLEADRALMLAGISHDLR
TPLARLRLETEMSPSDQATKDAMVDDIEQMDRIIAAFIDYARPAQRTPEPVDLSQIAREVAARIVSEDGVQLDIRLAPAA
VIEADETDMRRVIGNLVENARKYGQSKKDGVARISLETRVTHARVELVVTDEGPGIPEDQLPLVMRPFYRVDAARSKADG
TGLGMAIVLRLVNRYRGTLRLRNRAPGAGLEVTLEFPSAKARAAA

Sequences:

>Translated_445_residues
MTLVFGGLFWRTFLLIALLIAVSLAAWFQSFRVIEREPRAQRVALQLVAIVKLTRTALLYSDPDLRRALLQDLESNEGVR
VYPREKTDKFKLQPDESLNRLIEHDIRSRLGDDTVIAQSVNDIPGVWISFKIDDDDYWVALDRDQLDTVTGLQWAGWGLF
ALALSLIGSAFITSLVNQPFSRLALAARKVGSGQTPEPLPERGMGVAAETNRSFNQMVRDLEQLEADRALMLAGISHDLR
TPLARLRLETEMSPSDQATKDAMVDDIEQMDRIIAAFIDYARPAQRTPEPVDLSQIAREVAARIVSEDGVQLDIRLAPAA
VIEADETDMRRVIGNLVENARKYGQSKKDGVARISLETRVTHARVELVVTDEGPGIPEDQLPLVMRPFYRVDAARSKADG
TGLGMAIVLRLVNRYRGTLRLRNRAPGAGLEVTLEFPSAKARAAA
>Mature_444_residues
TLVFGGLFWRTFLLIALLIAVSLAAWFQSFRVIEREPRAQRVALQLVAIVKLTRTALLYSDPDLRRALLQDLESNEGVRV
YPREKTDKFKLQPDESLNRLIEHDIRSRLGDDTVIAQSVNDIPGVWISFKIDDDDYWVALDRDQLDTVTGLQWAGWGLFA
LALSLIGSAFITSLVNQPFSRLALAARKVGSGQTPEPLPERGMGVAAETNRSFNQMVRDLEQLEADRALMLAGISHDLRT
PLARLRLETEMSPSDQATKDAMVDDIEQMDRIIAAFIDYARPAQRTPEPVDLSQIAREVAARIVSEDGVQLDIRLAPAAV
IEADETDMRRVIGNLVENARKYGQSKKDGVARISLETRVTHARVELVVTDEGPGIPEDQLPLVMRPFYRVDAARSKADGT
GLGMAIVLRLVNRYRGTLRLRNRAPGAGLEVTLEFPSAKARAAA

Specific function: Member of the two-component regulatory system envZ/ompR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates ompR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789808, Length=449, Percent_Identity=31.8485523385301, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1788393, Length=282, Percent_Identity=30.4964539007092, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=29.0322580645161, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787894, Length=297, Percent_Identity=28.2828282828283, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=29.4871794871795, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=29.8319327731092, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=28.8990825688073, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790551, Length=284, Percent_Identity=26.7605633802817, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=314, Percent_Identity=24.8407643312102, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=25.6756756756757, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=27.9835390946502, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=31.063829787234, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790861, Length=288, Percent_Identity=26.3888888888889, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787374, Length=229, Percent_Identity=26.2008733624454, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=28.2511210762332, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49502; Mature: 49371

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVFGGLFWRTFLLIALLIAVSLAAWFQSFRVIEREPRAQRVALQLVAIVKLTRTALLY
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
SDPDLRRALLQDLESNEGVRVYPREKTDKFKLQPDESLNRLIEHDIRSRLGDDTVIAQSV
CCHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHH
NDIPGVWISFKIDDDDYWVALDRDQLDTVTGLQWAGWGLFALALSLIGSAFITSLVNQPF
CCCCCEEEEEEECCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
SRLALAARKVGSGQTPEPLPERGMGVAAETNRSFNQMVRDLEQLEADRALMLAGISHDLR
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHH
TPLARLRLETEMSPSDQATKDAMVDDIEQMDRIIAAFIDYARPAQRTPEPVDLSQIAREV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AARIVSEDGVQLDIRLAPAAVIEADETDMRRVIGNLVENARKYGQSKKDGVARISLETRV
HHHHHCCCCCEEEEEECCHHEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHEE
THARVELVVTDEGPGIPEDQLPLVMRPFYRVDAARSKADGTGLGMAIVLRLVNRYRGTLR
EEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEE
LRNRAPGAGLEVTLEFPSAKARAAA
ECCCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TLVFGGLFWRTFLLIALLIAVSLAAWFQSFRVIEREPRAQRVALQLVAIVKLTRTALLY
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
SDPDLRRALLQDLESNEGVRVYPREKTDKFKLQPDESLNRLIEHDIRSRLGDDTVIAQSV
CCHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHH
NDIPGVWISFKIDDDDYWVALDRDQLDTVTGLQWAGWGLFALALSLIGSAFITSLVNQPF
CCCCCEEEEEEECCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
SRLALAARKVGSGQTPEPLPERGMGVAAETNRSFNQMVRDLEQLEADRALMLAGISHDLR
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHH
TPLARLRLETEMSPSDQATKDAMVDDIEQMDRIIAAFIDYARPAQRTPEPVDLSQIAREV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AARIVSEDGVQLDIRLAPAAVIEADETDMRRVIGNLVENARKYGQSKKDGVARISLETRV
HHHHHCCCCCEEEEEECCHHEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHEE
THARVELVVTDEGPGIPEDQLPLVMRPFYRVDAARSKADGTGLGMAIVLRLVNRYRGTLR
EEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEE
LRNRAPGAGLEVTLEFPSAKARAAA
ECCCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6292200; 2997120; 9278503; 8132603; 2277041; 2824492; 1323560; 9817206; 10426948 [H]