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The map label for this gene is glmU [H]

Identifier: 83720136

GI number: 83720136

Start: 323768

End: 325174

Strand: Reverse

Name: glmU [H]

Synonym: BTH_I0289

Alternate gene names: 83720136

Gene position: 325174-323768 (Counterclockwise)

Preceding gene: 83718777

Following gene: 83719848

Centisome position: 8.54

GC content: 69.37

Gene sequence:

>1407_bases
ATGCTAGAATGGCCAGCTTCGAACTCTCCCTACGAAACTGGCGCCATGAATATCGTGATTTTGGCGGCAGGCACCGGCAA
GCGCATGCGTTCGGCGCTGCCGAAAGTGCTTCATCCTCTGGCCGGCAGGCCCCTTCTCTCCCACGTGATCGACACCGCCC
GCGCGCTCGCGCCGTCCCGGCTCGTCGTCGTGATCGGCCACGGCGCCGAGCGGGTGCGCGCGGCCGTCGCCGCGCCCGAC
GTGCAGTTCGCGGTGCAGGAGCAACAGCTCGGCACGGGGCACGCGGTGCGCCAGGCGCTGCCGCTGCTCGACCCGTCGCA
GCCGACGCTCGTGCTGTACGGCGACGTGCCGCTCACGCGCGCGGCGACGCTCAGGCGCCTCGCCGACGCCGCGACCGACG
CCCGCTACGGCGTGCTGACCGTCACGCTCGACGATCCGACGGGCTACGGGCGCATCGTGCGCGACCAGGCGGGGTGCGTC
ACGCGCATCGTCGAGCAGAAGGACGCTTCGGCCGACGAGCTGAAGATCGCCGAAATCAACACGGGCATCGTCGTCGCGCC
TACCGCGCAGCTGTCGATGTGGCTCGGCGCGCTCGGCAACGACAACGCGCAGGGCGAGTACTACCTGACCGACGTCGTCG
AGCAGGCGATCGAAGCGGGCTTCGAGATCGTCACGACGCAGCCGGACGACGAATGGGAGACGCTCGGCGTCAACAGCAAG
GCGCAGCTCGCCGAGCTCGAGCGCATTCATCAGCGCAAGCTCGCCGAAGCGCTGCTTGCCGATGGCGTGACGCTCGCCGA
TCCGGCGCGCATCGACGTGCGCGGCAAGCTCACGTGCGGGCGCGACGTGTCGATCGACGTGAACTGCGTGTTCGAAGGCG
ACGTGACGCTTGCCGACGGCGTGACGATCGGCGCGAACTGCGTGATCCGCAACGCGGCGATCGCCGCGGGCGCGCGCGTC
GACGCGTTCTCGCATCTCGACGGCGCGACGCTCGGCGCGAACACGGTCGTCGGCCCGTATGCACGGCTGCGCCCGGGCGC
GGTGCTCGCCGACGACGCGCACGTCGGCAACTTCGTCGAGGTGAAGAACGCGACGCTCGGCCACGGCTCGAAGGCGAACC
ATCTGACCTATCTCGGCGACGCGGACATCGGCGCGCGCGTGAACGTCGGCGCGGGCACGATCACGTGCAACTACGACGGC
GCGAACAAGTTCCGCACGGTCATCGAGGACGACGTGTTCGTCGGCTCGGACACGCAGTTCGTCGCGCCGGTGCGCGTCGG
CCGCGGCGTGACGGTCGCGGCGGGCACGACCGTGTGGAAGGACGTGGCCGAAGGCATGCTCGTGCTCAACGACAAGACGC
AGACCGCGAAAAGCGGCTACGTGCGTCCCGTCAAGAAGAAGAGCTGA

Upstream 100 bases:

>100_bases
CGCGGCCGCGGCGGCTCGCCGGGCCCGCCGAACTCGCCCGCGCGGTGGCCGCCGCCGCGCCCGTCCGGCCCCCCGCGCAG
CCGCGCCGGACGGGGCCTGC

Downstream 100 bases:

>100_bases
ACCGTTTTTCGGGCGCGCAGCGGCGCGCCCGCGTCATTGTCGAGTTTCGAGGATAGATTTCATGTGCGGGATTGTCGGCG
CGGTTGCGCAACGTAACATC

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MLEWPASNSPYETGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAERVRAAVAAPD
VQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRAATLRRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCV
TRIVEQKDASADELKIAEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSK
AQLAELERIHQRKLAEALLADGVTLADPARIDVRGKLTCGRDVSIDVNCVFEGDVTLADGVTIGANCVIRNAAIAAGARV
DAFSHLDGATLGANTVVGPYARLRPGAVLADDAHVGNFVEVKNATLGHGSKANHLTYLGDADIGARVNVGAGTITCNYDG
ANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAGTTVWKDVAEGMLVLNDKTQTAKSGYVRPVKKKS

Sequences:

>Translated_468_residues
MLEWPASNSPYETGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAERVRAAVAAPD
VQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRAATLRRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCV
TRIVEQKDASADELKIAEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSK
AQLAELERIHQRKLAEALLADGVTLADPARIDVRGKLTCGRDVSIDVNCVFEGDVTLADGVTIGANCVIRNAAIAAGARV
DAFSHLDGATLGANTVVGPYARLRPGAVLADDAHVGNFVEVKNATLGHGSKANHLTYLGDADIGARVNVGAGTITCNYDG
ANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAGTTVWKDVAEGMLVLNDKTQTAKSGYVRPVKKKS
>Mature_468_residues
MLEWPASNSPYETGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAERVRAAVAAPD
VQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRAATLRRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCV
TRIVEQKDASADELKIAEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSK
AQLAELERIHQRKLAEALLADGVTLADPARIDVRGKLTCGRDVSIDVNCVFEGDVTLADGVTIGANCVIRNAAIAAGARV
DAFSHLDGATLGANTVVGPYARLRPGAVLADDAHVGNFVEVKNATLGHGSKANHLTYLGDADIGARVNVGAGTITCNYDG
ANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAGTTVWKDVAEGMLVLNDKTQTAKSGYVRPVKKKS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=453, Percent_Identity=55.1876379690949, Blast_Score=493, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 49347; Mature: 49347

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEWPASNSPYETGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSR
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCE
LVVVIGHGAERVRAAVAAPDVQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTR
EEEEEECCHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCCHH
AATLRRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASADELKIAEIN
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCCEEEEEEC
TGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSK
CCEEEECHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCEEEEECCCCCCHHEECCCCH
AQLAELERIHQRKLAEALLADGVTLADPARIDVRGKLTCGRDVSIDVNCVFEGDVTLADG
HHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEEEEECCCCEEEEEEEEECCEEEECC
VTIGANCVIRNAAIAAGARVDAFSHLDGATLGANTVVGPYARLRPGAVLADDAHVGNFVE
EEECCCEEEECCHHHCCCCCCHHHCCCCCCCCCCCEECCHHHCCCCEEEECCCCCCCEEE
VKNATLGHGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVGSDTQF
ECCCCCCCCCCCCEEEEECCCCCCCEEECCCEEEEEECCCCHHHHHHHCCCEEECCCCCE
VAPVRVGRGVTVAAGTTVWKDVAEGMLVLNDKTQTAKSGYVRPVKKKS
EEEEECCCCEEEEECHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLEWPASNSPYETGAMNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSR
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCE
LVVVIGHGAERVRAAVAAPDVQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTR
EEEEEECCHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCCHH
AATLRRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASADELKIAEIN
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCCEEEEEEC
TGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSK
CCEEEECHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCEEEEECCCCCCHHEECCCCH
AQLAELERIHQRKLAEALLADGVTLADPARIDVRGKLTCGRDVSIDVNCVFEGDVTLADG
HHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEEEEECCCCEEEEEEEEECCEEEECC
VTIGANCVIRNAAIAAGARVDAFSHLDGATLGANTVVGPYARLRPGAVLADDAHVGNFVE
EEECCCEEEECCHHHCCCCCCHHHCCCCCCCCCCCEECCHHHCCCCEEEECCCCCCCEEE
VKNATLGHGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVGSDTQF
ECCCCCCCCCCCCEEEEECCCCCCCEEECCCEEEEEECCCCHHHHHHHCCCEEECCCCCE
VAPVRVGRGVTVAAGTTVWKDVAEGMLVLNDKTQTAKSGYVRPVKKKS
EEEEECCCCEEEEECHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA