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The map label for this gene is glmS-1 [H]

Identifier: 83719848

GI number: 83719848

Start: 321874

End: 323706

Strand: Reverse

Name: glmS-1 [H]

Synonym: BTH_I0288

Alternate gene names: 83719848

Gene position: 323706-321874 (Counterclockwise)

Preceding gene: 83720136

Following gene: 83718643

Centisome position: 8.5

GC content: 68.25

Gene sequence:

>1833_bases
ATGTGCGGGATTGTCGGCGCGGTTGCGCAACGTAACATCGTTCCGGTGCTGATCGAAGGACTGCGCCGTCTCGAGTATCG
CGGCTACGACTCGTGCGGCGTCGCGGTGCTCGGCGCCGGCGCGCCTGCGCCGGGCGCGCCGAGGCGCGCGCGCAGCGTCG
CGCGCGTCGCCGATCTCGATGCGCAGGTGCGCGAGTCGCATCTCGGAGGCGTAACCGGCATCGCGCACACGCGCTGGGCG
ACGCACGGCGCGCCCGTCACGCACAACGCGCACCCGATCTTCTCGTCGAACGCGCTCGCGCTCGTGCACAACGGCATCAT
CGAGAACTTCGAGCCGCTGCGCGAGGGGCTGCGCGCGAAGGGCTACGCGTTCGTATCGCAGACCGACACCGAAGTCATCG
CGCACCTGATCCACAGCCTCTATCGCGGCAACCTGTTCGCGGCCGTGCAGGAAGCCGTCAAGCAGTTGCACGGCGCGTAC
GCGATCGCGGTGATCCACCAGGACGAGCCGCACACCGTCGTCGGCGCGCGCCAGGGCTCGCCGCTCGTCGTCGGCTTCGG
CGAACAAGAGAACTTCCTCGCGTCCGACGCGCTCGCGCTCGCGGGCAGCACCGATCGCTTCACGTTCCTCGAGGAAGGCG
ACGTCTGCGAGCTGACGCTCGCGGGCGTGACGATCGTCGATCGCGACGGCGCGCGCGCCGTGCGCGAGGTGCGCGTCGTC
GCCGCATACGGCGGCGCGGTCGAGCTCGGCCCGTATCGGCACTTCATGCAGAAGGAAATCTTCGAGCAGCCGCGCGCGAT
CGCCGACACGATTGCGCAAGCGGACGCGTTCGATCCGTCGCTGTTCGGCGAGCGCGCGGGCAGCGTATTCGCGGGCATCG
ACAGCCTGCTGATCCTCGCGTGCGGCACCAGCTACTACTCGGGCCTCACCGCGAAGTACTGGCTCGAATCGATCGCGAAA
ATCCCGACGCAAGTCGAGATCGCGAGCGAATACCGCTATCGCGAATCGGTGCCGAACCCGCGCGCGCTCGTCGTCGTGAT
CTCGCAGTCGGGCGAGACGGCCGATACGCTCGCCGCGCTCAAGCACGCGCAGGCGCTCGGCCACGCGCACACGCTCGCGA
TCTGCAACGTCGCGACGAGCGCGATGGTGCGCCAGACCGAGCTGCAGTTCCTCACGCACGCGGGCACCGAGATCGGCGTC
GCTTCGACGAAGGCGTTCACGACGCAGCTCGTCGCGCTGTTCGTGCTCGCGGCGACGCTCGGCAAGCTGCGCGGCCACGT
CGACGCGGCCCGCGAAGCCGATTACCTGAAGCAGTTGCGCCACCTGCCCGCCGCGCTCAACAGCGTGCTCGCGCTCGAGC
CGCAGATCATCGCGTGGTCCGAAGAGTTCGCGCGTAAGGAAAACGCGCTGTTCCTCGGCCGTGGGCTGCACTATCCGATC
TCGCTCGAAGGCGCGCTGAAGCTCAAGGAGATCTCGTACATCCACGCGGAAGCGTATCCGGCGGGCGAACTGAAGCACGG
GCCGCTCGCGCTCGTGACGGAGGCGATGCCGGTCGTCACCGTCGCGCCGAACGACACGCTGCTCGAGAAGCTGAAATCGA
ACATGCAGGAAGTGCGCGCGCGCGGCGGCGAGCTGTACGTGTTCGCCGACGCGGACACGCACATCGTCAACGACGAAGGG
CTGCACGTGATCCGGATGCCCGAGCATTACGGGCCGCTGTCGCCGATCCTGCACGTCGTGCCGCTGCAGTTGCTCGCGTA
TCACACCGCGTGCGCGCGCGGCACCGACGTCGACAAGCCGCGCAATCTCGCGAAATCCGTGACGGTGGAGTAA

Upstream 100 bases:

>100_bases
AAAAGCGGCTACGTGCGTCCCGTCAAGAAGAAGAGCTGAACCGTTTTTCGGGCGCGCAGCGGCGCGCCCGCGTCATTGTC
GAGTTTCGAGGATAGATTTC

Downstream 100 bases:

>100_bases
AGCGCGCGCGACGGAACACGCGATCCGCGCCCCCCCGCGGATCGCTCGCCTCCCCCGCTGCGATCCTCCCGCCTCAAGCC
CTGACGAACGTATCGGCACC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGAGAPAPGAPRRARSVARVADLDAQVRESHLGGVTGIAHTRWA
THGAPVTHNAHPIFSSNALALVHNGIIENFEPLREGLRAKGYAFVSQTDTEVIAHLIHSLYRGNLFAAVQEAVKQLHGAY
AIAVIHQDEPHTVVGARQGSPLVVGFGEQENFLASDALALAGSTDRFTFLEEGDVCELTLAGVTIVDRDGARAVREVRVV
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQADAFDPSLFGERAGSVFAGIDSLLILACGTSYYSGLTAKYWLESIAK
IPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAALKHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGV
ASTKAFTTQLVALFVLAATLGKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPI
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEG
LHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_610_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGAGAPAPGAPRRARSVARVADLDAQVRESHLGGVTGIAHTRWA
THGAPVTHNAHPIFSSNALALVHNGIIENFEPLREGLRAKGYAFVSQTDTEVIAHLIHSLYRGNLFAAVQEAVKQLHGAY
AIAVIHQDEPHTVVGARQGSPLVVGFGEQENFLASDALALAGSTDRFTFLEEGDVCELTLAGVTIVDRDGARAVREVRVV
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQADAFDPSLFGERAGSVFAGIDSLLILACGTSYYSGLTAKYWLESIAK
IPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAALKHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGV
ASTKAFTTQLVALFVLAATLGKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPI
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEG
LHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE
>Mature_610_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGAGAPAPGAPRRARSVARVADLDAQVRESHLGGVTGIAHTRWA
THGAPVTHNAHPIFSSNALALVHNGIIENFEPLREGLRAKGYAFVSQTDTEVIAHLIHSLYRGNLFAAVQEAVKQLHGAY
AIAVIHQDEPHTVVGARQGSPLVVGFGEQENFLASDALALAGSTDRFTFLEEGDVCELTLAGVTIVDRDGARAVREVRVV
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQADAFDPSLFGERAGSVFAGIDSLLILACGTSYYSGLTAKYWLESIAK
IPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAALKHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGV
ASTKAFTTQLVALFVLAATLGKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPI
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEG
LHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=686, Percent_Identity=36.1516034985423, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI4826742, Length=691, Percent_Identity=35.3111432706223, Blast_Score=376, Evalue=1e-104,
Organism=Escherichia coli, GI1790167, Length=616, Percent_Identity=55.6818181818182, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI87082251, Length=322, Percent_Identity=23.2919254658385, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788651, Length=233, Percent_Identity=28.3261802575107, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17539970, Length=439, Percent_Identity=39.1799544419134, Blast_Score=282, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17532899, Length=438, Percent_Identity=38.1278538812785, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17532897, Length=438, Percent_Identity=38.1278538812785, Blast_Score=276, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322745, Length=449, Percent_Identity=36.9710467706013, Blast_Score=262, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6323731, Length=439, Percent_Identity=28.9293849658314, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=37.2549019607843, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323958, Length=295, Percent_Identity=25.0847457627119, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357745, Length=691, Percent_Identity=35.0217076700434, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI28573187, Length=257, Percent_Identity=26.0700389105058, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65612; Mature: 65612

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGAGAPAPGAPRRARSVARVADLD
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
AQVRESHLGGVTGIAHTRWATHGAPVTHNAHPIFSSNALALVHNGIIENFEPLREGLRAK
HHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHC
GYAFVSQTDTEVIAHLIHSLYRGNLFAAVQEAVKQLHGAYAIAVIHQDEPHTVVGARQGS
CEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
PLVVGFGEQENFLASDALALAGSTDRFTFLEEGDVCELTLAGVTIVDRDGARAVREVRVV
CEEEECCCCCCCHHHHHHHCCCCCCCEEEECCCCEEEEEEECEEEEECCCHHHHHHEEEE
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQADAFDPSLFGERAGSVFAGIDSLLILA
EEECCEEEECHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHH
CGTSYYSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAAL
HCCHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHH
KHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGVASTKAFTTQLVALFVLAATL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
GKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCEEEECCCCCCE
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRA
ECCCCEEEEHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHH
RGGELYVFADADTHIVNDEGLHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKP
CCCEEEEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
RNLAKSVTVE
HHHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGAGAPAPGAPRRARSVARVADLD
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
AQVRESHLGGVTGIAHTRWATHGAPVTHNAHPIFSSNALALVHNGIIENFEPLREGLRAK
HHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHC
GYAFVSQTDTEVIAHLIHSLYRGNLFAAVQEAVKQLHGAYAIAVIHQDEPHTVVGARQGS
CEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
PLVVGFGEQENFLASDALALAGSTDRFTFLEEGDVCELTLAGVTIVDRDGARAVREVRVV
CEEEECCCCCCCHHHHHHHCCCCCCCEEEECCCCEEEEEEECEEEEECCCHHHHHHEEEE
AAYGGAVELGPYRHFMQKEIFEQPRAIADTIAQADAFDPSLFGERAGSVFAGIDSLLILA
EEECCEEEECHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHH
CGTSYYSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRALVVVISQSGETADTLAAL
HCCHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHH
KHAQALGHAHTLAICNVATSAMVRQTELQFLTHAGTEIGVASTKAFTTQLVALFVLAATL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
GKLRGHVDAAREADYLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCEEEECCCCCCE
SLEGALKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRA
ECCCCEEEEHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHH
RGGELYVFADADTHIVNDEGLHVIRMPEHYGPLSPILHVVPLQLLAYHTACARGTDVDKP
CCCEEEEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
RNLAKSVTVE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]