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The map label for this gene is livM [H]

Identifier: 83720104

GI number: 83720104

Start: 1700333

End: 1701538

Strand: Reverse

Name: livM [H]

Synonym: BTH_I1502

Alternate gene names: 83720104

Gene position: 1701538-1700333 (Counterclockwise)

Preceding gene: 83719214

Following gene: 83719301

Centisome position: 44.67

GC content: 68.16

Gene sequence:

>1206_bases
ATGACTTCGACAATCCGTTCTTCCCTTGCCGTCGCGCGCGGCGCGTCGCCCGCTTCATCCACGGCATCCGCCGCATCCGC
TTCACCCGCCGCGCCGCGCTTCGCGCTCGGCCTGCCGCCGCGCCCCGCGCTGCTCTCGCGCCGCGCGTGGCTCGCGCTCG
TCGCGCTGTGCATCGCGGTCGGCATCGGCGTGCCGCTCGCCGCGCTCGTCGCGCCCGAGTCGAGCGCGTTTCATCTGTCA
TCCTACGCAATGACGCTCGCGGGCAAGCTGATGTGCTACGCGATCGCCGCGCTCGCGCTCGATCTCGTCTGGGGCTACTG
CGGCATCCTGAGCCTCGGGCATGGCCTGTTCTTCGCGCTCGGCGGCTATGCGATCGGCATGTACCTGATGCGCGCGATCG
GCCGCGACGGCAAGTACGGCAGCGATCTGCCCGACTTCATGGTGTTCCTCGACTGGCACCGGCTGCCGTGGTACTGGAGC
GGCACCGAGCATCTCGCGTATGCGCTCGCGCTCGTCGTGCTCGCACCCGCCGCGCTCGCGTGGGTGTTCGGCTTCTTCAC
GTTCCGCTCGCGCGTGAAGGGCGTGTATCTGTCGATCATCACGCAGGCGACGACGTTCGCCGCGATGCTGCTCTTCTATC
GCAACGAGACGGGCTTCGGCGGCAACAACGGCTTCACCGATTTCAAACGCATCGCCGGCTTCGCGATCACGTCGCCCGGC
ACGCGCTGCGCGCTGTTCCTGATCACGTTCGCGGCGCTCGTCGCATCGTTCGTCGCCGCGCGCGCGATCGTCACGAGCAA
GCTCGGCCGCGTCGTCACCGCGATCCGCGACGGCGAGACGCGCGTGATGTTCCTCGGCTACAGCCCGCTCGCGTACAAGC
TGTTCGTGTGGGTTGTGTCGGCCGTGCTGTGCGGCATCGCGGGCGCGCTGTACGTGCCGCAGGTCGGCATCATCAATCCG
AGCGAGATGTCGCCCGCGAACTCGATCGAGATGGCGATCTGGGTCGCGGTGGGCGGCCGCGGCACGCTGATCGGCCCGAT
CGTCGGCGCGTTCGCCGTCAACGGCGCGAAGAGCGTGTTCACCGCGTACTTCGCCGAATACTGGCTGTTCTTCCTCGGCC
TCATCTTCGTGCTCGTGCCGCTCGTGCTGCCGCGCGGCATCATGGGCCTCGTCGAAGCCGTCACGCGCAAGGCAACGTCA
CGATGA

Upstream 100 bases:

>100_bases
GTGCTCGCGAAGATCGCGGTGCTCGTGATGATCGTGCTGTTCATCCAGAAACGCCCGCAAGGGATGTTCGCCCTGAAGGG
CCGCAGCGCGGAGGCGTGAC

Downstream 100 bases:

>100_bases
ACGAGAACGTTACGATTCCCAAGCTCGCGCTGCCGGACGGCGGCGATCGGCTCGCCGTCAGCGGCACGGCGCAGATGTCG
CACGTCGTCACGCCTGGCGC

Product: branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTSTIRSSLAVARGASPASSTASAASASPAAPRFALGLPPRPALLSRRAWLALVALCIAVGIGVPLAALVAPESSAFHLS
SYAMTLAGKLMCYAIAALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMRAIGRDGKYGSDLPDFMVFLDWHRLPWYWS
GTEHLAYALALVVLAPAALAWVFGFFTFRSRVKGVYLSIITQATTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPG
TRCALFLITFAALVASFVAARAIVTSKLGRVVTAIRDGETRVMFLGYSPLAYKLFVWVVSAVLCGIAGALYVPQVGIINP
SEMSPANSIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSVFTAYFAEYWLFFLGLIFVLVPLVLPRGIMGLVEAVTRKATS
R

Sequences:

>Translated_401_residues
MTSTIRSSLAVARGASPASSTASAASASPAAPRFALGLPPRPALLSRRAWLALVALCIAVGIGVPLAALVAPESSAFHLS
SYAMTLAGKLMCYAIAALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMRAIGRDGKYGSDLPDFMVFLDWHRLPWYWS
GTEHLAYALALVVLAPAALAWVFGFFTFRSRVKGVYLSIITQATTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPG
TRCALFLITFAALVASFVAARAIVTSKLGRVVTAIRDGETRVMFLGYSPLAYKLFVWVVSAVLCGIAGALYVPQVGIINP
SEMSPANSIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSVFTAYFAEYWLFFLGLIFVLVPLVLPRGIMGLVEAVTRKATS
R
>Mature_400_residues
TSTIRSSLAVARGASPASSTASAASASPAAPRFALGLPPRPALLSRRAWLALVALCIAVGIGVPLAALVAPESSAFHLSS
YAMTLAGKLMCYAIAALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMRAIGRDGKYGSDLPDFMVFLDWHRLPWYWSG
TEHLAYALALVVLAPAALAWVFGFFTFRSRVKGVYLSIITQATTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPGT
RCALFLITFAALVASFVAARAIVTSKLGRVVTAIRDGETRVMFLGYSPLAYKLFVWVVSAVLCGIAGALYVPQVGIINPS
EMSPANSIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSVFTAYFAEYWLFFLGLIFVLVPLVLPRGIMGLVEAVTRKATSR

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=334, Percent_Identity=24.8502994011976, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 42579; Mature: 42448

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTIRSSLAVARGASPASSTASAASASPAAPRFALGLPPRPALLSRRAWLALVALCIAV
CCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHH
GIGVPLAALVAPESSAFHLSSYAMTLAGKLMCYAIAALALDLVWGYCGILSLGHGLFFAL
HHCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGYAIGMYLMRAIGRDGKYGSDLPDFMVFLDWHRLPWYWSGTEHLAYALALVVLAPAALA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHH
WVFGFFTFRSRVKGVYLSIITQATTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCEEECCCC
TRCALFLITFAALVASFVAARAIVTSKLGRVVTAIRDGETRVMFLGYSPLAYKLFVWVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHH
AVLCGIAGALYVPQVGIINPSEMSPANSIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSVF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCHHHHH
TAYFAEYWLFFLGLIFVLVPLVLPRGIMGLVEAVTRKATSR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSTIRSSLAVARGASPASSTASAASASPAAPRFALGLPPRPALLSRRAWLALVALCIAV
CCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHH
GIGVPLAALVAPESSAFHLSSYAMTLAGKLMCYAIAALALDLVWGYCGILSLGHGLFFAL
HHCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGYAIGMYLMRAIGRDGKYGSDLPDFMVFLDWHRLPWYWSGTEHLAYALALVVLAPAALA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHH
WVFGFFTFRSRVKGVYLSIITQATTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCEEECCCC
TRCALFLITFAALVASFVAARAIVTSKLGRVVTAIRDGETRVMFLGYSPLAYKLFVWVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHH
AVLCGIAGALYVPQVGIINPSEMSPANSIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSVF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCHHHHH
TAYFAEYWLFFLGLIFVLVPLVLPRGIMGLVEAVTRKATSR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]