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The map label for this gene is livH [H]

Identifier: 83719214

GI number: 83719214

Start: 1701540

End: 1703168

Strand: Reverse

Name: livH [H]

Synonym: BTH_I1503

Alternate gene names: 83719214

Gene position: 1703168-1701540 (Counterclockwise)

Preceding gene: 83720346

Following gene: 83720104

Centisome position: 44.71

GC content: 70.96

Gene sequence:

>1629_bases
ATGCCCACGCCTTTGAGCCGCGCCGCTCGCGCGCTCGCGGCGCTCGCCGTCTGCGCGGCGCTGTCGCTCGGCGCGCCGAG
CGCGGCGCACGCGGTCACGGCCGCCGACGTCGCCGCGCTCGCCGGCGACGACTTCGATGCGAAGAGCGCCGCGATCGACC
ATCTCGCCGCCGAGCGCGACGCCGCCGCCGCCGCGCTGCTGAATGCGCTCGCGAACGGCGACGCGCTCGCGACCGACGCG
GGACGCATCCTCGTCCAGCACGGCGACGCCGCGCGCGACGCGCTGACGAACGCGCCCGCGCAGGCGGGCGACGCGCAGCC
GGTGATGCTCAACAACCTGCTGCGCACGAAGATCGCGAACGCGCTGTCGGGGCTCGATCTCGCGTCGCCCGCTATCGACA
CGCGCCGCCGCGCGATCGATGCGCTGCTCAAGAGCCCGGATGCCGCGCTCAAGCCGATGATCGACGCCGCGCGTGCGAAG
GAAACCGATCCGGTGCTCAAGCGCCGCCTCGACGCGCTATGGGCGATCGCCGCGCTGCGCGACGCCGATCCCGCGAAGCG
CCTCGAAGCGGTGCGGCTCGTGGCCGCGCGCAGCGATCTCGACATGATCGAGCAGTTGCGCCCGCTCGTCGCGAAGCGCT
CCGACGGCAGCGATGCGGAACCCGATGCCCGCGTGCGCGAAGCCGCGCAGCACGGGCTCGACGCGCTCTATGCGATCCAG
CGCCGCGGCGAGATCGCGGGCACGCTGTTCGCGGGGTTGTCGCTCGGCAGCGTGCTGCTGCTCGCCGCGCTCGGCCTCGC
GATCACGTACGGCCTCATCGGCGTCATCAACATGGCGCACGGCGAGTTCCTGATGATCGGCGCGTATGCGACCTACGTCG
TGCAAACGCTCGTGCAGCGCTATCTGCCGGGCGCGTTCGACTGGTATCCGCTCGCCGCGATTCCGGCGTCGTTTCTGGCG
GCGGCCGCGCTCGGCGTCGTGCTCGAGCGCACGGTGCTCAGGCACCTGTACGGCCGCCCGCTCGAGACGCTGCTTGCGAC
GTTCGGCGTGAGCCTGATCCTGATTCAGGCGACGCGAACGATTTTCGGCGCGCAGAACGTGCAAGTCGTCAATCCGTCCT
GGATGAGCGGCGGCGTGACCGTGATGCAGAACCTGATCCTGCCGTACAACCGCCTCGCGATCCTCGCGTTCGCGCTCGCC
GTCGTCGGCGTCGCGTGGGCGGTGTTGACGAAGACGCGCCTCGGCCTGTTCGTGCGCGCGGTCACGCAGAACCGCCGGAT
GGCCGCCTGCGTCGGCGTGAAGACGGCGCGTGTCGATTCGTATGCGTTCGCGTTCGGCGCGGGCATCGCGGGGCTCGGCG
GCTGCGCGCTATCGCAGATCGGCAACGTCGGCCCGGATCTCGGCCAGAGCTACATCATCGATTCGTTCATGGCGGTCGTG
CTGGGCGGCGTGGGCCAGATCGCGGGCACGGTGCTCGGCGGCTTCGGGCTCGGGCTCGTCAGCAAGGCGATCGAGCCGTT
CTGGGGCGCGGTGCTCGCGAAGATCGCGGTGCTCGTGATGATCGTGCTGTTCATCCAGAAACGCCCGCAAGGGATGTTCG
CCCTGAAGGGCCGCAGCGCGGAGGCGTGA

Upstream 100 bases:

>100_bases
CGCTCGCCTGACGTCCGTGCGGACGCCGCGCGAGCGCGCGGCGCCGTCATCGCGCGCGGCCGCGCCGCGCGCCTTCTTCT
CCTTTCACGAGGACATACCG

Downstream 100 bases:

>100_bases
CATGACTTCGACAATCCGTTCTTCCCTTGCCGTCGCGCGCGGCGCGTCGCCCGCTTCATCCACGGCATCCGCCGCATCCG
CTTCACCCGCCGCGCCGCGC

Product: branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MPTPLSRAARALAALAVCAALSLGAPSAAHAVTAADVAALAGDDFDAKSAAIDHLAAERDAAAAALLNALANGDALATDA
GRILVQHGDAARDALTNAPAQAGDAQPVMLNNLLRTKIANALSGLDLASPAIDTRRRAIDALLKSPDAALKPMIDAARAK
ETDPVLKRRLDALWAIAALRDADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRSDGSDAEPDARVREAAQHGLDALYAIQ
RRGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQRYLPGAFDWYPLAAIPASFLA
AAALGVVLERTVLRHLYGRPLETLLATFGVSLILIQATRTIFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALA
VVGVAWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIIDSFMAVV
LGGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA

Sequences:

>Translated_542_residues
MPTPLSRAARALAALAVCAALSLGAPSAAHAVTAADVAALAGDDFDAKSAAIDHLAAERDAAAAALLNALANGDALATDA
GRILVQHGDAARDALTNAPAQAGDAQPVMLNNLLRTKIANALSGLDLASPAIDTRRRAIDALLKSPDAALKPMIDAARAK
ETDPVLKRRLDALWAIAALRDADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRSDGSDAEPDARVREAAQHGLDALYAIQ
RRGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQRYLPGAFDWYPLAAIPASFLA
AAALGVVLERTVLRHLYGRPLETLLATFGVSLILIQATRTIFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALA
VVGVAWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIIDSFMAVV
LGGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA
>Mature_541_residues
PTPLSRAARALAALAVCAALSLGAPSAAHAVTAADVAALAGDDFDAKSAAIDHLAAERDAAAAALLNALANGDALATDAG
RILVQHGDAARDALTNAPAQAGDAQPVMLNNLLRTKIANALSGLDLASPAIDTRRRAIDALLKSPDAALKPMIDAARAKE
TDPVLKRRLDALWAIAALRDADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRSDGSDAEPDARVREAAQHGLDALYAIQR
RGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQRYLPGAFDWYPLAAIPASFLAA
AALGVVLERTVLRHLYGRPLETLLATFGVSLILIQATRTIFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALAV
VGVAWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIIDSFMAVVL
GGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=312, Percent_Identity=28.525641025641, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 56335; Mature: 56204

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPLSRAARALAALAVCAALSLGAPSAAHAVTAADVAALAGDDFDAKSAAIDHLAAERD
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAAAALLNALANGDALATDAGRILVQHGDAARDALTNAPAQAGDAQPVMLNNLLRTKIAN
HHHHHHHHHHHCCCCEECCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ALSGLDLASPAIDTRRRAIDALLKSPDAALKPMIDAARAKETDPVLKRRLDALWAIAALR
HHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRSDGSDAEPDARVREAAQHGLDALYAIQ
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RRGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
YLPGAFDWYPLAAIPASFLAAAALGVVLERTVLRHLYGRPLETLLATFGVSLILIQATRT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALAVVGVAWAVLTKTRLGLFVRA
HHCCCCEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIIDSFMAVV
HHCCCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
EA
CC
>Mature Secondary Structure 
PTPLSRAARALAALAVCAALSLGAPSAAHAVTAADVAALAGDDFDAKSAAIDHLAAERD
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAAAALLNALANGDALATDAGRILVQHGDAARDALTNAPAQAGDAQPVMLNNLLRTKIAN
HHHHHHHHHHHCCCCEECCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ALSGLDLASPAIDTRRRAIDALLKSPDAALKPMIDAARAKETDPVLKRRLDALWAIAALR
HHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRSDGSDAEPDARVREAAQHGLDALYAIQ
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RRGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
YLPGAFDWYPLAAIPASFLAAAALGVVLERTVLRHLYGRPLETLLATFGVSLILIQATRT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALAVVGVAWAVLTKTRLGLFVRA
HHCCCCEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIIDSFMAVV
HHCCCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
EA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]