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The map label for this gene is hemK [H]

Identifier: 83720020

GI number: 83720020

Start: 3369566

End: 3370423

Strand: Direct

Name: hemK [H]

Synonym: BTH_I2931

Alternate gene names: 83720020

Gene position: 3369566-3370423 (Clockwise)

Preceding gene: 83720975

Following gene: 83720718

Centisome position: 88.46

GC content: 74.01

Gene sequence:

>858_bases
ATGAACACGACGAGCCCCGCGCACGCCACCGCCGCCCGCCTGCTGCGCGCGTCGCCGCTCGACGCGGTCGACGCGCGAAT
CCTGCTCGCGCACGCGCTCGGCTGGAGCCGCACGCAGTTGATCACGCGCGCCGACGAGCCGCTCGACGCGGCGGCGATCG
AGCGCTATCTGGCGCTCGAAGCGCGCCGCGCGGCGGGCGAGCCGGTCGCGCAGCTCACCGGCGCGCGCGAGTTCTTCGGC
CTCGATTTCGACGTCACGCCGGACGTGCTGATCCCGCGCCCGGAGACGGAGCTGCTCGTCGAGACGGCGCTCGACGCGAT
CGACGGCATCGCGTCGCCATGCGTGCTCGATCTCGGCGCGGGCAGCGGCGCGATCGCGGTGTCGATCGCGTCCGTGCGGC
CGGACGCGCGCGTGTGGGCGCTCGACCGCTCGGCCGCCGCGCTCGACGTCGCGCGCCGCAATGCGCGCAAGCTGCTCGAT
CCGGCGCGCGCGGGCGGCCCGCTGCGGTTTCTCGAAAGCGACTGGTACGCGGCGCTCGATCCCGGCCTGCGCTTTCACGT
CGTCGTCAGCAACCCACCGTACATCGCGCGGCACGATCCGCATCTCGCCGAAGGCGACCTGCGCTTCGAGCCGCGCGGCG
CGCTCACCGACGAAGACGACGGCCTCGCCGCGATCCGCACGATCGTTGCGGGCGCGCATGCGTTCGTCGCTCCGGGCGGC
GCGCTGTGGATCGAACACGGTTACGATCAGGCGGCCGCGGTGCGCGCGCTGCTCGAAGCGGCGGGCTTCGCCGACGTCGA
ATCGCTTGCGGATCTCGCATCGATCGAGCGCGCGACGGGCGGCCGCCTGCCCGGCTGA

Upstream 100 bases:

>100_bases
CTCGACGAGCTGATCGCCGCGCTCGTCAGCGAGCACCAGGCCGAGCTGCTCGCGTCGCTCGGCGACGCCGAATGACGCCG
CCCGCCCCACGCGCCCCCCG

Downstream 100 bases:

>100_bases
CGGGGCGCTCGCCGCCCGCCGGCCCAGGTGAAATCCAGTATCATTTCTTTTCTCACGCCCAGCCACAGCAAGGTCAGTCA
TGGACACCCAACAACGCATC

Product: hemK protein

Products: NA

Alternate protein names: M.XfaHemK2P [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MNTTSPAHATAARLLRASPLDAVDARILLAHALGWSRTQLITRADEPLDAAAIERYLALEARRAAGEPVAQLTGAREFFG
LDFDVTPDVLIPRPETELLVETALDAIDGIASPCVLDLGAGSGAIAVSIASVRPDARVWALDRSAAALDVARRNARKLLD
PARAGGPLRFLESDWYAALDPGLRFHVVVSNPPYIARHDPHLAEGDLRFEPRGALTDEDDGLAAIRTIVAGAHAFVAPGG
ALWIEHGYDQAAAVRALLEAAGFADVESLADLASIERATGGRLPG

Sequences:

>Translated_285_residues
MNTTSPAHATAARLLRASPLDAVDARILLAHALGWSRTQLITRADEPLDAAAIERYLALEARRAAGEPVAQLTGAREFFG
LDFDVTPDVLIPRPETELLVETALDAIDGIASPCVLDLGAGSGAIAVSIASVRPDARVWALDRSAAALDVARRNARKLLD
PARAGGPLRFLESDWYAALDPGLRFHVVVSNPPYIARHDPHLAEGDLRFEPRGALTDEDDGLAAIRTIVAGAHAFVAPGG
ALWIEHGYDQAAAVRALLEAAGFADVESLADLASIERATGGRLPG
>Mature_285_residues
MNTTSPAHATAARLLRASPLDAVDARILLAHALGWSRTQLITRADEPLDAAAIERYLALEARRAAGEPVAQLTGAREFFG
LDFDVTPDVLIPRPETELLVETALDAIDGIASPCVLDLGAGSGAIAVSIASVRPDARVWALDRSAAALDVARRNARKLLD
PARAGGPLRFLESDWYAALDPGLRFHVVVSNPPYIARHDPHLAEGDLRFEPRGALTDEDDGLAAIRTIVAGAHAFVAPGG
ALWIEHGYDQAAAVRALLEAAGFADVESLADLASIERATGGRLPG

Specific function: Probable protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=259, Percent_Identity=30.5019305019305, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1787463, Length=269, Percent_Identity=44.9814126394052, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI87082085, Length=182, Percent_Identity=34.0659340659341, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24582226, Length=271, Percent_Identity=27.6752767527675, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR019874
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30074; Mature: 30074

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTSPAHATAARLLRASPLDAVDARILLAHALGWSRTQLITRADEPLDAAAIERYLALE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHH
ARRAAGEPVAQLTGAREFFGLDFDVTPDVLIPRPETELLVETALDAIDGIASPCVLDLGA
HHHHCCCCHHHHHCCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECC
GSGAIAVSIASVRPDARVWALDRSAAALDVARRNARKLLDPARAGGPLRFLESDWYAALD
CCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCHHHCCCCEEEECCCCCEEEC
PGLRFHVVVSNPPYIARHDPHLAEGDLRFEPRGALTDEDDGLAAIRTIVAGAHAFVAPGG
CCCEEEEEECCCCEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCHHEECCCC
ALWIEHGYDQAAAVRALLEAAGFADVESLADLASIERATGGRLPG
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNTTSPAHATAARLLRASPLDAVDARILLAHALGWSRTQLITRADEPLDAAAIERYLALE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHH
ARRAAGEPVAQLTGAREFFGLDFDVTPDVLIPRPETELLVETALDAIDGIASPCVLDLGA
HHHHCCCCHHHHHCCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECC
GSGAIAVSIASVRPDARVWALDRSAAALDVARRNARKLLDPARAGGPLRFLESDWYAALD
CCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCHHHCCCCEEEECCCCCEEEC
PGLRFHVVVSNPPYIARHDPHLAEGDLRFEPRGALTDEDDGLAAIRTIVAGAHAFVAPGG
CCCEEEEEECCCCEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCHHEECCCC
ALWIEHGYDQAAAVRALLEAAGFADVESLADLASIERATGGRLPG
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]