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The map label for this gene is dnaA

Identifier: 83719949

GI number: 83719949

Start: 3690347

End: 3691957

Strand: Direct

Name: dnaA

Synonym: BTH_I3239

Alternate gene names: 83719949

Gene position: 3690347-3691957 (Clockwise)

Preceding gene: 83718972

Following gene: 83720585

Centisome position: 96.88

GC content: 66.36

Gene sequence:

>1611_bases
ATGAACGATTTCTGGCAACACTGTTCCGCGCTATTGGAGCGTGAATTGACGCCCCAACAGTACGTGACGTGGATTAAACC
CTTGGCCCCGGTCGCCTTCGATGCCGCTGCGAACACGCTGTCGATCGCCGCACCGAACCGCTTCAAGCTCGACTGGGTCA
AGAGCCAGTTCTCGGGCCGGATCTCCGATCTGGCCCGAGATTTCTGGAATGCGCCGATCGAAGTGCAATTCGTGCTCGAT
CCGAAGGTGGGCCAGCGCAGCGCCGCCGGCGCGGCGCCGCTCGCGCCCCGCGCGCCGCTGCCGGCGGCCAACCCTGCGCC
GGTTACGGCCGGCCCGGCGCCCTCGGGCGCCGCCGATGCGAACGCGCCCGCGCCCGCCGGCATGAACGCCGCCACCGCGG
CCGCCGTCGCCGCCGTCGCCGCCGCGCAGGCCGCCCAGGCGGCCCAGGCGAACGCCGCCGCGCTGAACGCCGACGAGGCC
GCCGACCTCGACCTGCCGAGCCTCACCGCGCACGAGGCGGCGGCCGGCCGCCGCACGTGGCGCCCCGGCGCGGCGAGCGC
GAACAGCGAAGCCGCCGATTCGATGTACGAGCGCTCGAAGCTGAACCCGGTGCTCACGTTCGACAACTTCGTCACCGGCA
AGGCGAACCAGCTCGCGCGCGCGGCGGCGATCCAGGTGGCCGACAACCCGGGCATCTCGTACAACCCGCTGTTCCTGTAC
GGCGGCGTCGGCCTCGGCAAGACCCACCTGATCCACGCGATCGGCAACCAACTGCTGCTCGACAAGCCGGGCGCGCGCAT
CCGCTACATCCACGCGGAGCAGTATGTGTCCGACGTCGTGAAGGCGTACCAGCGCAAGGCGTTCGACGATTTCAAGCGCT
ACTATCATTCGCTCGATCTGCTGCTCATCGACGACATCCAGTTCTTCTCGGGCAAGTCGCGCACACAGGAAGAGTTCTTC
TACGCGTTCGAGGCGCTCGTCGCGAACAAGGCGCAGGTGATCATCACGAGCGACACGTATCCGAAGGAAATCTCCGGCAT
CGACGATCGCCTGATCTCGCGCTTCGATTCGGGCCTCACTGTCGCGATCGAGCCGCCAGAGCTGGAGATGCGCGTCGCGA
TCCTGATGCGCAAGGCGCAGTCGGAAGGCGTGAGCCTGTCGGAGGACGTCGCGTTCTTCGTCGCGAAGCATCTGCGCTCG
AACGTGCGCGAGCTCGAAGGCGCGCTGCGCAAGATCCTCGCGTACTCGAAGTTTCACGGCCGCGAGATCACGATCGAGCT
GACGAAGGAAGCGCTGAAGGATCTGCTCACCGTGCAGAACCGGCAGATCTCGGTCGAGAACATCCAGAAGACGGTGGCCG
ACTTCTACAACATCAAGGTCGCCGACATGTATTCGAAGAAGCGGCCCGCGAACATCGCGCGGCCGCGGCAGATCGCGATG
TATCTCGCGAAGGAGCTCACGCAGAAGAGCCTGCCCGAAATCGGCGAGCTGTTCGGCGGGCGCGACCACACCACCGTGCT
GCACGCGGTGCGCAAGATCGCCGACGAACGCGGCAAGGACGCCCAGCTCAACCATGAGCTGCACGTGCTCGAACAGACGC
TCAAGGGTTGA

Upstream 100 bases:

>100_bases
GTCCGAGGCACGTCCGCACGGCCGCACCGGGCCTTGTTGCGCATCCGCGACAAGGGCGGCCGCGCGCCCTGCGTGCAAAC
GAAACAACGACAGCTCTTCG

Downstream 100 bases:

>100_bases
TGCGCGCGAGCGCTTGAGAAACGCGGAACCGCCCCAATTTAAAAGGGGCGGTTCGGTTTTGAGGCACAATACTGGTTTGA
CCGCCCGGCCGGCGGCGGGC

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRISDLARDFWNAPIEVQFVLD
PKVGQRSAAGAAPLAPRAPLPAANPAPVTAGPAPSGAADANAPAPAGMNAATAAAVAAVAAAQAAQAAQANAAALNADEA
ADLDLPSLTAHEAAAGRRTWRPGAASANSEAADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLY
GGVGLGKTHLIHAIGNQLLLDKPGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFF
YAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEGVSLSEDVAFFVAKHLRS
NVRELEGALRKILAYSKFHGREITIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAM
YLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERGKDAQLNHELHVLEQTLKG

Sequences:

>Translated_536_residues
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRISDLARDFWNAPIEVQFVLD
PKVGQRSAAGAAPLAPRAPLPAANPAPVTAGPAPSGAADANAPAPAGMNAATAAAVAAVAAAQAAQAAQANAAALNADEA
ADLDLPSLTAHEAAAGRRTWRPGAASANSEAADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLY
GGVGLGKTHLIHAIGNQLLLDKPGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFF
YAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEGVSLSEDVAFFVAKHLRS
NVRELEGALRKILAYSKFHGREITIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAM
YLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERGKDAQLNHELHVLEQTLKG
>Mature_536_residues
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRISDLARDFWNAPIEVQFVLD
PKVGQRSAAGAAPLAPRAPLPAANPAPVTAGPAPSGAADANAPAPAGMNAATAAAVAAVAAAQAAQAAQANAAALNADEA
ADLDLPSLTAHEAAAGRRTWRPGAASANSEAADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLY
GGVGLGKTHLIHAIGNQLLLDKPGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFF
YAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEGVSLSEDVAFFVAKHLRS
NVRELEGALRKILAYSKFHGREITIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAM
YLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERGKDAQLNHELHVLEQTLKG

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=532, Percent_Identity=49.0601503759398, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI226510964, Length=233, Percent_Identity=27.0386266094421, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_BURTA (Q2STL6)

Other databases:

- EMBL:   CP000086
- RefSeq:   YP_443733.1
- ProteinModelPortal:   Q2STL6
- STRING:   Q2STL6
- GeneID:   3850091
- GenomeReviews:   CP000086_GR
- KEGG:   bte:BTH_I3239
- TIGR:   BTH_I3239
- eggNOG:   COG0593
- HOGENOM:   HBG695666
- OMA:   WPLCLRR
- ProtClustDB:   PRK00149
- BioCyc:   BTHA271848:BTH_I3239-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 58462; Mature: 58462

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHCCH
ISDLARDFWNAPIEVQFVLDPKVGQRSAAGAAPLAPRAPLPAANPAPVTAGPAPSGAADA
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NAPAPAGMNAATAAAVAAVAAAQAAQAAQANAAALNADEAADLDLPSLTAHEAAAGRRTW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHCCCCCC
RPGAASANSEAADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLY
CCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHEEEECCCCCCCCCEEEE
GGVGLGKTHLIHAIGNQLLLDKPGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDL
CCCCCCHHHHHHHHCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
LLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLT
EEEECHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHHHHCCCCE
VAIEPPELEMRVAILMRKAQSEGVSLSEDVAFFVAKHLRSNVRELEGALRKILAYSKFHG
EEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
REITIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAM
CEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEHHHHCCCCCCCCCCHHHHHH
YLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERGKDAQLNHELHVLEQTLKG
HHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHCCH
ISDLARDFWNAPIEVQFVLDPKVGQRSAAGAAPLAPRAPLPAANPAPVTAGPAPSGAADA
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NAPAPAGMNAATAAAVAAVAAAQAAQAAQANAAALNADEAADLDLPSLTAHEAAAGRRTW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHCCCCCC
RPGAASANSEAADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLY
CCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHEEEECCCCCCCCCEEEE
GGVGLGKTHLIHAIGNQLLLDKPGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDL
CCCCCCHHHHHHHHCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
LLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLT
EEEECHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHHHHCCCCE
VAIEPPELEMRVAILMRKAQSEGVSLSEDVAFFVAKHLRSNVRELEGALRKILAYSKFHG
EEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
REITIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAM
CEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEHHHHCCCCCCCCCCHHHHHH
YLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERGKDAQLNHELHVLEQTLKG
HHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA