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The map label for this gene is gpmA

Identifier: 83719819

GI number: 83719819

Start: 463539

End: 464291

Strand: Reverse

Name: gpmA

Synonym: BTH_I0416

Alternate gene names: 83719819

Gene position: 464291-463539 (Counterclockwise)

Preceding gene: 83719588

Following gene: 83720556

Centisome position: 12.19

GC content: 66.53

Gene sequence:

>753_bases
ATGTACAAGCTCGTTCTCATCCGCCACGGCGAATCGACCTGGAACAAGGAAAACCGCTTCACCGGCTGGGTCGACGTCGA
CCTGACCGAACAAGGCAACAGCGAAGCCCGGCAGGCCGGGCTGCTCCTGAAGGAAGCCGGCTACACGTTCGATATCGCAT
ACACGTCGGTGCTCAAGCGCGCGATCCGCACGCTCTGGCACGTTCAGGACCAGATGGATCTGATGTACGTGCCCGTCGTC
CATTCGTGGCGGCTGAACGAGCGTCATTACGGCGCGCTGTCGGGCCTGAACAAGGCTGAGACGGCCGCGAAGTACGGCGA
CGAGCAGGTGCTCGTCTGGCGCCGCAGCTACGACACGCCGCCGCCCGCGCTCGAGCCGACCGACGAGCGCGCGCCATACG
GCGATCCGCGCTACGCGAAGGTGCCGCGCGAGCAACTCCCGCTCACCGAGTGCCTGAAGGACACGGTCGCGCGCGTGCTG
CCGCTGTGGAACGAATCGATCGCGCCCGCGGTGAAGGCCGGCAAGCAGGTGCTGATCGCCGCGCACGGCAACTCGATCCG
CGCGCTGGTCAAGTATCTCGACGGCATTTCGGACGCGGACATCGTCGGCCTGAACATTCCGAACGGCGTGCCGCTCGTCT
ACGAGCTCGACGCGAACCTCACGCCCATCCGGCACTACTACCTCGGCGACCCGGAAGCGATCGCGAAGGCGCAGGCCGCC
GTCGCGCAGCAGGGCAAGGCGTCCGCGGCGTAA

Upstream 100 bases:

>100_bases
GCAATCCCGCCATTATAAAATAACCGTCTGACGCGATGTCGCCCCAGAGCCGGGTCCGCATCCGTGCTTACCGCTTCCTC
ACCACCGACCGCAAGCATCT

Downstream 100 bases:

>100_bases
TCCGCCCCGCCGCCCCGCGCGCCGCGCGAACCTGTTTCGCGCGGCGCTGTCTGAACCTAGCCGGCGCTCCCCGTTTCGTC
CCGATCCACAAGGCGTCCGG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNSEARQAGLLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVV
HSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPTDERAPYGDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVKAGKQVLIAAHGNSIRALVKYLDGISDADIVGLNIPNGVPLVYELDANLTPIRHYYLGDPEAIAKAQAA
VAQQGKASAA

Sequences:

>Translated_250_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNSEARQAGLLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVV
HSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPTDERAPYGDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVKAGKQVLIAAHGNSIRALVKYLDGISDADIVGLNIPNGVPLVYELDANLTPIRHYYLGDPEAIAKAQAA
VAQQGKASAA
>Mature_250_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNSEARQAGLLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVV
HSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPTDERAPYGDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVKAGKQVLIAAHGNSIRALVKYLDGISDADIVGLNIPNGVPLVYELDANLTPIRHYYLGDPEAIAKAQAA
VAQQGKASAA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=253, Percent_Identity=58.102766798419, Blast_Score=311, Evalue=4e-85,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=61.0441767068273, Blast_Score=302, Evalue=2e-82,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=59.0361445783133, Blast_Score=288, Evalue=4e-78,
Organism=Homo sapiens, GI4502445, Length=257, Percent_Identity=51.7509727626459, Blast_Score=266, Evalue=1e-71,
Organism=Homo sapiens, GI40353764, Length=257, Percent_Identity=51.7509727626459, Blast_Score=266, Evalue=1e-71,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=62.3456790123457, Blast_Score=197, Evalue=9e-51,
Organism=Escherichia coli, GI1786970, Length=245, Percent_Identity=65.7142857142857, Blast_Score=330, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=53.6585365853659, Blast_Score=249, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6324516, Length=291, Percent_Identity=35.0515463917526, Blast_Score=159, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320183, Length=296, Percent_Identity=32.7702702702703, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=53.2, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=53.6, Blast_Score=260, Evalue=5e-70,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=53.6, Blast_Score=260, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=53.6, Blast_Score=260, Evalue=5e-70,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=42.2310756972112, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=42.2310756972112, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=42.2310756972112, Blast_Score=187, Evalue=6e-48,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_BURTA (Q2T1H5)

Other databases:

- EMBL:   CP000086
- RefSeq:   YP_440974.1
- HSSP:   P0A5R6
- ProteinModelPortal:   Q2T1H5
- SMR:   Q2T1H5
- STRING:   Q2T1H5
- GeneID:   3849748
- GenomeReviews:   CP000086_GR
- KEGG:   bte:BTH_I0416
- TIGR:   BTH_I0416
- eggNOG:   COG0588
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK14115
- BioCyc:   BTHA271848:BTH_I0416-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 27834; Mature: 27834

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNSEARQAGLLLKEAGYTFDIAYTSVLKR
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHHHCEEEECCCCEEEHHHHHHHHH
AIRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTP
HHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEPTDERAPYGDPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIA
CCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEE
AHGNSIRALVKYLDGISDADIVGLNIPNGVPLVYELDANLTPIRHYYLGDPEAIAKAQAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHH
VAQQGKASAA
HHHCCCCCCC
>Mature Secondary Structure
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNSEARQAGLLLKEAGYTFDIAYTSVLKR
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHHHCEEEECCCCEEEHHHHHHHHH
AIRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTP
HHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEPTDERAPYGDPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIA
CCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEE
AHGNSIRALVKYLDGISDADIVGLNIPNGVPLVYELDANLTPIRHYYLGDPEAIAKAQAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHH
VAQQGKASAA
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA