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The map label for this gene is garD [H]

Identifier: 83719740

GI number: 83719740

Start: 220786

End: 222480

Strand: Direct

Name: garD [H]

Synonym: BTH_I0190

Alternate gene names: 83719740

Gene position: 220786-222480 (Clockwise)

Preceding gene: 83719461

Following gene: 83720416

Centisome position: 5.8

GC content: 69.79

Gene sequence:

>1695_bases
ATGCGGTCGCGATGCGGTACCTGGTGCCGGACTGGACGTTCGACAACAAGCGCCCCTGTCTCGTGCGCTGAACGAAGCCG
ACTCTTCATGGAGCGCTCGATGCGGGAGCCCACATCGCCCGACGGCACGCGCACGGAGCGCGCGCTGACGATTCGCGTGC
ACGAAAGCGACAACGTCGCGATCGTCGTCAACGCGCGCGGGCTGCCCGCCGGCGCGATACTCGCCGACGGCACCGCGCTC
GTCGAAGGCGTGCCGCAGGGCCACAAGGTCGCGCTCGCCGATCTCGCCGAGGGCGACGCGGTGGTCCGCTACGGCGAGGT
GATCGGCCATGCGGCGAAGCCGCTGCCGCGCGGCGTCTGGGTGGGCGAGCACGCGGTGAAGCTGCCGCTCGCGCCCGCGC
TCGACGAACTGCCGCTCGCGACGCGCGCCGCCGCGAAGCGGCCGAAGCTCGACGGCTACACGTTCGACGGCTATCGGAAC
GCGGACGGCACGGTCGGCACGAAGAACGTGCTCGGCATCATGACGAGCGTGCAGTGCGTCGCCGGCGTGACCGACCACGT
GGTCGCGCGGATCAAGCGCGAGCTGCTGCCGCGCTATCCGAACGTCGACGACGTCGTCGCGCTGAATCACACGTACGGCT
GCGGCGTCGCGATCAACGCGCCGGCCGCGATCGTGCCGATCCGCACGTTGCAGAACCTCGCGCTCAATCCGAATTTCGGC
GGCGAGGTGATGGTGATCGGCCTCGGCTGCGAGAAGCTCGCGCCGGAGCGGCTCGTGCCGGCATCGCTCGCGCCGGGCGG
ACGCATTCCGATCGGGGTCGCGGGCACGGCCGATTCGCCCGTGCTTCGTTTGCAGGACGAAGCGTTCGGCGGCTTCGGCG
CGATGGTCGACGCGATCATGGAGATGGCGGACAAACGCCTCGATCAGTTGAACCGCCGCCGTCGCGAATCGTGTCCGGCG
TCCGACCTCGTCGTCGGCGTGCAATGCGGCGGCAGCGATGCGTTCTCGGGCGTCACCGCGAACCCGGCCGTCGGCTTCGC
GGCCGGCCTGATCGTGCGCGCGGGCGGCACCGTGATGTTCTCCGAAGTGACCGAAGTGCGCGATGCGATTCATCTGCTGA
CGCCGCGCGCGATCGACGCGGAAGTCGGCCGCGCGCTGTTGCGCGAGATGGCGTGGTACGACGATTACCTGTTGCGCGGC
GAGACCGATCGCAGCGCGAATCCGTCGCCGGGCAACAAGACGGGCGGATTGTCGAACGTCGTCGAGAAGGCGCTCGGCTC
GATCGTGAAGTCGGGCACGAGCCCGATCGTCGACGTGCTCGGCCCCGGCCAGAGGATGCGCCGCAAGGGGCTCATCTTCG
CGGCGACGCCCGCTAGCGATTTCGTCTGCGGCACGCTGCAGCTCGCGTCGGGCATCAACCTGCAGGTGTTCACGACGGGG
CGCGGCACGCCGTACGGCCTCGCGATGGCGCCCGTCGTCAAGGTGGCGACGCGCAAGGCGTTGAGCGAGCGCTGGCACGA
CCTGATCGACCTCGATGCGGGGCGCATCGCGACCGGCGAGGCGAGCATCGCCGACGTCGGCTGGGAGCTGTTCCATCTGA
TTCTCGACGTCGCGAGCGGCCGCCGCCAGGTGTGCGCCGACAAGCTCGGGCTGCACAACGCGCTCGTCCTGTTCAATCCC
GCGCCGGTGACCTGA

Upstream 100 bases:

>100_bases
GCGGTGCCGCAGCGTGGCGGGCTCGGCGTCGAGATCGACGAGGACGCGCTCGCCGGCGCACACGAGCTGTATCTGGAGCA
CGGCCTCGGCAGCCGCGACG

Downstream 100 bases:

>100_bases
TCATGACCGACCTCCATCATTCGAACCAGGATGCGAACGCGGCGGGCGGCGATCCGCTCGACGGCGTTCCCACGCACTGC
GGCCGCATTCTGTTGACGGG

Product: D-galactarate dehydratase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MRSRCGTWCRTGRSTTSAPVSCAERSRLFMERSMREPTSPDGTRTERALTIRVHESDNVAIVVNARGLPAGAILADGTAL
VEGVPQGHKVALADLAEGDAVVRYGEVIGHAAKPLPRGVWVGEHAVKLPLAPALDELPLATRAAAKRPKLDGYTFDGYRN
ADGTVGTKNVLGIMTSVQCVAGVTDHVVARIKRELLPRYPNVDDVVALNHTYGCGVAINAPAAIVPIRTLQNLALNPNFG
GEVMVIGLGCEKLAPERLVPASLAPGGRIPIGVAGTADSPVLRLQDEAFGGFGAMVDAIMEMADKRLDQLNRRRRESCPA
SDLVVGVQCGGSDAFSGVTANPAVGFAAGLIVRAGGTVMFSEVTEVRDAIHLLTPRAIDAEVGRALLREMAWYDDYLLRG
ETDRSANPSPGNKTGGLSNVVEKALGSIVKSGTSPIVDVLGPGQRMRRKGLIFAATPASDFVCGTLQLASGINLQVFTTG
RGTPYGLAMAPVVKVATRKALSERWHDLIDLDAGRIATGEASIADVGWELFHLILDVASGRRQVCADKLGLHNALVLFNP
APVT

Sequences:

>Translated_564_residues
MRSRCGTWCRTGRSTTSAPVSCAERSRLFMERSMREPTSPDGTRTERALTIRVHESDNVAIVVNARGLPAGAILADGTAL
VEGVPQGHKVALADLAEGDAVVRYGEVIGHAAKPLPRGVWVGEHAVKLPLAPALDELPLATRAAAKRPKLDGYTFDGYRN
ADGTVGTKNVLGIMTSVQCVAGVTDHVVARIKRELLPRYPNVDDVVALNHTYGCGVAINAPAAIVPIRTLQNLALNPNFG
GEVMVIGLGCEKLAPERLVPASLAPGGRIPIGVAGTADSPVLRLQDEAFGGFGAMVDAIMEMADKRLDQLNRRRRESCPA
SDLVVGVQCGGSDAFSGVTANPAVGFAAGLIVRAGGTVMFSEVTEVRDAIHLLTPRAIDAEVGRALLREMAWYDDYLLRG
ETDRSANPSPGNKTGGLSNVVEKALGSIVKSGTSPIVDVLGPGQRMRRKGLIFAATPASDFVCGTLQLASGINLQVFTTG
RGTPYGLAMAPVVKVATRKALSERWHDLIDLDAGRIATGEASIADVGWELFHLILDVASGRRQVCADKLGLHNALVLFNP
APVT
>Mature_564_residues
MRSRCGTWCRTGRSTTSAPVSCAERSRLFMERSMREPTSPDGTRTERALTIRVHESDNVAIVVNARGLPAGAILADGTAL
VEGVPQGHKVALADLAEGDAVVRYGEVIGHAAKPLPRGVWVGEHAVKLPLAPALDELPLATRAAAKRPKLDGYTFDGYRN
ADGTVGTKNVLGIMTSVQCVAGVTDHVVARIKRELLPRYPNVDDVVALNHTYGCGVAINAPAAIVPIRTLQNLALNPNFG
GEVMVIGLGCEKLAPERLVPASLAPGGRIPIGVAGTADSPVLRLQDEAFGGFGAMVDAIMEMADKRLDQLNRRRRESCPA
SDLVVGVQCGGSDAFSGVTANPAVGFAAGLIVRAGGTVMFSEVTEVRDAIHLLTPRAIDAEVGRALLREMAWYDDYLLRG
ETDRSANPSPGNKTGGLSNVVEKALGSIVKSGTSPIVDVLGPGQRMRRKGLIFAATPASDFVCGTLQLASGINLQVFTTG
RGTPYGLAMAPVVKVATRKALSERWHDLIDLDAGRIATGEASIADVGWELFHLILDVASGRRQVCADKLGLHNALVLFNP
APVT

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=521, Percent_Identity=65.0671785028791, Blast_Score=708, Evalue=0.0,
Organism=Escherichia coli, GI1789475, Length=518, Percent_Identity=32.4324324324324, Blast_Score=232, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 59481; Mature: 59481

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRCGTWCRTGRSTTSAPVSCAERSRLFMERSMREPTSPDGTRTERALTIRVHESDNVA
CCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCEE
IVVNARGLPAGAILADGTALVEGVPQGHKVALADLAEGDAVVRYGEVIGHAAKPLPRGVW
EEEECCCCCCCCEEECCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEE
VGEHAVKLPLAPALDELPLATRAAAKRPKLDGYTFDGYRNADGTVGTKNVLGIMTSVQCV
CCCCEEECCCCCCHHHCCCHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHH
AGVTDHVVARIKRELLPRYPNVDDVVALNHTYGCGVAINAPAAIVPIRTLQNLALNPNFG
HCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEECCCCEEEEHHHHHHCCCCCCCC
GEVMVIGLGCEKLAPERLVPASLAPGGRIPIGVAGTADSPVLRLQDEAFGGFGAMVDAIM
CEEEEEEECHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEHHHCCCHHHHHHHHH
EMADKRLDQLNRRRRESCPASDLVVGVQCGGSDAFSGVTANPAVGFAAGLIVRAGGTVMF
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHEECCCCEEH
SEVTEVRDAIHLLTPRAIDAEVGRALLREMAWYDDYLLRGETDRSANPSPGNKTGGLSNV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHH
VEKALGSIVKSGTSPIVDVLGPGQRMRRKGLIFAATPASDFVCGTLQLASGINLQVFTTG
HHHHHHHHHHCCCCCEEECCCCCHHHHHCCCEEEECCCCCCEEEHHHHCCCCEEEEEECC
RGTPYGLAMAPVVKVATRKALSERWHDLIDLDAGRIATGEASIADVGWELFHLILDVASG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHCC
RRQVCADKLGLHNALVLFNPAPVT
HHHHHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure
MRSRCGTWCRTGRSTTSAPVSCAERSRLFMERSMREPTSPDGTRTERALTIRVHESDNVA
CCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCEE
IVVNARGLPAGAILADGTALVEGVPQGHKVALADLAEGDAVVRYGEVIGHAAKPLPRGVW
EEEECCCCCCCCEEECCHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEE
VGEHAVKLPLAPALDELPLATRAAAKRPKLDGYTFDGYRNADGTVGTKNVLGIMTSVQCV
CCCCEEECCCCCCHHHCCCHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHH
AGVTDHVVARIKRELLPRYPNVDDVVALNHTYGCGVAINAPAAIVPIRTLQNLALNPNFG
HCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEECCCCEEEEHHHHHHCCCCCCCC
GEVMVIGLGCEKLAPERLVPASLAPGGRIPIGVAGTADSPVLRLQDEAFGGFGAMVDAIM
CEEEEEEECHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEHHHCCCHHHHHHHHH
EMADKRLDQLNRRRRESCPASDLVVGVQCGGSDAFSGVTANPAVGFAAGLIVRAGGTVMF
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHEECCCCEEH
SEVTEVRDAIHLLTPRAIDAEVGRALLREMAWYDDYLLRGETDRSANPSPGNKTGGLSNV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHH
VEKALGSIVKSGTSPIVDVLGPGQRMRRKGLIFAATPASDFVCGTLQLASGINLQVFTTG
HHHHHHHHHHCCCCCEEECCCCCHHHHHCCCEEEECCCCCCEEEHHHHCCCCEEEEEECC
RGTPYGLAMAPVVKVATRKALSERWHDLIDLDAGRIATGEASIADVGWELFHLILDVASG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHCC
RRQVCADKLGLHNALVLFNPAPVT
HHHHHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]