Click here to switch to the map view.

The map label for this gene is tctD [H]

Identifier: 83719681

GI number: 83719681

Start: 739928

End: 740803

Strand: Reverse

Name: tctD [H]

Synonym: BTH_I0642

Alternate gene names: 83719681

Gene position: 740803-739928 (Counterclockwise)

Preceding gene: 83719838

Following gene: 83719031

Centisome position: 19.45

GC content: 68.72

Gene sequence:

>876_bases
GTGCGCGAATGCAGACACTGTATAAAAAAACAGTGGTTTATGCAAGCCCGCGTTGCAGGCAGGCATCGCCGCATATTTCG
GAGACAGCCGCGCGCAGCGCCATTGCCGCGGAGCGGCAACCGGTTGCGCATCATGCGAATTCTCATCGCCGAAGACGACA
GCATACTCGCGGACGGCCTCACCCGGTCACTCCGCCAATCGGGCTATGCCGTCGATCACGTGAGGAACGGCGTCGAGGCC
GACACGGCCCTGTCGATGCAGGCTTTCGACCTGCTGATCCTCGATCTCGGCCTGCCCAGAATGCCCGGCCTCGACGTGCT
GCGCCGCCTGCGCGCGCGCAATTCGAACCTGCCCGTGCTGATCCTGACGGCCGCCGACAGCGTCGACGAGCGCGTGAAAG
GGCTCGATCTCGGCGCCGACGACTACATGGCGAAGCCGTTCGCGCTCAACGAGCTCGAGGCGCGCGTGCGCGCGCTGACG
CGGCGCGGCGCGGGCGGCGGGCCGACCGTCGTGCGGCACGGCTCGCTGTCGTTCGACCAGGTCGGCCGGATCGCGTATGC
GAACGACCGCGTGCTCGAGCTGTCCGCGCGCGAGCTCGGCCTGCTCGAAGTGCTGCTGCAGCGGATCGGCCGGCTGGTAT
CGAAGGAGCAGCTCGTCGATCATCTGTGCGAATGGGGCGAGGAAGTCAGCAACAACGCGATCGAGGTCTACGTCCACCGG
CTGCGCAAGAAGATCGAGCCGAGCGGCGTGCGGATCACGACCGTGCGCGGCCTCGGCTACTGCCTCGAGAAGGCGGCGCC
CGCGCCCGCGAGCGACGCGCCGACCGGCGCCGCGCCGCCGCCGGCCGAAGCCGGCGCGAGCCAGTCGCTGCGCTAG

Upstream 100 bases:

>100_bases
CCCGGAGCCTTTCTTGCTTTCTTCCATGAATCGTCCTTTGCTATGATGAGCAGCGTCTGATACGGACGCACCGGCTTCGA
CACGACCAGCAAGCCGTTAG

Downstream 100 bases:

>100_bases
CGCCGCCCACGAGCGAGCGGCCGAAGGCCATGCCGGTCCGTTCCTTCCACGCCGCGCACCGTGCGGCCGCCGCGGCGCCC
GATGCGGACGCCGCGCGCGA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRECRHCIKKQWFMQARVAGRHRRIFRRQPRAAPLPRSGNRLRIMRILIAEDDSILADGLTRSLRQSGYAVDHVRNGVEA
DTALSMQAFDLLILDLGLPRMPGLDVLRRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALT
RRGAGGGPTVVRHGSLSFDQVGRIAYANDRVLELSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHR
LRKKIEPSGVRITTVRGLGYCLEKAAPAPASDAPTGAAPPPAEAGASQSLR

Sequences:

>Translated_291_residues
MRECRHCIKKQWFMQARVAGRHRRIFRRQPRAAPLPRSGNRLRIMRILIAEDDSILADGLTRSLRQSGYAVDHVRNGVEA
DTALSMQAFDLLILDLGLPRMPGLDVLRRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALT
RRGAGGGPTVVRHGSLSFDQVGRIAYANDRVLELSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHR
LRKKIEPSGVRITTVRGLGYCLEKAAPAPASDAPTGAAPPPAEAGASQSLR
>Mature_291_residues
MRECRHCIKKQWFMQARVAGRHRRIFRRQPRAAPLPRSGNRLRIMRILIAEDDSILADGLTRSLRQSGYAVDHVRNGVEA
DTALSMQAFDLLILDLGLPRMPGLDVLRRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALT
RRGAGGGPTVVRHGSLSFDQVGRIAYANDRVLELSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHR
LRKKIEPSGVRITTVRGLGYCLEKAAPAPASDAPTGAAPPPAEAGASQSLR

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=45.4128440366972, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=42.6605504587156, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=39.6396396396396, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.7321428571429, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=36.6515837104072, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=34.841628959276, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=34.9344978165939, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=33.7837837837838, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=31.7596566523605, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=31.6964285714286, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=32.618025751073, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=40.8695652173913, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.7610619469027, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=29.6610169491525, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790299, Length=144, Percent_Identity=31.9444444444444, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=31.5789473684211, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=34.2105263157895, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 32157; Mature: 32157

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRECRHCIKKQWFMQARVAGRHRRIFRRQPRAAPLPRSGNRLRIMRILIAEDDSILADGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHH
TRSLRQSGYAVDHVRNGVEADTALSMQAFDLLILDLGLPRMPGLDVLRRLRARNSNLPVL
HHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEE
ILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLSFDQ
EEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHH
VGRIAYANDRVLELSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHR
HCCEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LRKKIEPSGVRITTVRGLGYCLEKAAPAPASDAPTGAAPPPAEAGASQSLR
HHHHCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRECRHCIKKQWFMQARVAGRHRRIFRRQPRAAPLPRSGNRLRIMRILIAEDDSILADGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHH
TRSLRQSGYAVDHVRNGVEADTALSMQAFDLLILDLGLPRMPGLDVLRRLRARNSNLPVL
HHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEE
ILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLSFDQ
EEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHH
VGRIAYANDRVLELSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHR
HCCEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LRKKIEPSGVRITTVRGLGYCLEKAAPAPASDAPTGAAPPPAEAGASQSLR
HHHHCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]