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The map label for this gene is purE [H]

Identifier: 83719452

GI number: 83719452

Start: 765696

End: 766214

Strand: Direct

Name: purE [H]

Synonym: BTH_I0667

Alternate gene names: 83719452

Gene position: 765696-766214 (Clockwise)

Preceding gene: 83721421

Following gene: 83720003

Centisome position: 20.1

GC content: 69.94

Gene sequence:

>519_bases
ATGAGCGAAGTCCAGACCGCCCACACGCACAGCGCGCCGCTCGTCGGCGTGCTGATGGGTTCCAGCTCCGACTGGGACGT
GATGAAGCATGCCGTCGCGATCCTGCAGGAATTCGACGTGCCGTACGAGGCGAAGGTCGTGTCCGCGCACCGGATGCCCG
ACGAGATGTTCGACTACGCGGAGAAGGCGCGCGAGCGCGGCCTGCGCGCGATCATCGCGGGCGCGGGCGGCGCCGCGCAC
CTGCCCGGCATGCTCGCGGCGAAGACGACCGTGCCCGTGCTCGGCGTGCCCGTCGCGAGCAAGTATCTGAAAGGCGTCGA
TTCGCTGCACTCGATCGTGCAGATGCCGAAAGGCGTGCCCGTGGCGACGTTCGCGATCGGCGAGGCCGGCGCGGCGAACG
CGGCGCTCTTCGCGGTGTCGATCCTGTCCGGCACGTCGGTCGACTATGCGAACCGGCTCGCCGCGTTCCGCGTGCGGCAG
AACGAGGCCGCGCACGCGATGACGCTGCCGCCGCTGTGA

Upstream 100 bases:

>100_bases
TCGCGAAGACGAGCGCGAAGTATCAGGAAGCGCTCGAGCGCATCACGGGCAAGACGCTCGACTGACCATCGTCCGATTCA
CCGAAACGAGGAAGCGCACG

Downstream 100 bases:

>100_bases
GGCCGCCGCGCCGCCGCCTGCAACATCGATCGTCCTGACCGCGGCGGGCGCCGCCGCCCGCCGCCACCGACCCTAGACAT
GACTGCACTCCCCAACCCGA

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFDVPYEAKVVSAHRMPDEMFDYAEKARERGLRAIIAGAGGAAH
LPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFRVRQ
NEAAHAMTLPPL

Sequences:

>Translated_172_residues
MSEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFDVPYEAKVVSAHRMPDEMFDYAEKARERGLRAIIAGAGGAAH
LPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFRVRQ
NEAAHAMTLPPL
>Mature_171_residues
SEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFDVPYEAKVVSAHRMPDEMFDYAEKARERGLRAIIAGAGGAAHL
PGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFRVRQN
EAAHAMTLPPL

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=110, Percent_Identity=62.7272727272727, Blast_Score=145, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324702, Length=150, Percent_Identity=56.6666666666667, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 18031; Mature: 17900

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFDVPYEAKVVSAHRMPDEMFDYA
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHH
EKARERGLRAIIAGAGGAAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVP
HHHHHCCCEEEEECCCCHHHCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCC
VATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFRVRQNEAAHAMTLPPL
EEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCCC
>Mature Secondary Structure 
SEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFDVPYEAKVVSAHRMPDEMFDYA
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHH
EKARERGLRAIIAGAGGAAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVP
HHHHHCCCEEEEECCCCHHHCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCC
VATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFRVRQNEAAHAMTLPPL
EEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]