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The map label for this gene is ybdL [H]

Identifier: 83719334

GI number: 83719334

Start: 3749801

End: 3750955

Strand: Reverse

Name: ybdL [H]

Synonym: BTH_I3295

Alternate gene names: 83719334

Gene position: 3750955-3749801 (Counterclockwise)

Preceding gene: 83718455

Following gene: 83718431

Centisome position: 98.47

GC content: 69.0

Gene sequence:

>1155_bases
ATGCAGAGCGCCGCCGCGCCCCGTTCGAAGCTGCCCGACGTCGGCACGACGATCTTCACCGTCATCGGTCAGCTCGCCGC
CGAGCACCAGGCGTTGAATCTGTCGCAGGGCGCGCCGAGCTTCGCGCCCGATCCGGCGCTCGTCGAGCGCGCCGCTCGCG
CGATGCGCGACGGGCACAACCAGTACGCGCCGATGGCGGGCGTCGCCGCGCTGCGCGACGCGCTCGCCGTCAAGACCGAG
CGCCTGTACGGCGGGCGCTACGATCCGGACTCCGAAGTCACCGTCGTCGCGAGCGCGAGCGAGGGGCTCTACGCGGCGAT
CAGCGCGCTTGTTCATCCGGGCGACGAGGTGATCTACTTCGAGCCGTCGTTCGACAGCTACGCGCCGATCGTCCGGCTGC
AGGGCGCGACGCCCGTCGCGATCAAGCTGTCGCCCGACGGCTTTCGCGTGAACTGGGACGAGGTGGCCGCGAAGATCACG
CCGCGCACGCGGATGCTGATCGTCAACACGCCGCACAACCCGAGCGCGACGATCCTCGGCGACGCCGACATCGCGCACCT
TGCGCGGCTCACCGCGGGCACCGACATCGTGGTGCTGTCCGACGAGGTGTACGAGCACGTCGTGTTCGACGGCGCGCGCC
ACCACAGCATGGCGCGTCATCGCGCGCTCGCCGAGCGCAGCGTGATCGTGTCGTCGTTCGGCAAGTCGTATCACGTGACG
GGCTGGCGCGTCGGCTACTGCCTTGCGCCCGCCGAGCTCACGCGCGAGCTGCGCAAGGTCCATCAGTTCATGACGTTCGC
GGCCGATACGCCGATGCAGCACGCGTTCGCCGAAGCGCTCGCCGAGCCGGCGAGCTATCTCGAGCTCGGCGCGTTCTACG
AGCGCAAGCGCGACCTGCTCGCGAGCGAGCTTGCCGGCTCGCGTTTCGAACTGCAGCGCAGCGAGGGCTCGTTCTTCATG
CTCGCGCGCTTTCGGCACTTTTCCGACGAATCGGATGCCGACTTCGTGCTGCGCGCGATTCGCGACGCGCGCGTCGCGAC
GATTCCGCTATCCGCGTTCTACGCGGACGGCACGAACACCGGCTGCATCCGCTTGAGCTTTTCGAAGGACGACGCGACGC
TGATCGAAGGCGCGCGCCGTCTGCGCAGCCTCTGA

Upstream 100 bases:

>100_bases
ACTTTCGATTGTCTCCGGATATTGGCTCGGGCCAAATCGGCATCGTTGCCCCGCGCGCCGCCGATAGCCGGCGCGCGCGC
CCGCGAGCCAAGGAGGATTC

Downstream 100 bases:

>100_bases
CTTGACGCGCCCGTCGCGCCGATCCGGACAAGACCCGACCTCCAGGAGAATCATCGATGAAACGACTGCAATTCCGGCTC
GCGCTCGCCTGCGCATTGAG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHQALNLSQGAPSFAPDPALVERAARAMRDGHNQYAPMAGVAALRDALAVKTE
RLYGGRYDPDSEVTVVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPDGFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGDADIAHLARLTAGTDIVVLSDEVYEHVVFDGARHHSMARHRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAEALAEPASYLELGAFYERKRDLLASELAGSRFELQRSEGSFFM
LARFRHFSDESDADFVLRAIRDARVATIPLSAFYADGTNTGCIRLSFSKDDATLIEGARRLRSL

Sequences:

>Translated_384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHQALNLSQGAPSFAPDPALVERAARAMRDGHNQYAPMAGVAALRDALAVKTE
RLYGGRYDPDSEVTVVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPDGFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGDADIAHLARLTAGTDIVVLSDEVYEHVVFDGARHHSMARHRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAEALAEPASYLELGAFYERKRDLLASELAGSRFELQRSEGSFFM
LARFRHFSDESDADFVLRAIRDARVATIPLSAFYADGTNTGCIRLSFSKDDATLIEGARRLRSL
>Mature_384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHQALNLSQGAPSFAPDPALVERAARAMRDGHNQYAPMAGVAALRDALAVKTE
RLYGGRYDPDSEVTVVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPDGFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGDADIAHLARLTAGTDIVVLSDEVYEHVVFDGARHHSMARHRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAEALAEPASYLELGAFYERKRDLLASELAGSRFELQRSEGSFFM
LARFRHFSDESDADFVLRAIRDARVATIPLSAFYADGTNTGCIRLSFSKDDATLIEGARRLRSL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=33.4177215189873, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=33.4177215189873, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=30.5128205128205, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=30.5128205128205, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=28.7531806615776, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI4507369, Length=374, Percent_Identity=22.7272727272727, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=52.7704485488127, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1788722, Length=356, Percent_Identity=24.438202247191, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788627, Length=344, Percent_Identity=24.7093023255814, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787710, Length=221, Percent_Identity=26.6968325791855, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=424, Percent_Identity=32.5471698113208, Blast_Score=200, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI71994476, Length=424, Percent_Identity=32.5471698113208, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17567369, Length=409, Percent_Identity=29.3398533007335, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=23.0366492146597, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=28.498727735369, Blast_Score=164, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=31.2820512820513, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=31.2820512820513, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=31.2820512820513, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=31.2820512820513, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI18859735, Length=345, Percent_Identity=24.3478260869565, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 41923; Mature: 41923

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHQALNLSQGAPSFAPDPALVERAARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGVAALRDALAVKTERLYGGRYDPDSEVTVVASASEGLYAAISALVHPGDEVIYF
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIKLSPDGFRVNWDEVAAKITPRTRMLIVNTPHNPSATILG
CCCCCCCCCEEEECCCCEEEEEECCCCCEEEHHHHHHEECCCEEEEEEECCCCCCEEEEE
DADIAHLARLTAGTDIVVLSDEVYEHVVFDGARHHSMARHRALAERSVIVSSFGKSYHVT
CCHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAEALAEPASYLELGAFYERKRDLL
EEEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ASELAGSRFELQRSEGSFFMLARFRHFSDESDADFVLRAIRDARVATIPLSAFYADGTNT
HHHHCCCCEEEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHCCCEEEEEEEEEEECCCCC
GCIRLSFSKDDATLIEGARRLRSL
CEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHQALNLSQGAPSFAPDPALVERAARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGVAALRDALAVKTERLYGGRYDPDSEVTVVASASEGLYAAISALVHPGDEVIYF
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIKLSPDGFRVNWDEVAAKITPRTRMLIVNTPHNPSATILG
CCCCCCCCCEEEECCCCEEEEEECCCCCEEEHHHHHHEECCCEEEEEEECCCCCCEEEEE
DADIAHLARLTAGTDIVVLSDEVYEHVVFDGARHHSMARHRALAERSVIVSSFGKSYHVT
CCHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAEALAEPASYLELGAFYERKRDLL
EEEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ASELAGSRFELQRSEGSFFMLARFRHFSDESDADFVLRAIRDARVATIPLSAFYADGTNT
HHHHCCCCEEEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHCCCEEEEEEEEEEECCCCC
GCIRLSFSKDDATLIEGARRLRSL
CEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]