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The map label for this gene is wzb [C]

Identifier: 83719249

GI number: 83719249

Start: 2119527

End: 2120006

Strand: Direct

Name: wzb [C]

Synonym: BTH_I1873

Alternate gene names: 83719249

Gene position: 2119527-2120006 (Clockwise)

Preceding gene: 83720367

Following gene: 83718552

Centisome position: 55.64

GC content: 67.08

Gene sequence:

>480_bases
ATGAAAAGCGTCGCGATCTGTTTCGTCTGCCTCGGCAACATCTGCCGCTCGCCCACCGCGGAAGGGGTGATGCGTCATCA
GGTGGCGGCAGCGGGGCTTGACGCCGTGATCGAGATCGATTCGGCCGGCACGGGCGACTGGCATGTCGGCGAGGCGCCCG
ACGCACGCGCGCAGCAAGCGGCGCGTGCGCGGGGCTACGATCTGTCGACGTTGCGGGCGCGGCAGATCGGCGACGCCGAT
TTCGAACGCTTCGATCTCGTGCTCGCGATGGATTGCGCCAATCTTGCGGAGTTGCGCAAGCGCTGCCCGCCGCAATATCG
GGGCAAGATCCGGCTCCTGATGGCGTACGCGGGCGACGGATCGGCGGGCGAAATCGCCGATCCGTATTTCGGCGGCGCGC
GTGGTTTCGAACAGGTGCTCGATCAGTGCGAGGACGCGTGCCGCGGCCTCCTCGAAAGCCTGCGCGAAACGGCACGCTGA

Upstream 100 bases:

>100_bases
GCGCTGTGAAGCTGAATCCGGCGCAAGCGGGAATCGGCGCGCCTTTGTATAATGGCGCGTTGCTCGTCCGAGCGATTCGC
CGCGAGTGTCCGGCAGCACA

Downstream 100 bases:

>100_bases
AGCGCCGCATACAACCCCTTTTAGTGGCAGGGATACTTGACTAAATTTGTCAAATATTTATACTTGACCAAAATCGTCAA
GATTGCTGCCCATTCAATAC

Product: low molecular weight protein-tyrosine-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDAVIEIDSAGTGDWHVGEAPDARAQQAARARGYDLSTLRARQIGDAD
FERFDLVLAMDCANLAELRKRCPPQYRGKIRLLMAYAGDGSAGEIADPYFGGARGFEQVLDQCEDACRGLLESLRETAR

Sequences:

>Translated_159_residues
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDAVIEIDSAGTGDWHVGEAPDARAQQAARARGYDLSTLRARQIGDAD
FERFDLVLAMDCANLAELRKRCPPQYRGKIRLLMAYAGDGSAGEIADPYFGGARGFEQVLDQCEDACRGLLESLRETAR
>Mature_159_residues
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDAVIEIDSAGTGDWHVGEAPDARAQQAARARGYDLSTLRARQIGDAD
FERFDLVLAMDCANLAELRKRCPPQYRGKIRLLMAYAGDGSAGEIADPYFGGARGFEQVLDQCEDACRGLLESLRETAR

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=150, Percent_Identity=41.3333333333333, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI4757714, Length=150, Percent_Identity=40, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325330, Length=152, Percent_Identity=32.8947368421053, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78706770, Length=152, Percent_Identity=39.4736842105263, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78706772, Length=152, Percent_Identity=39.4736842105263, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78706766, Length=148, Percent_Identity=37.8378378378378, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI78706768, Length=148, Percent_Identity=37.8378378378378, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI78711846, Length=149, Percent_Identity=40.2684563758389, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI78706764, Length=125, Percent_Identity=37.6, Blast_Score=90, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17182; Mature: 17182

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDAVIEIDSAGTGDWHVGEAPDARAQQA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHH
ARARGYDLSTLRARQIGDADFERFDLVLAMDCANLAELRKRCPPQYRGKIRLLMAYAGDG
HHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
SAGEIADPYFGGARGFEQVLDQCEDACRGLLESLRETAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSVAICFVCLGNICRSPTAEGVMRHQVAAAGLDAVIEIDSAGTGDWHVGEAPDARAQQA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHH
ARARGYDLSTLRARQIGDADFERFDLVLAMDCANLAELRKRCPPQYRGKIRLLMAYAGDG
HHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
SAGEIADPYFGGARGFEQVLDQCEDACRGLLESLRETAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]