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The map label for this gene is iscR [H]

Identifier: 83718552

GI number: 83718552

Start: 2120108

End: 2120647

Strand: Direct

Name: iscR [H]

Synonym: BTH_I1874

Alternate gene names: 83718552

Gene position: 2120108-2120647 (Clockwise)

Preceding gene: 83719249

Following gene: 83721504

Centisome position: 55.66

GC content: 65.74

Gene sequence:

>540_bases
ATGAGACTCACCACCAAAGGCCGTTTCGCCGTCACGGCGATGATCGACTTGGCGCTGCGCCAGGAGCAAGGCCCGGTGAC
GCTTGCAGGCATCAGCCAGCGCCAGCGGATTTCGCTCTCCTACCTCGAGCAATTGTTCGGCAAGCTGCGCCGGCATGAAA
TCGTCGAATCGGTCCGCGGACCGGGCGGCGGCTACAACCTCGCGCGCCGTGCGCAGGACGTGACGGTCGCCGACATCATC
ATCGCGGTCGACGAGCCGCTCGATGCGACCCAATGCGGCGGCAAGGGCACGTGCGAAGGCTCGAAGCAGCCCGACGGCCA
TTGCATGACGCACGAGCTCTGGTCGACGCTGAACCAGAAGATGGTCGAATACCTCGATTCGGTGTCGCTGCAGGATCTCG
TCGATCAGCAGCGCGCCCGCGAAGGCACGCCCGCCGTGCTGCGCGACAAGCGCAAGCCCGAGCCCGTCGCGGCGAGCGTC
GAGCCGGTGCGCTCGATTCCGCTCGGCCCGAATTCGGTCTTCAACATCGCGAGCTCATGA

Upstream 100 bases:

>100_bases
GCGCCGCATACAACCCCTTTTAGTGGCAGGGATACTTGACTAAATTTGTCAAATATTTATACTTGACCAAAATCGTCAAG
ATTGCTGCCCATTCAATACC

Downstream 100 bases:

>100_bases
GCGCCGCGCACTGAACGCGGCCCGCACAACGCGCATAACGAATAGTCCCCGCACTGAACGCATACCCGGAGCGATAGATG
AACAACGAGATCCCCCACCT

Product: iron-sulfur cluster assembly transcription factor IscR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGTCEGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASV
EPVRSIPLGPNSVFNIASS

Sequences:

>Translated_179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGTCEGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASV
EPVRSIPLGPNSVFNIASS
>Mature_179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGTCEGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASV
EPVRSIPLGPNSVFNIASS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=137, Percent_Identity=51.8248175182482, Blast_Score=140, Evalue=5e-35,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 19581; Mature: 19581

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYNLARRAQDVTVADIIIAVDEPLDATQCGGKGTCEGSKQPDGHCMTHELWSTLNQK
CCCCCHHHHHHCCCEEHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASVEPVRSIPLGPNSVFNIASS
HHHHHHCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCC
>Mature Secondary Structure
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYNLARRAQDVTVADIIIAVDEPLDATQCGGKGTCEGSKQPDGHCMTHELWSTLNQK
CCCCCHHHHHHCCCEEHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MVEYLDSVSLQDLVDQQRAREGTPAVLRDKRKPEPVAASVEPVRSIPLGPNSVFNIASS
HHHHHHCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]