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The map label for this gene is hutH [H]

Identifier: 83719164

GI number: 83719164

Start: 2043526

End: 2045070

Strand: Direct

Name: hutH [H]

Synonym: BTH_I1820

Alternate gene names: 83719164

Gene position: 2043526-2045070 (Clockwise)

Preceding gene: 83719188

Following gene: 83720225

Centisome position: 53.65

GC content: 70.49

Gene sequence:

>1545_bases
TTGTATAGACAGGACCCCTTCATGATCACGCTGACCCCAGGCCGCCTGACTCTCCCGCAACTGCGCCGGATCGCCCGCGA
GAACGTGCAGATCGCGCTCGATCCCGCGAGCTTCGCCGCGATCGACCGGGGTGCGCAGGCGGTCGCCGACATCGCCGCGA
AGGGCGAGCCGGCGTACGGCATCAACACGGGCTTCGGACGCCTCGCGAGCACGCACATCCCGCACGATCAACTCGAGCTG
CTGCAGAGGAACCTGGTGCTCTCGCACGCGGTGGGCGTCGGCGAGCCGATGGCGCGCCCCGTCGTGCGCCTGCTGATGGC
GCTCAAGCTGTCGAGCCTCGGCCGCGGCCACTCGGGCATCCGCCGCGTCGTGATGGACGCGCTCGTCAAGCTGTTCAACG
CCGACGTGCTGCCGCTCATCCCGGTCAAGGGCTCGGTCGGCGCGTCGGGCGACCTCTCGCCGCTCGCGCACATGTCGGCG
GTGCTGCTCGGCATCGGCGACGTGTTCATTCGCGGCGAGCGCGCGAGCGCGACGGACGGGCTGCGCGTCGCGGGCCTCGC
GCCGCTCACGCTCGAAGCGAAGGAGGGCCTCGCGCTGCTGAACGGCACGCAGGCGTCCACGGCGCTCGCGCTCGACAACC
TGTTCGCGATCGAAGACCTGTACCGCACGGCGCTCGTGTCGGGCGCGCTGTCGGTCGACGCGGCGGCGGGCTCGGTGAAA
CCGTTCGACGCGCGCATCCACGAACTGCGCGGCCATCGCGGCCAGATCGACGCGGCCGCCGCGTACCGGTCGCTGCTCGA
CGGCTCGGCGATCAACGTGTCGCACCGCGACTGCGGCAAGGTGCAGGACCCGTACAGCCTGCGCTGCCAGCCGCAGGTGA
TGGGCGCATGCCTCGACCAGATCCGTCACGCGGCGGGCGTGCTGCTCGTCGAAGCGAACGCGGTGTCGGACAACCCGCTG
ATCTTCCCGGATACGGGCGAGGTGCTCTCGGGCGGGAACTTCCACGCGGAGCCCGTCGCGTTCGCGGCCGACAATCTCGC
GATCGCCGCAGCCGAAATCGGCGCGCTCGCCGAGCGCCGCATCGCGCTTCTCATCGACGCGACGCTCTCCGGCCTGCCCC
CGTTCCTCGTGAGGGACGGCGGCGTGAACTCGGGCTTCATGATCGCGCACGTGACGGCCGCCGCGCTCGCGTCGGAGAAC
AAGACGCTCGCGCATCCGGCGTCGGTCGATTCGCTGCCGACGTCGGCGAACCAGGAAGACCATGTGTCGATGGCGACGTT
CGCCGCGCGCAAGCTCGCGGACATCGCGGAGAACGTCGCGAACATCCTCGCGATCGAGCTGCTCGCCGCCGCGCAGGGCG
TCGACCTGCGCGCGCCGCACGAAACGAGCCCGGCGCTGCAGCACGCGATGGAGACGATCCGCGCGGACGTCGCGCACTAC
GATCTCGACCATTACTTCGCGCCCGACATCGCGGTGGTCGCGCAGCGCGTGCGCGAGCGCGCGTTCGCGACGCTGAGCCC
GCTGTCGTTCGAATCGGAACAATAA

Upstream 100 bases:

>100_bases
CGCGAGCCGCGCCGGCCTAGGGGAAACTCCTAGCCCCGATTTTTGAAAAACAAGTTGTCTATACAACATCGAGTCACTAC
ACTCGTCTCATTCCGAAAAC

Downstream 100 bases:

>100_bases
GACGATGAGCACGCCCGCCTATCAGGAAATCAAGGATTTCATCCTCGCGCGCATTCACGCCGGCGAATGGGCGGAAGGCG
ATCAGGTGCCGTCCGAGAAC

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MYRQDPFMITLTPGRLTLPQLRRIARENVQIALDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLEL
LQRNLVLSHAVGVGEPMARPVVRLLMALKLSSLGRGHSGIRRVVMDALVKLFNADVLPLIPVKGSVGASGDLSPLAHMSA
VLLGIGDVFIRGERASATDGLRVAGLAPLTLEAKEGLALLNGTQASTALALDNLFAIEDLYRTALVSGALSVDAAAGSVK
PFDARIHELRGHRGQIDAAAAYRSLLDGSAINVSHRDCGKVQDPYSLRCQPQVMGACLDQIRHAAGVLLVEANAVSDNPL
IFPDTGEVLSGGNFHAEPVAFAADNLAIAAAEIGALAERRIALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASEN
KTLAHPASVDSLPTSANQEDHVSMATFAARKLADIAENVANILAIELLAAAQGVDLRAPHETSPALQHAMETIRADVAHY
DLDHYFAPDIAVVAQRVRERAFATLSPLSFESEQ

Sequences:

>Translated_514_residues
MYRQDPFMITLTPGRLTLPQLRRIARENVQIALDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLEL
LQRNLVLSHAVGVGEPMARPVVRLLMALKLSSLGRGHSGIRRVVMDALVKLFNADVLPLIPVKGSVGASGDLSPLAHMSA
VLLGIGDVFIRGERASATDGLRVAGLAPLTLEAKEGLALLNGTQASTALALDNLFAIEDLYRTALVSGALSVDAAAGSVK
PFDARIHELRGHRGQIDAAAAYRSLLDGSAINVSHRDCGKVQDPYSLRCQPQVMGACLDQIRHAAGVLLVEANAVSDNPL
IFPDTGEVLSGGNFHAEPVAFAADNLAIAAAEIGALAERRIALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASEN
KTLAHPASVDSLPTSANQEDHVSMATFAARKLADIAENVANILAIELLAAAQGVDLRAPHETSPALQHAMETIRADVAHY
DLDHYFAPDIAVVAQRVRERAFATLSPLSFESEQ
>Mature_514_residues
MYRQDPFMITLTPGRLTLPQLRRIARENVQIALDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLEL
LQRNLVLSHAVGVGEPMARPVVRLLMALKLSSLGRGHSGIRRVVMDALVKLFNADVLPLIPVKGSVGASGDLSPLAHMSA
VLLGIGDVFIRGERASATDGLRVAGLAPLTLEAKEGLALLNGTQASTALALDNLFAIEDLYRTALVSGALSVDAAAGSVK
PFDARIHELRGHRGQIDAAAAYRSLLDGSAINVSHRDCGKVQDPYSLRCQPQVMGACLDQIRHAAGVLLVEANAVSDNPL
IFPDTGEVLSGGNFHAEPVAFAADNLAIAAAEIGALAERRIALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASEN
KTLAHPASVDSLPTSANQEDHVSMATFAARKLADIAENVANILAIELLAAAQGVDLRAPHETSPALQHAMETIRADVAHY
DLDHYFAPDIAVVAQRVRERAFATLSPLSFESEQ

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=510, Percent_Identity=44.5098039215686, Blast_Score=418, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17567831, Length=506, Percent_Identity=42.8853754940711, Blast_Score=370, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 54124; Mature: 54124

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00488 PAL_HISTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRQDPFMITLTPGRLTLPQLRRIARENVQIALDPASFAAIDRGAQAVADIAAKGEPAYG
CCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCC
INTGFGRLASTHIPHDQLELLQRNLVLSHAVGVGEPMARPVVRLLMALKLSSLGRGHSGI
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
RRVVMDALVKLFNADVLPLIPVKGSVGASGDLSPLAHMSAVLLGIGDVFIRGERASATDG
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHEEECCCCCCCCC
LRVAGLAPLTLEAKEGLALLNGTQASTALALDNLFAIEDLYRTALVSGALSVDAAAGSVK
EEEECCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
PFDARIHELRGHRGQIDAAAAYRSLLDGSAINVSHRDCGKVQDPYSLRCQPQVMGACLDQ
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
IRHAAGVLLVEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLAIAAAEIGALAERR
HHHHHCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHH
IALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQED
EEEEEECHHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
HVSMATFAARKLADIAENVANILAIELLAAAQGVDLRAPHETSPALQHAMETIRADVAHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DLDHYFAPDIAVVAQRVRERAFATLSPLSFESEQ
CCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYRQDPFMITLTPGRLTLPQLRRIARENVQIALDPASFAAIDRGAQAVADIAAKGEPAYG
CCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCC
INTGFGRLASTHIPHDQLELLQRNLVLSHAVGVGEPMARPVVRLLMALKLSSLGRGHSGI
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
RRVVMDALVKLFNADVLPLIPVKGSVGASGDLSPLAHMSAVLLGIGDVFIRGERASATDG
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHEEECCCCCCCCC
LRVAGLAPLTLEAKEGLALLNGTQASTALALDNLFAIEDLYRTALVSGALSVDAAAGSVK
EEEECCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
PFDARIHELRGHRGQIDAAAAYRSLLDGSAINVSHRDCGKVQDPYSLRCQPQVMGACLDQ
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
IRHAAGVLLVEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLAIAAAEIGALAERR
HHHHHCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHH
IALLIDATLSGLPPFLVRDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQED
EEEEEECHHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
HVSMATFAARKLADIAENVANILAIELLAAAQGVDLRAPHETSPALQHAMETIRADVAHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DLDHYFAPDIAVVAQRVRERAFATLSPLSFESEQ
CCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA