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The map label for this gene is panE-3

Identifier: 83718638

GI number: 83718638

Start: 2387845

End: 2388834

Strand: Direct

Name: panE-3

Synonym: BTH_I2115

Alternate gene names: NA

Gene position: 2387845-2388834 (Clockwise)

Preceding gene: 83721522

Following gene: 83720228

Centisome position: 62.69

GC content: 73.54

Gene sequence:

>990_bases
ATGGATCGGGCACCGGTGCGCGCGGCGATCGTCGGAATCGGCGCGATCGGCGGACTATTCGCGGCGGCGCTCGCGCGCGC
GGGATGGGACGTGAGCGCGTTCGCGCGAGGCGCGACGCTCGATGCGCTGCGCGAACGCGGGCTGCGCATCGTCGGCGAGT
CCGGCGATGAAACGTCGCTCGCACTGCGCGCGAGCGACGACGCGCATGCGCTCGGCGAACAGGACTGCGTCGTCGTCGCA
TTGAAGGCGCAGGCGCTGCCGGCGCTCGCCGCGCGCATCGCGCCGCTCGTCGGGCCGCGCACGACCCTCGTCGCCGTGAT
GAACGGCCTGCCGTGGTGGTTTTTCGACGGCTTCGGCGGCCCGCTCGACGGCGCCGTGCTCGACGCCATCGACCCGGGCG
GCGTGACGGCCGCGGCGCTGCCGCCCGCGCGCGCGATCGGCTGCGTGGTTCACTTGTCGTCGGCGACGCGCGAGCCGGGC
GTCGTCGTGCGCGGCCGCGGCAACCGGCTGATCGTCGGCGCGCCGCGTCCCGAGTTGCTCGATCCGGCCGCGCGCGTCGC
CGACGCGCTCGCGGCGGGCGGCTTCGACGTCGAGCGCTCGGCCGACATTCGCACCGACATCTGGGCGAAGCTCTGGGGCA
ACATGAACATGAATCCGCTGAGCGCGCTGACGGGCTCGGCGGCGGACCGCCTGCTCGACGATCCGCTGACGAACGCGCTC
GCGCTGCGGATGATGGAGGAGGCCGACTCGATCGGCGCGCGGCTCGGACTGTCGGCGGGGATGAGCGGCGCCGAGCGGAT
CGCGGTGACGCGCCGGCTGGGCGCGTTCAAGACGTCGATGCTACAGGACCTGGAGGCGGGGCGGCCGCTCGAGGTGGGGC
CGATTCTCGGCGTTTTCCCCGAGCTCGGCCGCAAGCTGGGCGTGCCGACGCCGTATTGCGACGCGGTGCTCGGGTTGTTG
CGCCAGCGGGCGTTCAATTCCGGGCTGTGA

Upstream 100 bases:

>100_bases
GCGGCATCGACGAGTGACGGGCGGCCCGCACGGCCAGATGGTTGTGTGCGCAACTATTTGGCTCTATGCTCATCGCTTCA
TCTAACGAGGAGAAGTGCAT

Downstream 100 bases:

>100_bases
CGCGGCGCGCGGCGGACGGCGGCCGAGGGCGTTCGCTCGACGATGCGGGGAGGGGCGACATGGCGTTCGTCGGCACGAGC
GCGGCGGGCGGGTTCCATCG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MDRAPVRAAIVGIGAIGGLFAAALARAGWDVSAFARGATLDALRERGLRIVGESGDETSLALRASDDAHALGEQDCVVVA
LKAQALPALAARIAPLVGPRTTLVAVMNGLPWWFFDGFGGPLDGAVLDAIDPGGVTAAALPPARAIGCVVHLSSATREPG
VVVRGRGNRLIVGAPRPELLDPAARVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPLTNAL
ALRMMEEADSIGARLGLSAGMSGAERIAVTRRLGAFKTSMLQDLEAGRPLEVGPILGVFPELGRKLGVPTPYCDAVLGLL
RQRAFNSGL

Sequences:

>Translated_329_residues
MDRAPVRAAIVGIGAIGGLFAAALARAGWDVSAFARGATLDALRERGLRIVGESGDETSLALRASDDAHALGEQDCVVVA
LKAQALPALAARIAPLVGPRTTLVAVMNGLPWWFFDGFGGPLDGAVLDAIDPGGVTAAALPPARAIGCVVHLSSATREPG
VVVRGRGNRLIVGAPRPELLDPAARVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPLTNAL
ALRMMEEADSIGARLGLSAGMSGAERIAVTRRLGAFKTSMLQDLEAGRPLEVGPILGVFPELGRKLGVPTPYCDAVLGLL
RQRAFNSGL
>Mature_329_residues
MDRAPVRAAIVGIGAIGGLFAAALARAGWDVSAFARGATLDALRERGLRIVGESGDETSLALRASDDAHALGEQDCVVVA
LKAQALPALAARIAPLVGPRTTLVAVMNGLPWWFFDGFGGPLDGAVLDAIDPGGVTAAALPPARAIGCVVHLSSATREPG
VVVRGRGNRLIVGAPRPELLDPAARVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPLTNAL
ALRMMEEADSIGARLGLSAGMSGAERIAVTRRLGAFKTSMLQDLEAGRPLEVGPILGVFPELGRKLGVPTPYCDAVLGLL
RQRAFNSGL

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34030; Mature: 34030

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAPVRAAIVGIGAIGGLFAAALARAGWDVSAFARGATLDALRERGLRIVGESGDETSL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCEEEECCCCCCEE
ALRASDDAHALGEQDCVVVALKAQALPALAARIAPLVGPRTTLVAVMNGLPWWFFDGFGG
EEEECCCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCC
PLDGAVLDAIDPGGVTAAALPPARAIGCVVHLSSATREPGVVVRGRGNRLIVGAPRPELL
CCCCCEEECCCCCCCEECCCCCHHHHHHHEEECCCCCCCCEEEECCCCEEEEECCCCHHC
DPAARVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPLTNAL
CHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALRMMEEADSIGARLGLSAGMSGAERIAVTRRLGAFKTSMLQDLEAGRPLEVGPILGVFP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHH
ELGRKLGVPTPYCDAVLGLLRQRAFNSGL
HHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRAPVRAAIVGIGAIGGLFAAALARAGWDVSAFARGATLDALRERGLRIVGESGDETSL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCEEEECCCCCCEE
ALRASDDAHALGEQDCVVVALKAQALPALAARIAPLVGPRTTLVAVMNGLPWWFFDGFGG
EEEECCCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCC
PLDGAVLDAIDPGGVTAAALPPARAIGCVVHLSSATREPGVVVRGRGNRLIVGAPRPELL
CCCCCEEECCCCCCCEECCCCCHHHHHHHEEECCCCCCCCEEEECCCCEEEEECCCCHHC
DPAARVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPLTNAL
CHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALRMMEEADSIGARLGLSAGMSGAERIAVTRRLGAFKTSMLQDLEAGRPLEVGPILGVFP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHH
ELGRKLGVPTPYCDAVLGLLRQRAFNSGL
HHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]