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The map label for this gene is yfjR [H]

Identifier: 83718633

GI number: 83718633

Start: 3560652

End: 3561521

Strand: Reverse

Name: yfjR [H]

Synonym: BTH_I3122

Alternate gene names: 83718633

Gene position: 3561521-3560652 (Counterclockwise)

Preceding gene: 83720147

Following gene: 83720617

Centisome position: 93.5

GC content: 71.26

Gene sequence:

>870_bases
ATGGACATCGGATTTATCGGCGTGGGCGAGATGGGCAGCGCGATCGCGGCGAATCTGCTGAAGGCGGGGCATCGCGTTCG
GGCGTGGAACCGCTCGGCCGAACGTGTCGAGCCGCTCGTCGCGCTGGGCGCGCAGCGCGTCGCGACGATCGCCGACGCGT
TCTCGGGCGACGCGGTGTTCTCGATGCTCGCCGACGATGAGGCCGCGCGCGGCGTGTTCGACGCGGCGCTCCTCGAACAC
GCGCCGCGCGGCCTCATTCATGTGAACATGGCGACGATTTCGGTCGCGCTTGCCGAGCAGCTCGCGCACGCGCACGCGCA
GCGCGGCATTCACTACGTCGCGGCGCCCGTGATGGGGCGTCCGCACGTCGCGGCGGCCGCGCGCCTCACGATCATCGCGG
CCGGGCCGGCGGAGGCGATCGACCGGATGCAGCCGGCATTCGACGCGATCGGCCAGAAGACGTGGCGGCTCGGCTCGCTG
CCGCAGCACGCGAACGCGGTGAAGATCGCGGCGAACTTCACGATCGCATCGGCGATCGAGACGATGGGCGAGGCGGGCGC
GCTCCTCGCTGCGCACGGCGTCGCGATGAACGACTATCTCGACGTGATCACCAACAGCGTGTTCCCCGGCCCCGTTTATC
AAGGCTACGGCGCGATGATCGCCGAGTCGCGCTACGAGCCGGCGCTGTTCAAGGCGCGGCTCGGCCTGAAGGACGTGCGG
CTCGCGCTCGAGGCGGGCGACGCGGTGTCGGTGCCGCTGCCTGTCGCGAGCGTCGTGCGCGACAGCCTGATCGAAGCGGT
CGCGCACGGCCACGGCGACAAGGACTTCGCGGTGCTCGGCCAGGTCGCGGCGCGCCGCGCGGGGCGGTGA

Upstream 100 bases:

>100_bases
TTGCCGCACATCGCGCGACGCCCGCCGCGAAACGGCAAATGTCGCGCGCCTGTGCTTTACTCGTGCTTTCGACGGACAAG
ACGAATTCAAGGAGCGCGAG

Downstream 100 bases:

>100_bases
CGCACGTGGCGCGGCGTGCGGCGCGCGGCTGTCCCGCTGCAGACAGCCGCGCGCGTTCCCCGGCATAATCGGCGTTTCCA
TTTCAATTTCGAAAGCGGGG

Product: 2-hydroxy-3-oxopropionate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDIGFIGVGEMGSAIAANLLKAGHRVRAWNRSAERVEPLVALGAQRVATIADAFSGDAVFSMLADDEAARGVFDAALLEH
APRGLIHVNMATISVALAEQLAHAHAQRGIHYVAAPVMGRPHVAAAARLTIIAAGPAEAIDRMQPAFDAIGQKTWRLGSL
PQHANAVKIAANFTIASAIETMGEAGALLAAHGVAMNDYLDVITNSVFPGPVYQGYGAMIAESRYEPALFKARLGLKDVR
LALEAGDAVSVPLPVASVVRDSLIEAVAHGHGDKDFAVLGQVAARRAGR

Sequences:

>Translated_289_residues
MDIGFIGVGEMGSAIAANLLKAGHRVRAWNRSAERVEPLVALGAQRVATIADAFSGDAVFSMLADDEAARGVFDAALLEH
APRGLIHVNMATISVALAEQLAHAHAQRGIHYVAAPVMGRPHVAAAARLTIIAAGPAEAIDRMQPAFDAIGQKTWRLGSL
PQHANAVKIAANFTIASAIETMGEAGALLAAHGVAMNDYLDVITNSVFPGPVYQGYGAMIAESRYEPALFKARLGLKDVR
LALEAGDAVSVPLPVASVVRDSLIEAVAHGHGDKDFAVLGQVAARRAGR
>Mature_289_residues
MDIGFIGVGEMGSAIAANLLKAGHRVRAWNRSAERVEPLVALGAQRVATIADAFSGDAVFSMLADDEAARGVFDAALLEH
APRGLIHVNMATISVALAEQLAHAHAQRGIHYVAAPVMGRPHVAAAARLTIIAAGPAEAIDRMQPAFDAIGQKTWRLGSL
PQHANAVKIAANFTIASAIETMGEAGALLAAHGVAMNDYLDVITNSVFPGPVYQGYGAMIAESRYEPALFKARLGLKDVR
LALEAGDAVSVPLPVASVVRDSLIEAVAHGHGDKDFAVLGQVAARRAGR

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40556376, Length=280, Percent_Identity=29.6428571428571, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI23308751, Length=289, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790315, Length=286, Percent_Identity=28.6713286713287, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI145693186, Length=282, Percent_Identity=26.241134751773, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786719, Length=284, Percent_Identity=25.3521126760563, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789092, Length=277, Percent_Identity=25.9927797833935, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574115, Length=279, Percent_Identity=25.089605734767, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655230, Length=285, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19922568, Length=285, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015815
- InterPro:   IPR008927
- InterPro:   IPR006115
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03446 NAD_binding_2 [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 30140; Mature: 30140

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIGFIGVGEMGSAIAANLLKAGHRVRAWNRSAERVEPLVALGAQRVATIADAFSGDAVF
CCCEEEECCCHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SMLADDEAARGVFDAALLEHAPRGLIHVNMATISVALAEQLAHAHAQRGIHYVAAPVMGR
HHHHCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
PHVAAAARLTIIAAGPAEAIDRMQPAFDAIGQKTWRLGSLPQHANAVKIAANFTIASAIE
CCHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHH
TMGEAGALLAAHGVAMNDYLDVITNSVFPGPVYQGYGAMIAESRYEPALFKARLGLKDVR
HHHHCCHHHHHCCCHHHHHHHHHHCCCCCCCHHHCCHHHHHCCCCCHHHHHHHCCHHHHH
LALEAGDAVSVPLPVASVVRDSLIEAVAHGHGDKDFAVLGQVAARRAGR
HHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIGFIGVGEMGSAIAANLLKAGHRVRAWNRSAERVEPLVALGAQRVATIADAFSGDAVF
CCCEEEECCCHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SMLADDEAARGVFDAALLEHAPRGLIHVNMATISVALAEQLAHAHAQRGIHYVAAPVMGR
HHHHCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
PHVAAAARLTIIAAGPAEAIDRMQPAFDAIGQKTWRLGSLPQHANAVKIAANFTIASAIE
CCHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHH
TMGEAGALLAAHGVAMNDYLDVITNSVFPGPVYQGYGAMIAESRYEPALFKARLGLKDVR
HHHHCCHHHHHCCCHHHHHHHHHHCCCCCCCHHHCCHHHHHCCCCCHHHHHHHCCHHHHH
LALEAGDAVSVPLPVASVVRDSLIEAVAHGHGDKDFAVLGQVAARRAGR
HHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]