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The map label for this gene is hoxN [H]

Identifier: 83718602

GI number: 83718602

Start: 2742420

End: 2743814

Strand: Reverse

Name: hoxN [H]

Synonym: BTH_I2409

Alternate gene names: 83718602

Gene position: 2743814-2742420 (Counterclockwise)

Preceding gene: 83721312

Following gene: 83720759

Centisome position: 72.03

GC content: 67.24

Gene sequence:

>1395_bases
ATGCGCCGCACGGCGGCGAGCGGCTCCGGGGTTCAGCGCCGCGGGGAGGCGGCGTGTCGTCCACGGCTGCATCGCGCCGC
TTGTCGCGGCTCGCCCGTTTCATCCCCGTCCGTCGCCGCGCGCTTCGGCGCGCGCCGCGCATGTCGCAGGCATCTGCAGA
TGCGCGCATCGCGGACGCGCACGTCGCGGACGCGCATGTCGCGAACGCGCATGTCGCGAACGCATGCCGGCGCGCGGACG
GCCGATGGACGAAGCGGGGGGCACGCGCATCGCGCGCGATGCCGCGCGTGTTGGCATTCACCTTGTTTGTCGACCGTTCG
CAAAGGGAGCGTCATGCTCAAATCGTTTCTCCGTCTCTTCAACGACAGCCCCGTCGAGCTGCGCAGCAAGATCGTCGGGA
TCTACGCGATGCTGATCGCATTCAACGTCGGCGCGTGGATCTGGGCGTTCGCCGCGTTTCACGGCCAGCCGGTGCTGCTC
GGCACCGCGCTCCTCGCGTATACGTTCGGGCTGCGCCACGCGGTCGACGCCGATCACATCGCCGCGATCGACAACGTCAC
GCGCAAGCTGATGCACGAGAAGAAAAACCCGCTCGGCGCGGGGCTCTTCTTCTCGCTCGGCCATTCGAGCGTCGTGATCC
TGATGACGGTCGCCGTCGCGCTGACGGCCGCGACGCTCGCCGAGCGTTTCGAAGGGATGAAGGCGTGGGGCGGCGTGATC
GGCACGAGCGTGTCGGCGTTCTTCCTGCTCGTGCTCGCGTTCGCGAACCTGCTGATCCTGATCTCGGTGTACCGGACGTT
TCGCGCGGTGCGGCGCGGCGAGCCGCTCGTCGAGCAGGATCTCGACATCCTGCTCAACCGGCGCGGCTTCTTCGCACGGA
TCTTCCGGCCGCTGTTCGCGATCGTGTCGCGCAGCTGGCACCTGTATCCGATCGGCTTCCTGTTCGGCCTCGGCTTCGAC
ACCGCGACCGAGATCGCGCTGTTCGGCATCTCGGCGACGCAGGCGCACGGCGGGCTGTCGTTCTGGTCGGTGATGGCGCT
GCCCGTGCTGTTCACCGCGGGCATGACGCTCGTCGACACCACCGACGGCATCATGATGATGGGCGCGTACCGCTGGGCGT
TCGTGCGGCCGATCCGCAAGATCTACTACAACATGACGATCACGTTCGTGTCGGTGCTCGTCGCCGTGGTGATCGGCGGC
ATCGAGGCGCTCGCCCTCATCGGCGGCAAGCTCTCGCTCAAGGGCGGCCTGTGGGATTTCGCCGCGATGGCGGCCGAGCA
CTTCGGCATGCTCGGCTACTTCGTGATCGGCCTCTTTGCCGCGAGCTGGATCGTCTCGGCGCTCATCTACCGGATCAGGC
GCTACGACGATATCGAGGTGACGATCTCCGTGTGA

Upstream 100 bases:

>100_bases
GCGGCCAACCACTGGACGCATCGCGTCCGGGAAGGTGAAGCGGCGTTTTCGTCAGCCCGGATACCGGCCGAGACACGGGG
GTCGTTCGCCGGTCGCGCGC

Downstream 100 bases:

>100_bases
CGTTTCCCCGTCAAGTTCCGCATGACCCGCGCGCGTTCGCGCACCGCCCTTACACTGACCCGATACCGACCAACGGAACC
ACCATGCAGATGCGCAAAAT

Product: high affinity nickel transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MRRTAASGSGVQRRGEAACRPRLHRAACRGSPVSSPSVAARFGARRACRRHLQMRASRTRTSRTRMSRTRMSRTHAGART
ADGRSGGHAHRARCRACWHSPCLSTVRKGSVMLKSFLRLFNDSPVELRSKIVGIYAMLIAFNVGAWIWAFAAFHGQPVLL
GTALLAYTFGLRHAVDADHIAAIDNVTRKLMHEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGVI
GTSVSAFFLLVLAFANLLILISVYRTFRAVRRGEPLVEQDLDILLNRRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFD
TATEIALFGISATQAHGGLSFWSVMALPVLFTAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAVVIGG
IEALALIGGKLSLKGGLWDFAAMAAEHFGMLGYFVIGLFAASWIVSALIYRIRRYDDIEVTISV

Sequences:

>Translated_464_residues
MRRTAASGSGVQRRGEAACRPRLHRAACRGSPVSSPSVAARFGARRACRRHLQMRASRTRTSRTRMSRTRMSRTHAGART
ADGRSGGHAHRARCRACWHSPCLSTVRKGSVMLKSFLRLFNDSPVELRSKIVGIYAMLIAFNVGAWIWAFAAFHGQPVLL
GTALLAYTFGLRHAVDADHIAAIDNVTRKLMHEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGVI
GTSVSAFFLLVLAFANLLILISVYRTFRAVRRGEPLVEQDLDILLNRRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFD
TATEIALFGISATQAHGGLSFWSVMALPVLFTAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAVVIGG
IEALALIGGKLSLKGGLWDFAAMAAEHFGMLGYFVIGLFAASWIVSALIYRIRRYDDIEVTISV
>Mature_464_residues
MRRTAASGSGVQRRGEAACRPRLHRAACRGSPVSSPSVAARFGARRACRRHLQMRASRTRTSRTRMSRTRMSRTHAGART
ADGRSGGHAHRARCRACWHSPCLSTVRKGSVMLKSFLRLFNDSPVELRSKIVGIYAMLIAFNVGAWIWAFAAFHGQPVLL
GTALLAYTFGLRHAVDADHIAAIDNVTRKLMHEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGVI
GTSVSAFFLLVLAFANLLILISVYRTFRAVRRGEPLVEQDLDILLNRRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFD
TATEIALFGISATQAHGGLSFWSVMALPVLFTAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAVVIGG
IEALALIGGKLSLKGGLWDFAAMAAEHFGMLGYFVIGLFAASWIVSALIYRIRRYDDIEVTISV

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 51001; Mature: 51001

Theoretical pI: Translated: 11.76; Mature: 11.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTAASGSGVQRRGEAACRPRLHRAACRGSPVSSPSVAARFGARRACRRHLQMRASRTR
CCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSRTRMSRTRMSRTHAGARTADGRSGGHAHRARCRACWHSPCLSTVRKGSVMLKSFLRLF
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDSPVELRSKIVGIYAMLIAFNVGAWIWAFAAFHGQPVLLGTALLAYTFGLRHAVDADHI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHH
AAIDNVTRKLMHEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGVI
HHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTSVSAFFLLVLAFANLLILISVYRTFRAVRRGEPLVEQDLDILLNRRGFFARIFRPLFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
IVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLFTAGMTLVDT
HHHCCCCEEEHHHHHHCCCCHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHCCCCEEEC
TDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAVVIGGIEALALIGGKLSLKGGLWDF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHH
AAMAAEHFGMLGYFVIGLFAASWIVSALIYRIRRYDDIEVTISV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure
MRRTAASGSGVQRRGEAACRPRLHRAACRGSPVSSPSVAARFGARRACRRHLQMRASRTR
CCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSRTRMSRTRMSRTHAGARTADGRSGGHAHRARCRACWHSPCLSTVRKGSVMLKSFLRLF
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDSPVELRSKIVGIYAMLIAFNVGAWIWAFAAFHGQPVLLGTALLAYTFGLRHAVDADHI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHH
AAIDNVTRKLMHEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGVI
HHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTSVSAFFLLVLAFANLLILISVYRTFRAVRRGEPLVEQDLDILLNRRGFFARIFRPLFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
IVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLFTAGMTLVDT
HHHCCCCEEEHHHHHHCCCCHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHCCCCEEEC
TDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAVVIGGIEALALIGGKLSLKGGLWDF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHH
AAMAAEHFGMLGYFVIGLFAASWIVSALIYRIRRYDDIEVTISV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]