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The map label for this gene is aroB

Identifier: 83595070

GI number: 83595070

Start: 4291370

End: 4292527

Strand: Direct

Name: aroB

Synonym: Rru_A3741

Alternate gene names: 83595070

Gene position: 4291370-4292527 (Clockwise)

Preceding gene: 83595069

Following gene: 83595071

Centisome position: 98.59

GC content: 69.08

Gene sequence:

>1158_bases
GTGAGCCCAGACACAGCCGCCGATGCCGCCGCCGACCCCGCCTTGCAGTCGTCCGTTCTGACCGTTTCCCTGGGCGAGCG
CAGCTATCCCATTCATATCGGCCCGGGCTTGCTGGGCCGCGCCGGGGCTTTGATCGCCCCCCTCTTGCGCAAGCCCCGGG
TTTTCGTCGTCACCGATGCCACCGTCGCCGCGCTGCATCTCGATCCCTTGCTGGCCTCCCTCGGCGCGGCGGGCATTGCC
CATGATCACGTCGTGCTGCCGGCCGGCGAGGCGACCAAAAGCTTTTCCCAGCTTGAAGAGCTGCTTGATCTTTTGCTGGC
GGCGCGGTTCGAGCGCTCGACCACCCTGCTCGCCCTCGGCGGCGGGGTGATCGGCGATCTGGTCGGCTTCGCCGCCGCCA
TCTTGCTGCGCGGCGTCGATTTCATCCAGATCCCCACCACCTTGCTCGCCCAGGTCGACAGCAGCGTTGGCGGCAAGACC
GGCATCAATACGGCCTATGGCAAGAATCTGGTCGGCGCCTTCCACCAGCCGCGTCTGGTGCTGGCCGACACCACCGTGCT
GGATACCCTGCCCCGCCGCGAATTGCTGGCGGGCTATGGCGAGGTGGTCAAATACGGCGTCATCGATGATCCCGCCTTCT
TCGACTGGCTTGAAGAGCATGGCTCCGCCCTGATCGCCGGTGACGGCGGGGCGCGCATCCACGCCGTTCTGACCGCCTGC
CGCGCCAAGGCCCGGGTGGTCGCCGAGGACGAACGCGAAGGCGGACGCCGCGCCCTGCTCAACCTTGGCCACACCTTCGG
CCACGCGCTGGAGGCCGAAACCGGCTTTGGTCCCACCTTGCTCCATGGCGAGGCGGTGGCCCTCGGCATGGTGATGGCCC
TTGATCTGTCGGTGCGCCTGGGGCTGTGTCCGCCCGCCGACGCCGCCCGCTTGCGCGCCCATCTTGATCACGTCGGCCTG
CCCACCGATCCCCGGCGTCTCGAGGGTGCCCCGGCCTGGAACGCCGAGCGCCTGCTGGCGGCGATGGATCACGACAAGAA
GGTCGAGGATGGCAAGGTGACCTTCGTGCTGGCGCGCGGCATCGGCCGGTCGCTGCTGTGGCGCGAGGCCGATACGGCCA
GCGTGCTCGCCACCCTGCGCGCCGCCGTGGCGCCCTGA

Upstream 100 bases:

>100_bases
ATATCGTTTTCGATGCCCTTGACGAAAGCCAGGACGCCTCCGCCCTGCGGGTGCGCTCGTGCCTTCTTTCCTACCTCGCC
GACCATGCGGAGACCGCCCC

Downstream 100 bases:

>100_bases
GGGCGGGGCCGGGCAAAGGGCGATGGTGGTCATCGGCAAGGGCATCGGTCGGGTTCTAAGGGCTTGGCGCGGCGGCCGGC
GCCACAAACCGGGCAAGGGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSPDTAADAAADPALQSSVLTVSLGERSYPIHIGPGLLGRAGALIAPLLRKPRVFVVTDATVAALHLDPLLASLGAAGIA
HDHVVLPAGEATKSFSQLEELLDLLLAARFERSTTLLALGGGVIGDLVGFAAAILLRGVDFIQIPTTLLAQVDSSVGGKT
GINTAYGKNLVGAFHQPRLVLADTTVLDTLPRRELLAGYGEVVKYGVIDDPAFFDWLEEHGSALIAGDGGARIHAVLTAC
RAKARVVAEDEREGGRRALLNLGHTFGHALEAETGFGPTLLHGEAVALGMVMALDLSVRLGLCPPADAARLRAHLDHVGL
PTDPRRLEGAPAWNAERLLAAMDHDKKVEDGKVTFVLARGIGRSLLWREADTASVLATLRAAVAP

Sequences:

>Translated_385_residues
MSPDTAADAAADPALQSSVLTVSLGERSYPIHIGPGLLGRAGALIAPLLRKPRVFVVTDATVAALHLDPLLASLGAAGIA
HDHVVLPAGEATKSFSQLEELLDLLLAARFERSTTLLALGGGVIGDLVGFAAAILLRGVDFIQIPTTLLAQVDSSVGGKT
GINTAYGKNLVGAFHQPRLVLADTTVLDTLPRRELLAGYGEVVKYGVIDDPAFFDWLEEHGSALIAGDGGARIHAVLTAC
RAKARVVAEDEREGGRRALLNLGHTFGHALEAETGFGPTLLHGEAVALGMVMALDLSVRLGLCPPADAARLRAHLDHVGL
PTDPRRLEGAPAWNAERLLAAMDHDKKVEDGKVTFVLARGIGRSLLWREADTASVLATLRAAVAP
>Mature_384_residues
SPDTAADAAADPALQSSVLTVSLGERSYPIHIGPGLLGRAGALIAPLLRKPRVFVVTDATVAALHLDPLLASLGAAGIAH
DHVVLPAGEATKSFSQLEELLDLLLAARFERSTTLLALGGGVIGDLVGFAAAILLRGVDFIQIPTTLLAQVDSSVGGKTG
INTAYGKNLVGAFHQPRLVLADTTVLDTLPRRELLAGYGEVVKYGVIDDPAFFDWLEEHGSALIAGDGGARIHAVLTACR
AKARVVAEDEREGGRRALLNLGHTFGHALEAETGFGPTLLHGEAVALGMVMALDLSVRLGLCPPADAARLRAHLDHVGLP
TDPRRLEGAPAWNAERLLAAMDHDKKVEDGKVTFVLARGIGRSLLWREADTASVLATLRAAVAP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=346, Percent_Identity=51.4450867052023, Blast_Score=296, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6320332, Length=324, Percent_Identity=39.8148148148148, Blast_Score=198, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_RHORT (Q2RMW0)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428822.1
- ProteinModelPortal:   Q2RMW0
- SMR:   Q2RMW0
- STRING:   Q2RMW0
- GeneID:   3837198
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3741
- NMPDR:   fig|1085.1.peg.1173
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   PRREWIN
- PhylomeDB:   Q2RMW0
- ProtClustDB:   PRK00002
- BioCyc:   RRUB269796:RRU_A3741-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40261; Mature: 40130

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDTAADAAADPALQSSVLTVSLGERSYPIHIGPGLLGRAGALIAPLLRKPRVFVVTDA
CCCCCCCHHHCCCHHHCCEEEEEECCCCCCEEECCCCHHHHHHHHHHHHCCCEEEEEECC
TVAALHLDPLLASLGAAGIAHDHVVLPAGEATKSFSQLEELLDLLLAARFERSTTLLALG
EEEHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GGVIGDLVGFAAAILLRGVDFIQIPTTLLAQVDSSVGGKTGINTAYGKNLVGAFHQPRLV
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHCCCCCEE
LADTTVLDTLPRRELLAGYGEVVKYGVIDDPAFFDWLEEHGSALIAGDGGARIHAVLTAC
EECCHHHHHCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHH
RAKARVVAEDEREGGRRALLNLGHTFGHALEAETGFGPTLLHGEAVALGMVMALDLSVRL
HHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHEEE
GLCPPADAARLRAHLDHVGLPTDPRRLEGAPAWNAERLLAAMDHDKKVEDGKVTFVLARG
CCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECC
IGRSLLWREADTASVLATLRAAVAP
CCHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPDTAADAAADPALQSSVLTVSLGERSYPIHIGPGLLGRAGALIAPLLRKPRVFVVTDA
CCCCCCHHHCCCHHHCCEEEEEECCCCCCEEECCCCHHHHHHHHHHHHCCCEEEEEECC
TVAALHLDPLLASLGAAGIAHDHVVLPAGEATKSFSQLEELLDLLLAARFERSTTLLALG
EEEHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GGVIGDLVGFAAAILLRGVDFIQIPTTLLAQVDSSVGGKTGINTAYGKNLVGAFHQPRLV
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHCCCCCEE
LADTTVLDTLPRRELLAGYGEVVKYGVIDDPAFFDWLEEHGSALIAGDGGARIHAVLTAC
EECCHHHHHCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHH
RAKARVVAEDEREGGRRALLNLGHTFGHALEAETGFGPTLLHGEAVALGMVMALDLSVRL
HHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHEEE
GLCPPADAARLRAHLDHVGLPTDPRRLEGAPAWNAERLLAAMDHDKKVEDGKVTFVLARG
CCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECC
IGRSLLWREADTASVLATLRAAVAP
CCHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA