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The map label for this gene is aroK

Identifier: 83595069

GI number: 83595069

Start: 4290807

End: 4291373

Strand: Direct

Name: aroK

Synonym: Rru_A3740

Alternate gene names: 83595069

Gene position: 4290807-4291373 (Clockwise)

Preceding gene: 83595066

Following gene: 83595070

Centisome position: 98.58

GC content: 66.31

Gene sequence:

>567_bases
ATGATTGAAGCCGAGGAAAACACCCTGGCACTGCCGCGCACCCTGGTTCTGGTCGGGCTGATGGGGGCGGGCAAAACCTG
TATCGGCCGCCGTCTGGCCCAGATGGCCGGGGTGCCGTTCGTCGATGCCGATGTCGAGATCGAGCGCGCCGCCAAACGCA
CCATCGCCGAGATCTTCGCCACCTATGGCGAAAGCGAATTCCGCGCCCTGGAGCGGCGGGTGATGGCCCGGTTGCTGGCG
GGGCGCACCTGCGTGCTGGCCACCGGCGGCGGCGCCTTCATGGCCGAAGACACCCGCGCCCTAATCCGCCTTCACGGGTT
ATCCTTGTGGCTGCGCGCCGATCTTGATCTTCTGGTCGCCCGCACCGCCGGACGAACCCACCGGCCGCTGCTCAATAACG
GCGACGCGCGCGAAAAACTGGCCGAGCTGATGGCCAAGCGTCATCCTGTCTATGCCGAGGCCGATATCGTTTTCGATGCC
CTTGACGAAAGCCAGGACGCCTCCGCCCTGCGGGTGCGCTCGTGCCTTCTTTCCTACCTCGCCGACCATGCGGAGACCGC
CCCGTGA

Upstream 100 bases:

>100_bases
GAGGAAGGCAGTGTACCGGCTCCGTCGCGGGCGATCAACGTCGCCCGCCGTCCGTATCCGCGCCCCTCGTCGGGGGGTGG
CGATGAGAGGGATTGGCCGA

Downstream 100 bases:

>100_bases
GCCCAGACACAGCCGCCGATGCCGCCGCCGACCCCGCCTTGCAGTCGTCCGTTCTGACCGTTTCCCTGGGCGAGCGCAGC
TATCCCATTCATATCGGCCC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MIEAEENTLALPRTLVLVGLMGAGKTCIGRRLAQMAGVPFVDADVEIERAAKRTIAEIFATYGESEFRALERRVMARLLA
GRTCVLATGGGAFMAEDTRALIRLHGLSLWLRADLDLLVARTAGRTHRPLLNNGDAREKLAELMAKRHPVYAEADIVFDA
LDESQDASALRVRSCLLSYLADHAETAP

Sequences:

>Translated_188_residues
MIEAEENTLALPRTLVLVGLMGAGKTCIGRRLAQMAGVPFVDADVEIERAAKRTIAEIFATYGESEFRALERRVMARLLA
GRTCVLATGGGAFMAEDTRALIRLHGLSLWLRADLDLLVARTAGRTHRPLLNNGDAREKLAELMAKRHPVYAEADIVFDA
LDESQDASALRVRSCLLSYLADHAETAP
>Mature_188_residues
MIEAEENTLALPRTLVLVGLMGAGKTCIGRRLAQMAGVPFVDADVEIERAAKRTIAEIFATYGESEFRALERRVMARLLA
GRTCVLATGGGAFMAEDTRALIRLHGLSLWLRADLDLLVARTAGRTHRPLLNNGDAREKLAELMAKRHPVYAEADIVFDA
LDESQDASALRVRSCLLSYLADHAETAP

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=172, Percent_Identity=36.6279069767442, Blast_Score=101, Evalue=2e-23,
Organism=Escherichia coli, GI1786587, Length=166, Percent_Identity=33.1325301204819, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_RHORT (Q2RMW1)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428821.1
- ProteinModelPortal:   Q2RMW1
- SMR:   Q2RMW1
- STRING:   Q2RMW1
- GeneID:   3837197
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3740
- NMPDR:   fig|1085.1.peg.1174
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- PhylomeDB:   Q2RMW1
- ProtClustDB:   CLSK2397428
- BioCyc:   RRUB269796:RRU_A3740-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20516; Mature: 20516

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 44-44 BINDING 68-68 BINDING 90-90 BINDING 128-128 BINDING 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEAEENTLALPRTLVLVGLMGAGKTCIGRRLAQMAGVPFVDADVEIERAAKRTIAEIFA
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TYGESEFRALERRVMARLLAGRTCVLATGGGAFMAEDTRALIRLHGLSLWLRADLDLLVA
HHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCHHHHHH
RTAGRTHRPLLNNGDAREKLAELMAKRHPVYAEADIVFDALDESQDASALRVRSCLLSYL
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ADHAETAP
HHHCCCCC
>Mature Secondary Structure
MIEAEENTLALPRTLVLVGLMGAGKTCIGRRLAQMAGVPFVDADVEIERAAKRTIAEIFA
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TYGESEFRALERRVMARLLAGRTCVLATGGGAFMAEDTRALIRLHGLSLWLRADLDLLVA
HHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCHHHHHH
RTAGRTHRPLLNNGDAREKLAELMAKRHPVYAEADIVFDALDESQDASALRVRSCLLSYL
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ADHAETAP
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA