Click here to switch to the map view.

The map label for this gene is holA

Identifier: 83594958

GI number: 83594958

Start: 4169445

End: 4170473

Strand: Reverse

Name: holA

Synonym: Rru_A3629

Alternate gene names: NA

Gene position: 4170473-4169445 (Counterclockwise)

Preceding gene: 83594959

Following gene: 83594951

Centisome position: 95.81

GC content: 70.55

Gene sequence:

>1029_bases
GTGAAACTGACCGGCCAAGCCATCGACGGCTTCCTGCGCAAGCCCGATCCGAAAATCCGCTGCGTGCTGGTTTATGGCCC
CGACGAGGGGCTGGTGCGCGAGCGGCTGGAGCAGCTGGCGCGCACGGTGGTCGCCGATCCCAAGGACCCCTTCCGCATCA
CCGACCTGTCGGGCGACGATCTGCGCGCCGATCCGGCGCGGCTGGCCGACGAGGCGGCGGCCCTGGCCTTTGGCGGCGGG
CGGCGGCTGGTGCGTCTGCGTCAGATGACCGACCAGCACGCCCCGCGCCTTAAGGCCTTCGTCGAAGCCCCGGTTGGCGA
GGCCCTGGTGCTGGTCCAGGGCGGCGATCTCACGGCCCGCTCCGCCCTGCGCAAGCTGTTCGAAGGGGCTAGCGCCGCCG
CCGCCCTGCCCTGCTACGCCGATGAGGGGCGGTCGCTTGAGACCCTGGTGCGCGCCACCCTGGCCGAGGCCCGGCTGGCC
GCCGCCCCCGAGGTGATCGACTATCTGGTGGCCAATCTGGGCGGCGATCGCGGGGTCAGCCGCTCGGAACTGGCCAAGCT
GGTGACCTATTGCGGCAAGGCCACCAGCGTGTCCCTGGACGACGCCCTGGCCTGCGTGGGCGATAGCGCCCAGATCGGCC
TTGATATGCTGACCAACGCCGTGGCCGAGGGCGATAGCGCCACCGCCTTGCGCGCCCTTGACCGCCTGGGTCAGGAAGGC
ATGGCGACGGTCGCCCTTCTGCGGGGCCTGACCCGCCACTTCACCCGGCTGCATCTGGTCGCCGGACTGATCGCCGGGGG
AACGAGCGTGGATCAGGCCCTGGCCGCGCTCAAGCCGCCGGTGATGTTCAAACTGGCCCCGCGATTCCGCAGCCAAGTTC
AGCGCTGGTCAGCCGAGCGCCTTGCCCAGGCCCTGGATCTGTTGCTTGACGCCGAAATCGACGCGAAGAGCAGCGGCCTG
CCCGAGCGCGCCCTGGTGGAACGTCTGTTGCTGCGTCTGGCCCGGGGGGCAAAAACCGCCAGCCGCTGA

Upstream 100 bases:

>100_bases
GCCGCACCGCCGAACAGATCGCCGATCAGCTTTACACCCGCCTTGGCGCCTATTTCTCGCAAGCCCCGGCTCCGGCCGGC
CGGGTTCTTTAGCCGCGCCC

Downstream 100 bases:

>100_bases
AGAGGACGCCCTTGGCCTCGATCCGCGGGACGGATGTCCGCCCCCTTGCTTTCGTGAATGGGTATTTCTTTGTTTTTTCA
ACAGGTTCCGCAGGTCCAAG

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKLTGQAIDGFLRKPDPKIRCVLVYGPDEGLVRERLEQLARTVVADPKDPFRITDLSGDDLRADPARLADEAAALAFGGG
RRLVRLRQMTDQHAPRLKAFVEAPVGEALVLVQGGDLTARSALRKLFEGASAAAALPCYADEGRSLETLVRATLAEARLA
AAPEVIDYLVANLGGDRGVSRSELAKLVTYCGKATSVSLDDALACVGDSAQIGLDMLTNAVAEGDSATALRALDRLGQEG
MATVALLRGLTRHFTRLHLVAGLIAGGTSVDQALAALKPPVMFKLAPRFRSQVQRWSAERLAQALDLLLDAEIDAKSSGL
PERALVERLLLRLARGAKTASR

Sequences:

>Translated_342_residues
MKLTGQAIDGFLRKPDPKIRCVLVYGPDEGLVRERLEQLARTVVADPKDPFRITDLSGDDLRADPARLADEAAALAFGGG
RRLVRLRQMTDQHAPRLKAFVEAPVGEALVLVQGGDLTARSALRKLFEGASAAAALPCYADEGRSLETLVRATLAEARLA
AAPEVIDYLVANLGGDRGVSRSELAKLVTYCGKATSVSLDDALACVGDSAQIGLDMLTNAVAEGDSATALRALDRLGQEG
MATVALLRGLTRHFTRLHLVAGLIAGGTSVDQALAALKPPVMFKLAPRFRSQVQRWSAERLAQALDLLLDAEIDAKSSGL
PERALVERLLLRLARGAKTASR
>Mature_342_residues
MKLTGQAIDGFLRKPDPKIRCVLVYGPDEGLVRERLEQLARTVVADPKDPFRITDLSGDDLRADPARLADEAAALAFGGG
RRLVRLRQMTDQHAPRLKAFVEAPVGEALVLVQGGDLTARSALRKLFEGASAAAALPCYADEGRSLETLVRATLAEARLA
AAPEVIDYLVANLGGDRGVSRSELAKLVTYCGKATSVSLDDALACVGDSAQIGLDMLTNAVAEGDSATALRALDRLGQEG
MATVALLRGLTRHFTRLHLVAGLIAGGTSVDQALAALKPPVMFKLAPRFRSQVQRWSAERLAQALDLLLDAEIDAKSSGL
PERALVERLLLRLARGAKTASR

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921 [H]

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 36432; Mature: 36432

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00177 TOPOISOMERASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTGQAIDGFLRKPDPKIRCVLVYGPDEGLVRERLEQLARTVVADPKDPFRITDLSGDD
CCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
LRADPARLADEAAALAFGGGRRLVRLRQMTDQHAPRLKAFVEAPVGEALVLVQGGDLTAR
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEECCCHHHH
SALRKLFEGASAAAALPCYADEGRSLETLVRATLAEARLAAAPEVIDYLVANLGGDRGVS
HHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
RSELAKLVTYCGKATSVSLDDALACVGDSAQIGLDMLTNAVAEGDSATALRALDRLGQEG
HHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHH
MATVALLRGLTRHFTRLHLVAGLIAGGTSVDQALAALKPPVMFKLAPRFRSQVQRWSAER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHEEECHHHHHHHHHHHHHH
LAQALDLLLDAEIDAKSSGLPERALVERLLLRLARGAKTASR
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLTGQAIDGFLRKPDPKIRCVLVYGPDEGLVRERLEQLARTVVADPKDPFRITDLSGDD
CCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
LRADPARLADEAAALAFGGGRRLVRLRQMTDQHAPRLKAFVEAPVGEALVLVQGGDLTAR
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEECCCHHHH
SALRKLFEGASAAAALPCYADEGRSLETLVRATLAEARLAAAPEVIDYLVANLGGDRGVS
HHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
RSELAKLVTYCGKATSVSLDDALACVGDSAQIGLDMLTNAVAEGDSATALRALDRLGQEG
HHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHH
MATVALLRGLTRHFTRLHLVAGLIAGGTSVDQALAALKPPVMFKLAPRFRSQVQRWSAER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHEEECHHHHHHHHHHHHHH
LAQALDLLLDAEIDAKSSGLPERALVERLLLRLARGAKTASR
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]