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The map label for this gene is aer [H]

Identifier: 83594793

GI number: 83594793

Start: 3989302

End: 3989826

Strand: Direct

Name: aer [H]

Synonym: Rru_A3464

Alternate gene names: 83594793

Gene position: 3989302-3989826 (Clockwise)

Preceding gene: 83594792

Following gene: 83594794

Centisome position: 91.65

GC content: 51.81

Gene sequence:

>525_bases
ATGGCCCGTCCCGTTATTGTTCCCACCGGAGTAGAGCGGTTTTTTGGAGAAGACGAGATTATCGTCTCCAAAACCGATCC
TCGTGGGGTGATCGTTTACGCCAACAAGATCTTTCTCGATATCGCCGGATATTGCGAGAAAGAGGTCGTCGGTCAGCCTC
ATAATATACTGCGCCATCCGGGCACGCCGTCATCCATTTTCAAGCTGATGTGGGATCGCATCCAAGCGGGAAATGAGGTC
TTCGCTTATGTTTGTAACATGGCAAAAAACGGCGATCACTACTGGGTTCTGGCCCATATCACCCCGTCTTTTAGCGCCGA
TGGCGCGATCACCGGTTACCATTCCAACCGCCGGGCGCCCGAGACGCGAATCCTTCCTGAAATAAAGGATCTCTACAACC
GTCTGTTGACGGAAGAAGAAACCGCTGGATCCCCCAAGAATCGTATCTTCGCCGGAATGAACTTCATCGATCGCATGCTC
GGTCAAAGGGGGGTGAGTTATGATCGCTTTATCCACAGTCTCTAA

Upstream 100 bases:

>100_bases
CCGTAATGTTGACAGGATTAAGCCTCTGTGCGGTTCCTGCGCATAGGGCTGAAAGGGTGTCCTTCGTCTCGAGGGCCCTC
GTCCCTTGACCGGAGGCTTC

Downstream 100 bases:

>100_bases
GCTCACCCTGTGCGGGGTGCTTACCGTGGTTTTGGGCGGGGCGGTGGCGAGCCTCGCCGTGGCCTCGAACGACTGGCTTG
ATCTTGGGCTGGCCGGCGGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MARPVIVPTGVERFFGEDEIIVSKTDPRGVIVYANKIFLDIAGYCEKEVVGQPHNILRHPGTPSSIFKLMWDRIQAGNEV
FAYVCNMAKNGDHYWVLAHITPSFSADGAITGYHSNRRAPETRILPEIKDLYNRLLTEEETAGSPKNRIFAGMNFIDRML
GQRGVSYDRFIHSL

Sequences:

>Translated_174_residues
MARPVIVPTGVERFFGEDEIIVSKTDPRGVIVYANKIFLDIAGYCEKEVVGQPHNILRHPGTPSSIFKLMWDRIQAGNEV
FAYVCNMAKNGDHYWVLAHITPSFSADGAITGYHSNRRAPETRILPEIKDLYNRLLTEEETAGSPKNRIFAGMNFIDRML
GQRGVSYDRFIHSL
>Mature_173_residues
ARPVIVPTGVERFFGEDEIIVSKTDPRGVIVYANKIFLDIAGYCEKEVVGQPHNILRHPGTPSSIFKLMWDRIQAGNEVF
AYVCNMAKNGDHYWVLAHITPSFSADGAITGYHSNRRAPETRILPEIKDLYNRLLTEEETAGSPKNRIFAGMNFIDRMLG
QRGVSYDRFIHSL

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=139, Percent_Identity=35.9712230215827, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 19685; Mature: 19554

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPVIVPTGVERFFGEDEIIVSKTDPRGVIVYANKIFLDIAGYCEKEVVGQPHNILRHP
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEEECEEEEEHHHHHHHHHCCCCHHHHCCC
GTPSSIFKLMWDRIQAGNEVFAYVCNMAKNGDHYWVLAHITPSFSADGAITGYHSNRRAP
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEECCCCCCCCC
ETRILPEIKDLYNRLLTEEETAGSPKNRIFAGMNFIDRMLGQRGVSYDRFIHSL
CHHCCHHHHHHHHHHHCCCCCCCCCCHHEEECHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure 
ARPVIVPTGVERFFGEDEIIVSKTDPRGVIVYANKIFLDIAGYCEKEVVGQPHNILRHP
CCCCCCCCCHHHHCCCCCEEEECCCCCEEEEEECEEEEEHHHHHHHHHCCCCHHHHCCC
GTPSSIFKLMWDRIQAGNEVFAYVCNMAKNGDHYWVLAHITPSFSADGAITGYHSNRRAP
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEECCCCCCCCC
ETRILPEIKDLYNRLLTEEETAGSPKNRIFAGMNFIDRMLGQRGVSYDRFIHSL
CHHCCHHHHHHHHHHHCCCCCCCCCCHHEEECHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]