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The map label for this gene is divL [H]

Identifier: 83594772

GI number: 83594772

Start: 3964898

End: 3967303

Strand: Reverse

Name: divL [H]

Synonym: Rru_A3443

Alternate gene names: 83594772

Gene position: 3967303-3964898 (Counterclockwise)

Preceding gene: 83594773

Following gene: 83594771

Centisome position: 91.14

GC content: 68.7

Gene sequence:

>2406_bases
ATGTTTTCGGACCCCTCCTTCGCCGATTCCGTTCTGCCGACCCAGATCGGAACCCTCATCGTCCTGGTCGCCGGGACGGT
CGCCGTCCTGATGGGCGGGCTGGCCCTGCGCTGGCGCTCGGCTTGGCTGCGCAGCCTGGAGAGCCGCCATCAGGCCGAAT
ACGAAGCCGAGGCCCTGCGCGAGATCCTGGCCACCGCCAGCGATGGCTATTACCTGTGGGCGCTTGACGGGCCGTTGCGT
GGACGCGAGTTCTGTTCGCGCCGGCTGGCGGTGCTGTTGCGCCTGCCCTCGGGCGTCAATGCCGAGCTGAAGGAAATCAT
CGGCGTTTTCGCCGAAGGCGACGCCCAGGCCCTCGAAGGCATGATCGCCGTGCTGCGCCGCGAGGGCCGGGGCTTCGTTC
TTGACCTTTTGCTCGCCGCCAGCGGTCGGCGGGTGCGCACCGTCGGCATCCGCGCCAACGCCGGCGACGGCCACGCCCTG
GCCGATCTGCTGTGGATGCGCGACGTGACCGAGGAAACCCGGGTTGGCGATGTGCAAGGCCGCCGCGCCCAGGCCCTGCA
GGCCGAACGCGACCGCCTGCGCGCCGTGGTCGACGCCCTGCCGGCGCCGATCTGGACCCGCGACGACAGTCTGGCCATTG
GCGATGGCAATACGGCGCTGGCCCGGGCCCTTGACCTGGGGTCGGCCGGCGATGCCTTGACGGCGCGCCGCGAACTCGCC
CCCGGGGCCACCGGTCAGGAAATGCGCGCCCTGGCGGCGCGTAGCCGGGCGGCCGGACGCCCGGCCCGCGCCCGCTTCCA
CGCCGTGCTCGACGGCGAGCGCAAGCTGCTGGAAATCACCGAGACGCCCTTGTCCGAGGGACCCTTGCGCGGTCACACGG
TTGGCATCGCCCAGGACATCACGCCGATCGAAGAGGTTGAAAGCCGCCTGGAGCGCGAGACCGAGGCCCATGCCGAGGTG
CTTGAGCGCCTGGGCTCGGCCATCGCCATCTTCGGCGGCGATACCCGCTTGTCGTTCCACAACGCCGCCTTCGCCAGCCT
GTGGGGGCTCGAGTCCGATTGGCTCAACGGCGAGCCGTCCTATGGCGATTTCCTTGAACGCCAGCGCGAAAACCGCCGCC
TGCCCGAGGTCGCCGATTTCCCGGCCTATAAGGCCGGCGAACTGGGCTATTTCACCAAGCTTCTGCGCCCGCGCGAAGAC
ATCTTGCACCTGCCCGACGGCGCCACTCTGCGCCGGGTGATCGCCCCCCATCCGCTGGGCGGGCTGATCACCACCTTCGA
GGATGTCACCGACAGTCTGGCCCTGGAACGCTCCTACAACCAGCTGACCGCCGTGCAGCGCGAGACCATCGACCACCTGC
ACGAGGCGGTCGCCGTCTTTGGCGCCAATGGCCGGCTGCGCCTGTCCAATCCGGCCTTCTCCCAGCTGTGGAGCGGCGCC
GGTACCGACAGCGAGCCCCAGGCCGCCGCCCTGCTTGACGACATGGAGGCGGCGATGATCGCCGATGGCGCCTGGGAAAC
CTTCCGCCGCCGGCTCTGCGTTCGCGACGAAAGCGCCGGTCCGCGCAACGGCCGGCTGGTGCGCCGCGACGGCCGCCATC
TTGATTACGCCACCGTGCCGCTGCCCGATGGCGGGTTGTTGCTGTCGATCCTCGACATCACCGACCGGGTGCGGGTGGAA
CAGGCCTTGAGCGAACGCACCGAGGCCCTGCGCGCCGCCGATATGATGAAAAGCGAATTCATCGCCAATGTGTCTTATGA
ATTGCGCACGCCGCTGACCACCATCTCGGGCTTTTCCGAGATCCTGTCGGGGGCCTATTACGGCGAGCTCAATACCCGTC
AGCGCGAATACGCCGAGGTGATCACCGAAACCTCGCGCCAAGTGGTGCGGTTGATCGACGAGATCACCGATCTGGTCAGC
ATGCAGGCCGGCAAGCTGGCCCTGGAACTTGACGCCTTCGACATCCACGCCGCCCTGGCCGCCGTGCTGGCCCTGGGCCG
CGAATCGGCGCGGCGCCGGGGCGTCACCTTGAATTTCGACTGCCCGCCCGATGCCGGCTGGATGGTCGCTGACGAAACCC
GCATCAAGCAGATCCTCTTCCACCTGATGTCGAACGCCATCACCGGCACCGACGCCGGCGGTCAGGTGACCCTGGCCGTG
CAACGCGAGGACACCCCCGACGGCGGCACCATGGTGTTCACCGTCGCCGATACCGGACGCGGCATGGACGAGATCTTGCA
AACCCGCGCCTTTGAAAGCTTCGCCAAGGGCCCGCGCGCCGATGGCGCCGGCCTGGGGCTGGCCCTGGTGCGCCGCTTCG
TCGAACTCCACGGCGGCGCCGTCGATTTGGTCAGCGTGCCCGGCGAAGGCACCACCGTCACCGTCCGCATCCCCACCTCG
GGCTGA

Upstream 100 bases:

>100_bases
ATCGGCGGGGCGCCGCGCCCTCGTCCGAAGCCGCTTGCATTTTCCGTAACGCCCGGCCACGCTTCCCGCCCTTTTCCCGC
TTCGGCGATGGCCCCTTCCC

Downstream 100 bases:

>100_bases
GGGCGGCGGCGTGAAGCGGCGGCGGCCGCCGCCCTCCTTTTAAAAGGGGTCAGATGCGGTAATGGGCCTTGGCCAGGAGT
CTAGCCAGGCAAGGTGGCCA

Product: PAS/PAC sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 801

Protein sequence:

>801_residues
MFSDPSFADSVLPTQIGTLIVLVAGTVAVLMGGLALRWRSAWLRSLESRHQAEYEAEALREILATASDGYYLWALDGPLR
GREFCSRRLAVLLRLPSGVNAELKEIIGVFAEGDAQALEGMIAVLRREGRGFVLDLLLAASGRRVRTVGIRANAGDGHAL
ADLLWMRDVTEETRVGDVQGRRAQALQAERDRLRAVVDALPAPIWTRDDSLAIGDGNTALARALDLGSAGDALTARRELA
PGATGQEMRALAARSRAAGRPARARFHAVLDGERKLLEITETPLSEGPLRGHTVGIAQDITPIEEVESRLERETEAHAEV
LERLGSAIAIFGGDTRLSFHNAAFASLWGLESDWLNGEPSYGDFLERQRENRRLPEVADFPAYKAGELGYFTKLLRPRED
ILHLPDGATLRRVIAPHPLGGLITTFEDVTDSLALERSYNQLTAVQRETIDHLHEAVAVFGANGRLRLSNPAFSQLWSGA
GTDSEPQAAALLDDMEAAMIADGAWETFRRRLCVRDESAGPRNGRLVRRDGRHLDYATVPLPDGGLLLSILDITDRVRVE
QALSERTEALRAADMMKSEFIANVSYELRTPLTTISGFSEILSGAYYGELNTRQREYAEVITETSRQVVRLIDEITDLVS
MQAGKLALELDAFDIHAALAAVLALGRESARRRGVTLNFDCPPDAGWMVADETRIKQILFHLMSNAITGTDAGGQVTLAV
QREDTPDGGTMVFTVADTGRGMDEILQTRAFESFAKGPRADGAGLGLALVRRFVELHGGAVDLVSVPGEGTTVTVRIPTS
G

Sequences:

>Translated_801_residues
MFSDPSFADSVLPTQIGTLIVLVAGTVAVLMGGLALRWRSAWLRSLESRHQAEYEAEALREILATASDGYYLWALDGPLR
GREFCSRRLAVLLRLPSGVNAELKEIIGVFAEGDAQALEGMIAVLRREGRGFVLDLLLAASGRRVRTVGIRANAGDGHAL
ADLLWMRDVTEETRVGDVQGRRAQALQAERDRLRAVVDALPAPIWTRDDSLAIGDGNTALARALDLGSAGDALTARRELA
PGATGQEMRALAARSRAAGRPARARFHAVLDGERKLLEITETPLSEGPLRGHTVGIAQDITPIEEVESRLERETEAHAEV
LERLGSAIAIFGGDTRLSFHNAAFASLWGLESDWLNGEPSYGDFLERQRENRRLPEVADFPAYKAGELGYFTKLLRPRED
ILHLPDGATLRRVIAPHPLGGLITTFEDVTDSLALERSYNQLTAVQRETIDHLHEAVAVFGANGRLRLSNPAFSQLWSGA
GTDSEPQAAALLDDMEAAMIADGAWETFRRRLCVRDESAGPRNGRLVRRDGRHLDYATVPLPDGGLLLSILDITDRVRVE
QALSERTEALRAADMMKSEFIANVSYELRTPLTTISGFSEILSGAYYGELNTRQREYAEVITETSRQVVRLIDEITDLVS
MQAGKLALELDAFDIHAALAAVLALGRESARRRGVTLNFDCPPDAGWMVADETRIKQILFHLMSNAITGTDAGGQVTLAV
QREDTPDGGTMVFTVADTGRGMDEILQTRAFESFAKGPRADGAGLGLALVRRFVELHGGAVDLVSVPGEGTTVTVRIPTS
G
>Mature_801_residues
MFSDPSFADSVLPTQIGTLIVLVAGTVAVLMGGLALRWRSAWLRSLESRHQAEYEAEALREILATASDGYYLWALDGPLR
GREFCSRRLAVLLRLPSGVNAELKEIIGVFAEGDAQALEGMIAVLRREGRGFVLDLLLAASGRRVRTVGIRANAGDGHAL
ADLLWMRDVTEETRVGDVQGRRAQALQAERDRLRAVVDALPAPIWTRDDSLAIGDGNTALARALDLGSAGDALTARRELA
PGATGQEMRALAARSRAAGRPARARFHAVLDGERKLLEITETPLSEGPLRGHTVGIAQDITPIEEVESRLERETEAHAEV
LERLGSAIAIFGGDTRLSFHNAAFASLWGLESDWLNGEPSYGDFLERQRENRRLPEVADFPAYKAGELGYFTKLLRPRED
ILHLPDGATLRRVIAPHPLGGLITTFEDVTDSLALERSYNQLTAVQRETIDHLHEAVAVFGANGRLRLSNPAFSQLWSGA
GTDSEPQAAALLDDMEAAMIADGAWETFRRRLCVRDESAGPRNGRLVRRDGRHLDYATVPLPDGGLLLSILDITDRVRVE
QALSERTEALRAADMMKSEFIANVSYELRTPLTTISGFSEILSGAYYGELNTRQREYAEVITETSRQVVRLIDEITDLVS
MQAGKLALELDAFDIHAALAAVLALGRESARRRGVTLNFDCPPDAGWMVADETRIKQILFHLMSNAITGTDAGGQVTLAV
QREDTPDGGTMVFTVADTGRGMDEILQTRAFESFAKGPRADGAGLGLALVRRFVELHGGAVDLVSVPGEGTTVTVRIPTS
G

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=31.390134529148, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=32.0158102766798, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=29.8449612403101, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=29.9212598425197, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=29.6703296703297, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1786600, Length=298, Percent_Identity=28.5234899328859, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=27.4774774774775, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=31.1203319502075, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1788549, Length=257, Percent_Identity=25.2918287937743, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=24.5614035087719, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=25.1028806584362, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=277, Percent_Identity=26.7148014440433, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790300, Length=268, Percent_Identity=25.7462686567164, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87112; Mature: 87112

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSDPSFADSVLPTQIGTLIVLVAGTVAVLMGGLALRWRSAWLRSLESRHQAEYEAEALR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EILATASDGYYLWALDGPLRGREFCSRRLAVLLRLPSGVNAELKEIIGVFAEGDAQALEG
HHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHH
MIAVLRREGRGFVLDLLLAASGRRVRTVGIRANAGDGHALADLLWMRDVTEETRVGDVQG
HHHHHHHCCCCHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
RRAQALQAERDRLRAVVDALPAPIWTRDDSLAIGDGNTALARALDLGSAGDALTARRELA
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCHHHHHHHCCCCCCCHHHHHHHCC
PGATGQEMRALAARSRAAGRPARARFHAVLDGERKLLEITETPLSEGPLRGHTVGIAQDI
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHEEEEECCCCCCCCCCCCEEECHHCC
TPIEEVESRLERETEAHAEVLERLGSAIAIFGGDTRLSFHNAAFASLWGLESDWLNGEPS
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEHHHHHHHHHCCCCCCCCCCCC
YGDFLERQRENRRLPEVADFPAYKAGELGYFTKLLRPREDILHLPDGATLRRVIAPHPLG
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHEECCCCHHHHHHHCCCCCC
GLITTFEDVTDSLALERSYNQLTAVQRETIDHLHEAVAVFGANGRLRLSNPAFSQLWSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCC
GTDSEPQAAALLDDMEAAMIADGAWETFRRRLCVRDESAGPRNGRLVRRDGRHLDYATVP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEC
LPDGGLLLSILDITDRVRVEQALSERTEALRAADMMKSEFIANVSYELRTPLTTISGFSE
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHH
ILSGAYYGELNTRQREYAEVITETSRQVVRLIDEITDLVSMQAGKLALELDAFDIHAALA
HHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHH
AVLALGRESARRRGVTLNFDCPPDAGWMVADETRIKQILFHLMSNAITGTDAGGQVTLAV
HHHHHHHHHHHHCCCEEEECCCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
QREDTPDGGTMVFTVADTGRGMDEILQTRAFESFAKGPRADGAGLGLALVRRFVELHGGA
EECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCE
VDLVSVPGEGTTVTVRIPTSG
EEEEECCCCCCEEEEEECCCC
>Mature Secondary Structure
MFSDPSFADSVLPTQIGTLIVLVAGTVAVLMGGLALRWRSAWLRSLESRHQAEYEAEALR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EILATASDGYYLWALDGPLRGREFCSRRLAVLLRLPSGVNAELKEIIGVFAEGDAQALEG
HHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHH
MIAVLRREGRGFVLDLLLAASGRRVRTVGIRANAGDGHALADLLWMRDVTEETRVGDVQG
HHHHHHHCCCCHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
RRAQALQAERDRLRAVVDALPAPIWTRDDSLAIGDGNTALARALDLGSAGDALTARRELA
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCHHHHHHHCCCCCCCHHHHHHHCC
PGATGQEMRALAARSRAAGRPARARFHAVLDGERKLLEITETPLSEGPLRGHTVGIAQDI
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHEEEEECCCCCCCCCCCCEEECHHCC
TPIEEVESRLERETEAHAEVLERLGSAIAIFGGDTRLSFHNAAFASLWGLESDWLNGEPS
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEHHHHHHHHHCCCCCCCCCCCC
YGDFLERQRENRRLPEVADFPAYKAGELGYFTKLLRPREDILHLPDGATLRRVIAPHPLG
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHEECCCCHHHHHHHCCCCCC
GLITTFEDVTDSLALERSYNQLTAVQRETIDHLHEAVAVFGANGRLRLSNPAFSQLWSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCC
GTDSEPQAAALLDDMEAAMIADGAWETFRRRLCVRDESAGPRNGRLVRRDGRHLDYATVP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEC
LPDGGLLLSILDITDRVRVEQALSERTEALRAADMMKSEFIANVSYELRTPLTTISGFSE
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHH
ILSGAYYGELNTRQREYAEVITETSRQVVRLIDEITDLVSMQAGKLALELDAFDIHAALA
HHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHH
AVLALGRESARRRGVTLNFDCPPDAGWMVADETRIKQILFHLMSNAITGTDAGGQVTLAV
HHHHHHHHHHHHCCCEEEECCCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
QREDTPDGGTMVFTVADTGRGMDEILQTRAFESFAKGPRADGAGLGLALVRRFVELHGGA
EECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCE
VDLVSVPGEGTTVTVRIPTSG
EEEEECCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]