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The map label for this gene is lasR [H]

Identifier: 83594724

GI number: 83594724

Start: 3912592

End: 3913374

Strand: Direct

Name: lasR [H]

Synonym: Rru_A3395

Alternate gene names: 83594724

Gene position: 3912592-3913374 (Clockwise)

Preceding gene: 83594722

Following gene: 83594725

Centisome position: 89.89

GC content: 61.69

Gene sequence:

>783_bases
ATGATGTCTGGCGGCGACGATATTCTTGGGTCTTTTCTAGAAGCTCTCAATGGCACCTCCGACAGCGCCGATCTGACGAC
GTTACTGACCGGTACCTTCGCCAGGCTGGGCTTTCCCCATTCCTGTTATCACGTGGTCCGCCTTGAAGGCGCGGGCGCCC
GCCTGCCCTATGTTCTGCACAACTACAAGGACTCGTGGAGCGAACACTACTTCCGCGAGGGCTTCCTTGAGATCGATCCC
GTCTTGGCCACCTGTCCCGACCGTCAGCTTCCCTTCCTGTGGTCCGAGGCGATCGCACCCGAGTCCCTCAGCCACGATCA
ACGCCGGATGTTTTCCGACGCCCGGGATGCCGGATTGCACGACGGCTATTCGGTGCCGATTCGCGGCAGTCACGGCGAAT
TCGCCACGGTGACGGTGATCCCCGAACAAGGCGGCGACGCCGCCCGCCGGCTGATCGGCGAGCAAAAGCACCTTGTGCAT
CTGTTGGCGCTTTATTTCGACCGCCATGCCCGCAGCACGGTGATCAACGCCCGGCTGTCGTCACGTCGGCGCAAGACCGT
GCTGTCCCCACGCGAGCAGGAGATGCTGCGCTGGGCGGCGCTCGGCAAGACCTCGTGGGAAATCGCCGAAATCGCCGGAA
TTTCGACGAAAAGCGTCGAGTTTCACCTGGATAACGCCAAAAAGAAGCTGGGGACCTATTCCAAGACCCACGCCGTGGTC
AAGGCCCTGACCCTGGGGCTGGTCACCATGGATGGCCTTGCCGAGCCTTCTTCGCGCGGATAA

Upstream 100 bases:

>100_bases
TCTTCCACCTAGTAAAAACACCGGGATCTGGCGTTCCCCGCATCAAAGGCGCATGATCTAAAAACAAACAAGCGAGATAT
CATGAAAGGGGGCGGGAGAG

Downstream 100 bases:

>100_bases
TAAACCCCGTTTTTTCCGGGCGGGAGGGGGACGGTCTATCATCGTACCCCTGGGAAAACCCCGGGGGGGACAATCCCCGG
ACGTCCTGCCCAGGATTTCT

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MMSGGDDILGSFLEALNGTSDSADLTTLLTGTFARLGFPHSCYHVVRLEGAGARLPYVLHNYKDSWSEHYFREGFLEIDP
VLATCPDRQLPFLWSEAIAPESLSHDQRRMFSDARDAGLHDGYSVPIRGSHGEFATVTVIPEQGGDAARRLIGEQKHLVH
LLALYFDRHARSTVINARLSSRRRKTVLSPREQEMLRWAALGKTSWEIAEIAGISTKSVEFHLDNAKKKLGTYSKTHAVV
KALTLGLVTMDGLAEPSSRG

Sequences:

>Translated_260_residues
MMSGGDDILGSFLEALNGTSDSADLTTLLTGTFARLGFPHSCYHVVRLEGAGARLPYVLHNYKDSWSEHYFREGFLEIDP
VLATCPDRQLPFLWSEAIAPESLSHDQRRMFSDARDAGLHDGYSVPIRGSHGEFATVTVIPEQGGDAARRLIGEQKHLVH
LLALYFDRHARSTVINARLSSRRRKTVLSPREQEMLRWAALGKTSWEIAEIAGISTKSVEFHLDNAKKKLGTYSKTHAVV
KALTLGLVTMDGLAEPSSRG
>Mature_260_residues
MMSGGDDILGSFLEALNGTSDSADLTTLLTGTFARLGFPHSCYHVVRLEGAGARLPYVLHNYKDSWSEHYFREGFLEIDP
VLATCPDRQLPFLWSEAIAPESLSHDQRRMFSDARDAGLHDGYSVPIRGSHGEFATVTVIPEQGGDAARRLIGEQKHLVH
LLALYFDRHARSTVINARLSSRRRKTVLSPREQEMLRWAALGKTSWEIAEIAGISTKSVEFHLDNAKKKLGTYSKTHAVV
KALTLGLVTMDGLAEPSSRG

Specific function: Transcriptional activator of elastase structural gene (lasB). Binds to the PAI autoinducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR005143
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03472 Autoind_bind; PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 28760; Mature: 28760

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSGGDDILGSFLEALNGTSDSADLTTLLTGTFARLGFPHSCYHVVRLEGAGARLPYVLH
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCHHHH
NYKDSWSEHYFREGFLEIDPVLATCPDRQLPFLWSEAIAPESLSHDQRRMFSDARDAGLH
CCHHHHHHHHHHCCCEEECCHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
DGYSVPIRGSHGEFATVTVIPEQGGDAARRLIGEQKHLVHLLALYFDRHARSTVINARLS
CCCCCEEECCCCCEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRRRKTVLSPREQEMLRWAALGKTSWEIAEIAGISTKSVEFHLDNAKKKLGTYSKTHAVV
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECHHHHHHCCHHHHHHHH
KALTLGLVTMDGLAEPSSRG
HHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMSGGDDILGSFLEALNGTSDSADLTTLLTGTFARLGFPHSCYHVVRLEGAGARLPYVLH
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCHHHH
NYKDSWSEHYFREGFLEIDPVLATCPDRQLPFLWSEAIAPESLSHDQRRMFSDARDAGLH
CCHHHHHHHHHHCCCEEECCHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
DGYSVPIRGSHGEFATVTVIPEQGGDAARRLIGEQKHLVHLLALYFDRHARSTVINARLS
CCCCCEEECCCCCEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRRRKTVLSPREQEMLRWAALGKTSWEIAEIAGISTKSVEFHLDNAKKKLGTYSKTHAVV
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECHHHHHHCCHHHHHHHH
KALTLGLVTMDGLAEPSSRG
HHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1902216; 7937080; 10984043 [H]