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The map label for this gene is pbpG [H]

Identifier: 83594722

GI number: 83594722

Start: 3910206

End: 3912161

Strand: Direct

Name: pbpG [H]

Synonym: Rru_A3393

Alternate gene names: 83594722

Gene position: 3910206-3912161 (Clockwise)

Preceding gene: 83594717

Following gene: 83594724

Centisome position: 89.83

GC content: 69.17

Gene sequence:

>1956_bases
ATGGCTCGCAGACCCCAAACAGACCGCATGGCGCCCGTTTTCGAGGCCTCCGCCCCCTCCCGCCCGCCGCTGATCGCCGA
GCGGGTGGTGCCGGAGCTAAGCGACGACGCGCCCCGACGCGCCGCCCCCTCGCCGCGCCCGCCGCCCCGTCGCCGCAAGC
CCGGTCGCTCACCGGCGCGCAAGGCGCCGCGCCGGCCGCGGCGGCGGTGGGTTTGGCCGCTGATCCGCCTGATGCTGGTC
GGGGTGATCTGGATGGTGATCGGTCTGGCCGGGGTGGTCGTATGGTTCGGCCATGACCTGCCCGACCCGGTGACGTCGGC
CAATGTGACGCGGCGGCCCTCGGTGACGCTGCTTGCCGCCGATGGCAGCCAATTGGCCTCCTTTGGCGATATCCAGGGCG
ATACCGTGCGCACGAGCGACGTGCCCCGCGCCCTGGTTCTGGCGATTCTCGCCACCGAGGACCGGCGGTTCTTCAAGCAT
TTCGGCCTGGATCTGGTGGGTATCGCCCGCGCCAGCGTGGTCAACCTGCGGGCGGGGCGGGTGGTCCAGGGCGGATCGAC
GCTCACCCAGCAGGTCGCCAAGAACCTGTTCCTGACCCACGACCGCACCTTCAAACGCAAGATCCAGGAGGTCTTGCTGG
CGCTGTGGCTGGAACAAACCTTCACCAAGGACCAGATTCTCAGCCTTTATCTCAACCGCGTTTATCTGGGCGCGGGCACC
CACGGCGTCGATGCGGCGGCGCGGCGCTACTTCGACCAGCCGGTGGGGCAGATCAATCTTTACCAAGCGGCGTTGCTGGC
CGGGCTGCCCAAGGCGCCCTCGCGCCTGAACCCGGTGACCAATCCCGACGGATCGCGGGTTCGCACCCTTCAGGTGCTGC
AAAACATGGTCGAGGCCAAGATGATCACCCCGGCCCTGGCCAAACAGGCCGCGGCCTTGGCCGACGGGGCGATTCCCGGC
GCCCGGCGCGGCGGCATGGGCAGTTATTTCGCCGATTGGATCCTTGAGCGCGTCGATGATTTCGCCGGCCCCCGCGACCG
CGATCTGATCGTGCGAACCACCCTTGATCCGGTGCAGCAGCGCTCGGCCGAGGCGGCGGTGGCCGGGCTGCTCGCCGAAA
AAGGCGCGGCGATGAAGGCCAGTCAGGCCGCCCTGGTCGCCCTCGCCCCCGATGGCGCGGTGACGGCGATGGTGGGGGGG
CGCGATCACGCGACCAGCCCGTTCAACCGGGCGGCCCAGGCCCGCCGCCAGCCGGGCAGCGCCTTCAAGCCCTTCGTCTT
TCTGGCGGGGCTGGAAGCTGGGCTGACGCCCTCGACGATGATGGACGACGCGCCGATCACGGTGAACGGCTGGTCGCCGG
GCAATTACAAGGACAAATACAAGGGGCGGGTCAGCCTGACCCAGGCCTTCGCCCAGTCGCTCAATACGGTGGCGGTGCGG
GTGAGCGAAACCGCCGGGCGCGGCGCCGTGGTCAAGGTCGCCCATCGCCTGGGGGTTATCGGATCGCTCTCGCCCCTGCC
CTCGATCGCGCTCGGCGTCTTCGAGGTCTCGCCGCTGGATCTGACGGCGGCCTATGCCCCCTTCGCCAACGGCGGTTATG
CGGTGGTGCCCCACGGCATTCTGAGCATCGCCGATCGCGATGGCGGCCTGCTCTATGAACGCCAGGACAGCGGGCCGCGC
CGGGTTGTGGCGCCCGAACTCGCCCGGTCGATGGATACGATGCTAGGCGCCGTGGTGTCCTGGGGAACCGGACGGGCGGC
GGGGCTGCCCGATCGCACGGCGCGCGGCAAGACCGGAACCAGCCAGGGATACCGCGACGCTTGGTTCGTCGGCTATGCCG
GCAAAACCCTGGCCGGAGTCTGGGTCGGCAATGACGATGGCACGCCGATGCGCGATGTCACCGGCGGTATTCTGCCCACG
CAGATCTGGCATGCCTTCATGCTGAACGCCCCGTAA

Upstream 100 bases:

>100_bases
TCCTTGAACCCACAGGATAGAGACAAGCGGCAGGCGCTTCAAGGGGACCGTCGCCCTCATCGACGTCCCCCCCCAACGAC
GGTTTCCGCCAAGAATCGGC

Downstream 100 bases:

>100_bases
AGCCCCTCCCGAGGGATGGGATTACAGGCCGCGATCAAGAAGACTTTGGCGCGCCCGTTCCAAAAGGAAGGCGACCTCGG
GAAGATCCAGGGATTCGGCG

Product: penicillin-binding protein 1A

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MARRPQTDRMAPVFEASAPSRPPLIAERVVPELSDDAPRRAAPSPRPPPRRRKPGRSPARKAPRRPRRRWVWPLIRLMLV
GVIWMVIGLAGVVVWFGHDLPDPVTSANVTRRPSVTLLAADGSQLASFGDIQGDTVRTSDVPRALVLAILATEDRRFFKH
FGLDLVGIARASVVNLRAGRVVQGGSTLTQQVAKNLFLTHDRTFKRKIQEVLLALWLEQTFTKDQILSLYLNRVYLGAGT
HGVDAAARRYFDQPVGQINLYQAALLAGLPKAPSRLNPVTNPDGSRVRTLQVLQNMVEAKMITPALAKQAAALADGAIPG
ARRGGMGSYFADWILERVDDFAGPRDRDLIVRTTLDPVQQRSAEAAVAGLLAEKGAAMKASQAALVALAPDGAVTAMVGG
RDHATSPFNRAAQARRQPGSAFKPFVFLAGLEAGLTPSTMMDDAPITVNGWSPGNYKDKYKGRVSLTQAFAQSLNTVAVR
VSETAGRGAVVKVAHRLGVIGSLSPLPSIALGVFEVSPLDLTAAYAPFANGGYAVVPHGILSIADRDGGLLYERQDSGPR
RVVAPELARSMDTMLGAVVSWGTGRAAGLPDRTARGKTGTSQGYRDAWFVGYAGKTLAGVWVGNDDGTPMRDVTGGILPT
QIWHAFMLNAP

Sequences:

>Translated_651_residues
MARRPQTDRMAPVFEASAPSRPPLIAERVVPELSDDAPRRAAPSPRPPPRRRKPGRSPARKAPRRPRRRWVWPLIRLMLV
GVIWMVIGLAGVVVWFGHDLPDPVTSANVTRRPSVTLLAADGSQLASFGDIQGDTVRTSDVPRALVLAILATEDRRFFKH
FGLDLVGIARASVVNLRAGRVVQGGSTLTQQVAKNLFLTHDRTFKRKIQEVLLALWLEQTFTKDQILSLYLNRVYLGAGT
HGVDAAARRYFDQPVGQINLYQAALLAGLPKAPSRLNPVTNPDGSRVRTLQVLQNMVEAKMITPALAKQAAALADGAIPG
ARRGGMGSYFADWILERVDDFAGPRDRDLIVRTTLDPVQQRSAEAAVAGLLAEKGAAMKASQAALVALAPDGAVTAMVGG
RDHATSPFNRAAQARRQPGSAFKPFVFLAGLEAGLTPSTMMDDAPITVNGWSPGNYKDKYKGRVSLTQAFAQSLNTVAVR
VSETAGRGAVVKVAHRLGVIGSLSPLPSIALGVFEVSPLDLTAAYAPFANGGYAVVPHGILSIADRDGGLLYERQDSGPR
RVVAPELARSMDTMLGAVVSWGTGRAAGLPDRTARGKTGTSQGYRDAWFVGYAGKTLAGVWVGNDDGTPMRDVTGGILPT
QIWHAFMLNAP
>Mature_650_residues
ARRPQTDRMAPVFEASAPSRPPLIAERVVPELSDDAPRRAAPSPRPPPRRRKPGRSPARKAPRRPRRRWVWPLIRLMLVG
VIWMVIGLAGVVVWFGHDLPDPVTSANVTRRPSVTLLAADGSQLASFGDIQGDTVRTSDVPRALVLAILATEDRRFFKHF
GLDLVGIARASVVNLRAGRVVQGGSTLTQQVAKNLFLTHDRTFKRKIQEVLLALWLEQTFTKDQILSLYLNRVYLGAGTH
GVDAAARRYFDQPVGQINLYQAALLAGLPKAPSRLNPVTNPDGSRVRTLQVLQNMVEAKMITPALAKQAAALADGAIPGA
RRGGMGSYFADWILERVDDFAGPRDRDLIVRTTLDPVQQRSAEAAVAGLLAEKGAAMKASQAALVALAPDGAVTAMVGGR
DHATSPFNRAAQARRQPGSAFKPFVFLAGLEAGLTPSTMMDDAPITVNGWSPGNYKDKYKGRVSLTQAFAQSLNTVAVRV
SETAGRGAVVKVAHRLGVIGSLSPLPSIALGVFEVSPLDLTAAYAPFANGGYAVVPHGILSIADRDGGLLYERQDSGPRR
VVAPELARSMDTMLGAVVSWGTGRAAGLPDRTARGKTGTSQGYRDAWFVGYAGKTLAGVWVGNDDGTPMRDVTGGILPTQ
IWHAFMLNAP

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=536, Percent_Identity=36.3805970149254, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1788867, Length=584, Percent_Identity=31.8493150684932, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI87082258, Length=230, Percent_Identity=41.7391304347826, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI1789601, Length=226, Percent_Identity=34.9557522123894, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 69821; Mature: 69690

Theoretical pI: Translated: 11.11; Mature: 11.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRPQTDRMAPVFEASAPSRPPLIAERVVPELSDDAPRRAAPSPRPPPRRRKPGRSPAR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
KAPRRPRRRWVWPLIRLMLVGVIWMVIGLAGVVVWFGHDLPDPVTSANVTRRPSVTLLAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEC
DGSQLASFGDIQGDTVRTSDVPRALVLAILATEDRRFFKHFGLDLVGIARASVVNLRAGR
CCCHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCC
VVQGGSTLTQQVAKNLFLTHDRTFKRKIQEVLLALWLEQTFTKDQILSLYLNRVYLGAGT
EEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCC
HGVDAAARRYFDQPVGQINLYQAALLAGLPKAPSRLNPVTNPDGSRVRTLQVLQNMVEAK
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
MITPALAKQAAALADGAIPGARRGGMGSYFADWILERVDDFAGPRDRDLIVRTTLDPVQQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
RSAEAAVAGLLAEKGAAMKASQAALVALAPDGAVTAMVGGRDHATSPFNRAAQARRQPGS
HHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHCCCCC
AFKPFVFLAGLEAGLTPSTMMDDAPITVNGWSPGNYKDKYKGRVSLTQAFAQSLNTVAVR
CCCCHHEEECCCCCCCCCHHCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHCCCEEEEE
VSETAGRGAVVKVAHRLGVIGSLSPLPSIALGVFEVSPLDLTAAYAPFANGGYAVVPHGI
EECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHEECCCCCHHHHHCCCCCCCEEEECCCE
LSIADRDGGLLYERQDSGPRRVVAPELARSMDTMLGAVVSWGTGRAAGLPDRTARGKTGT
EEEECCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SQGYRDAWFVGYAGKTLAGVWVGNDDGTPMRDVTGGILPTQIWHAFMLNAP
CCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ARRPQTDRMAPVFEASAPSRPPLIAERVVPELSDDAPRRAAPSPRPPPRRRKPGRSPAR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
KAPRRPRRRWVWPLIRLMLVGVIWMVIGLAGVVVWFGHDLPDPVTSANVTRRPSVTLLAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEC
DGSQLASFGDIQGDTVRTSDVPRALVLAILATEDRRFFKHFGLDLVGIARASVVNLRAGR
CCCHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCC
VVQGGSTLTQQVAKNLFLTHDRTFKRKIQEVLLALWLEQTFTKDQILSLYLNRVYLGAGT
EEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCC
HGVDAAARRYFDQPVGQINLYQAALLAGLPKAPSRLNPVTNPDGSRVRTLQVLQNMVEAK
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
MITPALAKQAAALADGAIPGARRGGMGSYFADWILERVDDFAGPRDRDLIVRTTLDPVQQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
RSAEAAVAGLLAEKGAAMKASQAALVALAPDGAVTAMVGGRDHATSPFNRAAQARRQPGS
HHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHCCCCC
AFKPFVFLAGLEAGLTPSTMMDDAPITVNGWSPGNYKDKYKGRVSLTQAFAQSLNTVAVR
CCCCHHEEECCCCCCCCCHHCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHCCCEEEEE
VSETAGRGAVVKVAHRLGVIGSLSPLPSIALGVFEVSPLDLTAAYAPFANGGYAVVPHGI
EECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHEECCCCCHHHHHCCCCCCCEEEECCCE
LSIADRDGGLLYERQDSGPRRVVAPELARSMDTMLGAVVSWGTGRAAGLPDRTARGKTGT
EEEECCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SQGYRDAWFVGYAGKTLAGVWVGNDDGTPMRDVTGGILPTQIWHAFMLNAP
CCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]