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The map label for this gene is mcpE [H]

Identifier: 83594571

GI number: 83594571

Start: 3736556

End: 3737893

Strand: Direct

Name: mcpE [H]

Synonym: Rru_A3241

Alternate gene names: 83594571

Gene position: 3736556-3737893 (Clockwise)

Preceding gene: 83594567

Following gene: 83594581

Centisome position: 85.84

GC content: 66.97

Gene sequence:

>1338_bases
GTGATCGATATTGAGTTCCATAAGGAAGAGCGGATCGATGCTCTGGGCCTTAACGCCGAAGCCCGCTCGCTGCTTCGTGA
AATTCAGCCCCTGGCCGCCGCCTGCATCGACCGGGCCCTTGATGGCGCCTATGACCGCATGCAGCGCTATCCCGACTCGC
GCCGCGCCTTTGACGGGGTGGACATCGCCCAAGCCAAGCGGGTGCAGCGTCAGCATTGGCTTGAAGACGTGCTGTCGCCC
GAGCCCACCGACTCCCAATTCGCCAATGCCATCTTATTGGCCCAAGGACGCCAGAAATCGGGGTTGGCCCTGCGCTGGTA
CTTCGTGTTCTTCATGGCGATCCTCGATGGCCTGATCGAGGGGATCACCCCGGCTTATCGCCGCAAACCCGAGCGGCTGA
GCAAGGCGATCTCGGTGCTGACGCGGGCGGTCTTCTTCGATCTCGACCTGTTCACCGCCGTTTACGTGGCGGCGGCGGAA
GGGGCGGCGGCAAGCGAACTCAACCGACAGGCCGACGCCTTCGAGGCGCAGGTTTCCGATATGGTCAAGGCGGTCGCCGC
CTCGATCGCCGAGGTTCAAGACACGGCCAGAACGATGACCGCCGTCGCCGACCAGACCCAAGCCCAGGCGCTCACCGCCC
TGACGGCCGGCGACGAGGCCGGGGCCAATGCCCAGACCGTGGCCGCCGCCACCGAGCAACTCAGCGCCTCGATCATCGAG
ATCGGCCGTCAGGTCGGCCAGTCGACGCGGATTTCGGGCGAGGCGGTGACGGCGGCGCGCGATACCGACCACTTGGTTCA
GGGACTGGCCGAGGTGGCGCGAAAGATCGGCGACGTGGTCAAGCTGATCAATTCGATCGCCAGCCAAACCAACCTTCTGG
CGCTGAACGCCACCATCGAGGCGGCGCGGGCCGGCGAGGCCGGGCGCGGCTTCGCCGTGGTCGCCGGCGAAGTCAAGAAC
CTCGCAAATCAGACGGCGAAGGCCACCGAGGAAATCTCGGGCCAGATCGCCGCCGTGCAGAAGGCCACCCAGGGCGCGGT
CGGCGCCATTCGCGGCATCGGCGCCACCATCACCGAGGTCAGTGCGATCACCGCGGCGATCGCCGCCGCCGTCGATCAGC
AGCGCGCCGCCACCGAGGAAATCGCCCGCAGCGTGCAACAGGTGGCGCAGAGCAGCGCCCTCGCCACCAAGGGAATGACC
ACGGTGACCCAGGCGGCCGAAGAGACCGGCGGCGCGGCGCGCCAGCTTCGTGACGGCCTCGACGGCCTGGGTCACAAATC
GGCGCGCCTAACCACCCAGGTCGATGATTTCCTGGGGCGAATCCGCCAGCGCGGTTAG

Upstream 100 bases:

>100_bases
CGGCGCTTAGCGGTGGTACCTCGGTTTGCAAACAAGCTTTAATTCCCCAAACTCCGGGGTCCGTTGGCCAATGACGCAAG
CAAAATGAGGAACGTGTACT

Downstream 100 bases:

>100_bases
CGACTCAGCGTCGCGCTCCGGGTCGGAGCGCTCGGGATTTGTTCTAATCCTCAAAGGAGCTCATCGCCTTGAGAAGGGCG
ATGAAGCTTTGGCGCATCCC

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MIDIEFHKEERIDALGLNAEARSLLREIQPLAAACIDRALDGAYDRMQRYPDSRRAFDGVDIAQAKRVQRQHWLEDVLSP
EPTDSQFANAILLAQGRQKSGLALRWYFVFFMAILDGLIEGITPAYRRKPERLSKAISVLTRAVFFDLDLFTAVYVAAAE
GAAASELNRQADAFEAQVSDMVKAVAASIAEVQDTARTMTAVADQTQAQALTALTAGDEAGANAQTVAAATEQLSASIIE
IGRQVGQSTRISGEAVTAARDTDHLVQGLAEVARKIGDVVKLINSIASQTNLLALNATIEAARAGEAGRGFAVVAGEVKN
LANQTAKATEEISGQIAAVQKATQGAVGAIRGIGATITEVSAITAAIAAAVDQQRAATEEIARSVQQVAQSSALATKGMT
TVTQAAEETGGAARQLRDGLDGLGHKSARLTTQVDDFLGRIRQRG

Sequences:

>Translated_445_residues
MIDIEFHKEERIDALGLNAEARSLLREIQPLAAACIDRALDGAYDRMQRYPDSRRAFDGVDIAQAKRVQRQHWLEDVLSP
EPTDSQFANAILLAQGRQKSGLALRWYFVFFMAILDGLIEGITPAYRRKPERLSKAISVLTRAVFFDLDLFTAVYVAAAE
GAAASELNRQADAFEAQVSDMVKAVAASIAEVQDTARTMTAVADQTQAQALTALTAGDEAGANAQTVAAATEQLSASIIE
IGRQVGQSTRISGEAVTAARDTDHLVQGLAEVARKIGDVVKLINSIASQTNLLALNATIEAARAGEAGRGFAVVAGEVKN
LANQTAKATEEISGQIAAVQKATQGAVGAIRGIGATITEVSAITAAIAAAVDQQRAATEEIARSVQQVAQSSALATKGMT
TVTQAAEETGGAARQLRDGLDGLGHKSARLTTQVDDFLGRIRQRG
>Mature_445_residues
MIDIEFHKEERIDALGLNAEARSLLREIQPLAAACIDRALDGAYDRMQRYPDSRRAFDGVDIAQAKRVQRQHWLEDVLSP
EPTDSQFANAILLAQGRQKSGLALRWYFVFFMAILDGLIEGITPAYRRKPERLSKAISVLTRAVFFDLDLFTAVYVAAAE
GAAASELNRQADAFEAQVSDMVKAVAASIAEVQDTARTMTAVADQTQAQALTALTAGDEAGANAQTVAAATEQLSASIIE
IGRQVGQSTRISGEAVTAARDTDHLVQGLAEVARKIGDVVKLINSIASQTNLLALNATIEAARAGEAGRGFAVVAGEVKN
LANQTAKATEEISGQIAAVQKATQGAVGAIRGIGATITEVSAITAAIAAAVDQQRAATEEIARSVQQVAQSSALATKGMT
TVTQAAEETGGAARQLRDGLDGLGHKSARLTTQVDDFLGRIRQRG

Specific function: Mediates Taxis Toward Dipeptides VIa An Interaction With The Periplasmic Dipeptide-Binding Protein. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Transduce A Signal From The Outsid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=231, Percent_Identity=38.0952380952381, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787690, Length=231, Percent_Identity=35.0649350649351, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788195, Length=208, Percent_Identity=37.9807692307692, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI2367378, Length=195, Percent_Identity=35.8974358974359, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789453, Length=203, Percent_Identity=33.0049261083744, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR012292
- InterPro:   IPR009050 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 47053; Mature: 47053

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIEFHKEERIDALGLNAEARSLLREIQPLAAACIDRALDGAYDRMQRYPDSRRAFDGV
CCCCCCCHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
DIAQAKRVQRQHWLEDVLSPEPTDSQFANAILLAQGRQKSGLALRWYFVFFMAILDGLIE
CHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
GITPAYRRKPERLSKAISVLTRAVFFDLDLFTAVYVAAAEGAAASELNRQADAFEAQVSD
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
MVKAVAASIAEVQDTARTMTAVADQTQAQALTALTAGDEAGANAQTVAAATEQLSASIIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IGRQVGQSTRISGEAVTAARDTDHLVQGLAEVARKIGDVVKLINSIASQTNLLALNATIE
HHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHH
AARAGEAGRGFAVVAGEVKNLANQTAKATEEISGQIAAVQKATQGAVGAIRGIGATITEV
HHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH
SAITAAIAAAVDQQRAATEEIARSVQQVAQSSALATKGMTTVTQAAEETGGAARQLRDGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
DGLGHKSARLTTQVDDFLGRIRQRG
HCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDIEFHKEERIDALGLNAEARSLLREIQPLAAACIDRALDGAYDRMQRYPDSRRAFDGV
CCCCCCCHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
DIAQAKRVQRQHWLEDVLSPEPTDSQFANAILLAQGRQKSGLALRWYFVFFMAILDGLIE
CHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
GITPAYRRKPERLSKAISVLTRAVFFDLDLFTAVYVAAAEGAAASELNRQADAFEAQVSD
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
MVKAVAASIAEVQDTARTMTAVADQTQAQALTALTAGDEAGANAQTVAAATEQLSASIIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IGRQVGQSTRISGEAVTAARDTDHLVQGLAEVARKIGDVVKLINSIASQTNLLALNATIE
HHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHH
AARAGEAGRGFAVVAGEVKNLANQTAKATEEISGQIAAVQKATQGAVGAIRGIGATITEV
HHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH
SAITAAIAAAVDQQRAATEEIARSVQQVAQSSALATKGMTTVTQAAEETGGAARQLRDGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
DGLGHKSARLTTQVDDFLGRIRQRG
HCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]