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The map label for this gene is thrB

Identifier: 83594383

GI number: 83594383

Start: 3516320

End: 3517285

Strand: Direct

Name: thrB

Synonym: Rru_A3053

Alternate gene names: 83594383

Gene position: 3516320-3517285 (Clockwise)

Preceding gene: 83594377

Following gene: 83594384

Centisome position: 80.78

GC content: 64.8

Gene sequence:

>966_bases
ATGGCCGTCTATACCGATGTTTCCGATGATGATCTAACCACCTTCCTGGAAGGCTATGACATCGGCCGCCTGCGCGCCTG
CAAGGGGATCGCCGAAGGGGTGGAGAATTCCAACTTCCTGCTGGTCACCGACCGCGGCCCCCATATCCTGACGCTCTATG
AAAAGCGGGTGAACCCCGACGATCTGCCGTTCTTCCTGGGGCTTTTGCGCCATCTGGCGGCGCGCGACATTCCCTGCCCG
CAGCCGGTCGCCGGCCGCGACGGCGCCGTGCTTCACACCCTGTGCGACCGCCCGGCGGCCATCGTCACCTTTCTCGATGG
CGTCTGGCCCAAGCGCCCCGAGGTCCGCCATTGCGCCCAGCTTGGCGAGGCCCTGGCCCGGCTGCATCTGGCGGGCGGCG
ATTACGCGCCGACCCGGCGCAACAGCCTGTCGGTCGATGGCTGGCGGCCGTTGTTCGATGCCGCCGCCGAACGCGCCGAC
AGCGTCAAACCCGGGTTGCGCGCCGAACTGGAAACCGAACTCGACGCCCTGGAGGCCCTGTGGCCCCACGACCTGCCCAC
TGGCATCATCCATGCCGATCTGTTCCCCGATAACGTCTTCTTCGTTGACGACACCCTGTCGGGGCTGATCGATTTCTATT
TCGCCTGCGACGATTTCCTGGCCTATGACCTTGCCGTCTGCCTCAACGCTTGGTGCTTCGAGGGCGAGCGGGAATTCAAC
GTCACCAAGGCCCGTCACATGCTAACCCGCTATGAAAAGGTCCGGCCCTTGAGCGATGCCGAATTCGCCGCCCTGCCGCT
GTTGGCGCGCGGCGCGGCGATGCGCTTCTTGCTCACCCGGCTCTATGATTGGCTGAACACCCCGCCGGGCGCCATGGTCC
GGCCAAAGGATCCGATGGAATATTATCACAAGCTGGCCTTCCACCGCGCCGTCTCCGGCCCGGGCGCCTATGGATTGAGC
CGATGA

Upstream 100 bases:

>100_bases
CGCCCGCCAAGGGCGCGGGTCTTCGCGCGGTTCGGCTTTTCAAGGGGCTTACAAAGCTGTTAGATGGCGCGCCCTCCCCG
CCCGAACCGGATTGTTGCCG

Downstream 100 bases:

>100_bases
GCGCGGCGGCCGGCGACGAGATCAAGCGCGTGCGCGTCGATATGTTCACCGATGGCGCCTGTTCGGGCAATCCGGGCCCG
GGCGGCTGGGGCACCATCTT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAVYTDVSDDDLTTFLEGYDIGRLRACKGIAEGVENSNFLLVTDRGPHILTLYEKRVNPDDLPFFLGLLRHLAARDIPCP
QPVAGRDGAVLHTLCDRPAAIVTFLDGVWPKRPEVRHCAQLGEALARLHLAGGDYAPTRRNSLSVDGWRPLFDAAAERAD
SVKPGLRAELETELDALEALWPHDLPTGIIHADLFPDNVFFVDDTLSGLIDFYFACDDFLAYDLAVCLNAWCFEGEREFN
VTKARHMLTRYEKVRPLSDAEFAALPLLARGAAMRFLLTRLYDWLNTPPGAMVRPKDPMEYYHKLAFHRAVSGPGAYGLS
R

Sequences:

>Translated_321_residues
MAVYTDVSDDDLTTFLEGYDIGRLRACKGIAEGVENSNFLLVTDRGPHILTLYEKRVNPDDLPFFLGLLRHLAARDIPCP
QPVAGRDGAVLHTLCDRPAAIVTFLDGVWPKRPEVRHCAQLGEALARLHLAGGDYAPTRRNSLSVDGWRPLFDAAAERAD
SVKPGLRAELETELDALEALWPHDLPTGIIHADLFPDNVFFVDDTLSGLIDFYFACDDFLAYDLAVCLNAWCFEGEREFN
VTKARHMLTRYEKVRPLSDAEFAALPLLARGAAMRFLLTRLYDWLNTPPGAMVRPKDPMEYYHKLAFHRAVSGPGAYGLS
R
>Mature_320_residues
AVYTDVSDDDLTTFLEGYDIGRLRACKGIAEGVENSNFLLVTDRGPHILTLYEKRVNPDDLPFFLGLLRHLAARDIPCPQ
PVAGRDGAVLHTLCDRPAAIVTFLDGVWPKRPEVRHCAQLGEALARLHLAGGDYAPTRRNSLSVDGWRPLFDAAAERADS
VKPGLRAELETELDALEALWPHDLPTGIIHADLFPDNVFFVDDTLSGLIDFYFACDDFLAYDLAVCLNAWCFEGEREFNV
TKARHMLTRYEKVRPLSDAEFAALPLLARGAAMRFLLTRLYDWLNTPPGAMVRPKDPMEYYHKLAFHRAVSGPGAYGLSR

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_RHORT (Q2RPU7)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428135.1
- ProteinModelPortal:   Q2RPU7
- SMR:   Q2RPU7
- STRING:   Q2RPU7
- GeneID:   3836499
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3053
- NMPDR:   fig|1085.1.peg.694
- eggNOG:   COG2334
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- BioCyc:   RRUB269796:RRU_A3053-MONOMER
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 35873; Mature: 35742

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDVSDDDLTTFLEGYDIGRLRACKGIAEGVENSNFLLVTDRGPHILTLYEKRVNPD
CEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCC
DLPFFLGLLRHLAARDIPCPQPVAGRDGAVLHTLCDRPAAIVTFLDGVWPKRPEVRHCAQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHH
LGEALARLHLAGGDYAPTRRNSLSVDGWRPLFDAAAERADSVKPGLRAELETELDALEAL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WPHDLPTGIIHADLFPDNVFFVDDTLSGLIDFYFACDDFLAYDLAVCLNAWCFEGEREFN
CCCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VTKARHMLTRYEKVRPLSDAEFAALPLLARGAAMRFLLTRLYDWLNTPPGAMVRPKDPME
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YYHKLAFHRAVSGPGAYGLSR
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVYTDVSDDDLTTFLEGYDIGRLRACKGIAEGVENSNFLLVTDRGPHILTLYEKRVNPD
EEECCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCC
DLPFFLGLLRHLAARDIPCPQPVAGRDGAVLHTLCDRPAAIVTFLDGVWPKRPEVRHCAQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHH
LGEALARLHLAGGDYAPTRRNSLSVDGWRPLFDAAAERADSVKPGLRAELETELDALEAL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WPHDLPTGIIHADLFPDNVFFVDDTLSGLIDFYFACDDFLAYDLAVCLNAWCFEGEREFN
CCCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VTKARHMLTRYEKVRPLSDAEFAALPLLARGAAMRFLLTRLYDWLNTPPGAMVRPKDPME
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YYHKLAFHRAVSGPGAYGLSR
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA