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The map label for this gene is ackA [H]

Identifier: 83594328

GI number: 83594328

Start: 3452134

End: 3453351

Strand: Reverse

Name: ackA [H]

Synonym: Rru_A2998

Alternate gene names: 83594328

Gene position: 3453351-3452134 (Counterclockwise)

Preceding gene: 83594329

Following gene: 83594327

Centisome position: 79.34

GC content: 68.14

Gene sequence:

>1218_bases
ATGATCCATGAGAACTCTCTGATCCTTGTGCTCAACTCCGGCAGTTCATCGCTGAAGTTCGCCCTTTTCGCCGCCGACGC
CCGCGAGCCGTTGTGTTCGGGTCTGGCCGAATGCCTGGGCCGCGCCGATGCCCGCCTGACCGTCAAGCGCGACGGCACCA
AGGCGGTGACGCCGATGGAAGGCGGCGGCCACGACGTCGCCCTCGGCGCCATCCTCGATATCCTGGCCTCGGCCGATCTG
TTGGCGCCGATCCGCGCCGTCGGTCACCGGGTGACCCATGGCGGCGAGCGCTTCCGCGCCTCGGCCCTGATCACCGACGC
CGCCCTGGCCGATATCGAAGCCTGCAGCGCGCTCGCCCCCTTGCATAATCCGCCCAATCTGTTGGGCATCCGCATGGCCC
GGGCCCGCATGCCCGATGTGCCCCATGTCGCCGTCTTCGATACCTCGTTCCACCAGACCATGCCGCGCGCCGCCTTCATG
TACGCCCTGCCGCTGCGCTTCTATGCGAAGTTCGGCGTGCGCCGTTACGGCTTCCACGGCACCAGCCACCGCTTCGTCGC
CGCCCAGGCGGTGACGCTGCTCGGCCTTGATCCCGAGGATCACGGTCTGGTCATCGCGCATCTCGGCAATGGCTCCTCGG
CCACCGCCGTGCTCGATGGCCGCAGCGTCGACACCACCATGGGCATGACGCCGCTTGAAGGCCTAGTGATGGGCACGCGG
TCGGGCGATGTCGATGCCGGGGCGCTCAGCCATATCGCCCGCCAGACCGGTTGGAGCCGCGAAGAGCTTGATGCGGTTCT
GAACAAGGAAAGCGGCCTGCTGGGTCTGTCGGGTCTGTCCAACGATTGCCGCACCCTGGAAGCCGCCGCCGAGGACGGCA
ACGACGGCGCCCGTCTCGCCCTTGATGTGTTCGTGCACCGGCTGGCCCGCCATATCGGCGGTCTGGCGATGGCCCTGCCG
CGTCTTGACGCCGTGGTCTTTACCGGGGGCATCGGCGAAAACTCGTCGCGGCTGCGCGCCGCCACCCTCGAGCGCCTGAA
GCCGCTCGGCCTGACCCTGGACGCCGCGGCCAACGAGCGCTGCGTGCGCGGCGTCTCGGGCCGCATCAGCCAGGGGCTTT
TTCCCGCCGCCGCGGTCATTCCGACCGACGAGGAATGGATGATCGCCCAGGACACCCTGGATCTGACCTCCGACGAGTCC
TTGTCCTGCGTCGCCTAA

Upstream 100 bases:

>100_bases
CAGGTCGACGCCGCCCGCGCCCGCTTCGCCGAGCGCGGCTTGAAGGTGTTTTGAAACACCCACCGCGGTCCGTGCCGCTA
GCCCCTTTGGGACCACCGAC

Downstream 100 bases:

>100_bases
AGCAAATCCCGAGCGATCTGAACCAGATCGCGACGACGATTTGCTTGACTATCAGCCTGTTAGAGCGGTGCGCCGGGACT
TTAGGTGTTACATATGCCGC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MIHENSLILVLNSGSSSLKFALFAADAREPLCSGLAECLGRADARLTVKRDGTKAVTPMEGGGHDVALGAILDILASADL
LAPIRAVGHRVTHGGERFRASALITDAALADIEACSALAPLHNPPNLLGIRMARARMPDVPHVAVFDTSFHQTMPRAAFM
YALPLRFYAKFGVRRYGFHGTSHRFVAAQAVTLLGLDPEDHGLVIAHLGNGSSATAVLDGRSVDTTMGMTPLEGLVMGTR
SGDVDAGALSHIARQTGWSREELDAVLNKESGLLGLSGLSNDCRTLEAAAEDGNDGARLALDVFVHRLARHIGGLAMALP
RLDAVVFTGGIGENSSRLRAATLERLKPLGLTLDAAANERCVRGVSGRISQGLFPAAAVIPTDEEWMIAQDTLDLTSDES
LSCVA

Sequences:

>Translated_405_residues
MIHENSLILVLNSGSSSLKFALFAADAREPLCSGLAECLGRADARLTVKRDGTKAVTPMEGGGHDVALGAILDILASADL
LAPIRAVGHRVTHGGERFRASALITDAALADIEACSALAPLHNPPNLLGIRMARARMPDVPHVAVFDTSFHQTMPRAAFM
YALPLRFYAKFGVRRYGFHGTSHRFVAAQAVTLLGLDPEDHGLVIAHLGNGSSATAVLDGRSVDTTMGMTPLEGLVMGTR
SGDVDAGALSHIARQTGWSREELDAVLNKESGLLGLSGLSNDCRTLEAAAEDGNDGARLALDVFVHRLARHIGGLAMALP
RLDAVVFTGGIGENSSRLRAATLERLKPLGLTLDAAANERCVRGVSGRISQGLFPAAAVIPTDEEWMIAQDTLDLTSDES
LSCVA
>Mature_405_residues
MIHENSLILVLNSGSSSLKFALFAADAREPLCSGLAECLGRADARLTVKRDGTKAVTPMEGGGHDVALGAILDILASADL
LAPIRAVGHRVTHGGERFRASALITDAALADIEACSALAPLHNPPNLLGIRMARARMPDVPHVAVFDTSFHQTMPRAAFM
YALPLRFYAKFGVRRYGFHGTSHRFVAAQAVTLLGLDPEDHGLVIAHLGNGSSATAVLDGRSVDTTMGMTPLEGLVMGTR
SGDVDAGALSHIARQTGWSREELDAVLNKESGLLGLSGLSNDCRTLEAAAEDGNDGARLALDVFVHRLARHIGGLAMALP
RLDAVVFTGGIGENSSRLRAATLERLKPLGLTLDAAANERCVRGVSGRISQGLFPAAAVIPTDEEWMIAQDTLDLTSDES
LSCVA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=51.5151515151515, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1788633, Length=399, Percent_Identity=46.1152882205514, Blast_Score=337, Evalue=6e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 42648; Mature: 42648

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHENSLILVLNSGSSSLKFALFAADAREPLCSGLAECLGRADARLTVKRDGTKAVTPME
CCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCEEECCCC
GGGHDVALGAILDILASADLLAPIRAVGHRVTHGGERFRASALITDAALADIEACSALAP
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LHNPPNLLGIRMARARMPDVPHVAVFDTSFHQTMPRAAFMYALPLRFYAKFGVRRYGFHG
CCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHCCHHCCCCC
TSHRFVAAQAVTLLGLDPEDHGLVIAHLGNGSSATAVLDGRSVDTTMGMTPLEGLVMGTR
CCCEEEHEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEECC
SGDVDAGALSHIARQTGWSREELDAVLNKESGLLGLSGLSNDCRTLEAAAEDGNDGARLA
CCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHH
LDVFVHRLARHIGGLAMALPRLDAVVFTGGIGENSSRLRAATLERLKPLGLTLDAAANER
HHHHHHHHHHHHCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCHH
CVRGVSGRISQGLFPAAAVIPTDEEWMIAQDTLDLTSDESLSCVA
HHHCCCCHHHCCCCCCEEECCCCCCEEEEECCCCCCCCCCCEECC
>Mature Secondary Structure
MIHENSLILVLNSGSSSLKFALFAADAREPLCSGLAECLGRADARLTVKRDGTKAVTPME
CCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCEEECCCC
GGGHDVALGAILDILASADLLAPIRAVGHRVTHGGERFRASALITDAALADIEACSALAP
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LHNPPNLLGIRMARARMPDVPHVAVFDTSFHQTMPRAAFMYALPLRFYAKFGVRRYGFHG
CCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHCCHHCCCCC
TSHRFVAAQAVTLLGLDPEDHGLVIAHLGNGSSATAVLDGRSVDTTMGMTPLEGLVMGTR
CCCEEEHEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEECC
SGDVDAGALSHIARQTGWSREELDAVLNKESGLLGLSGLSNDCRTLEAAAEDGNDGARLA
CCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHH
LDVFVHRLARHIGGLAMALPRLDAVVFTGGIGENSSRLRAATLERLKPLGLTLDAAANER
HHHHHHHHHHHHCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCHH
CVRGVSGRISQGLFPAAAVIPTDEEWMIAQDTLDLTSDESLSCVA
HHHCCCCHHHCCCCCCEEECCCCCCEEEEECCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]