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The map label for this gene is moaE [H]

Identifier: 83594147

GI number: 83594147

Start: 3247292

End: 3247780

Strand: Direct

Name: moaE [H]

Synonym: Rru_A2815

Alternate gene names: 83594147

Gene position: 3247292-3247780 (Clockwise)

Preceding gene: 83594146

Following gene: 83594148

Centisome position: 74.6

GC content: 71.17

Gene sequence:

>489_bases
ATGGCCGTTCACGTCCAAAGCGCCGATTTCGACAGCGCCGCCGAGATCGCCCGCTTCGAGCGCCAAGCCGCCCTCAAGGG
CGCCGGGGCGGTGGCCAGCTTCTGCGGGCTGGTGCGCGGCCGCGAGGGGGAGGATGGTCCGCTGATCGGGGCGATGACCC
TGGAACACTACCCCGGCATGACCGAGCGCGCCCTGGCCGCCATCGAGGCCGAGGCGCTGGCCCGCTGGCCGCTGACCGAT
AGCCTGATCATCCACCGCTTCGGCCGGCTGGAGCCGGGCGCGCGCATCGTGCTGGTCTGCACCGCGTCCTCGCACCGCGA
AGCCGCCTTCGCCGCCTGCGCCTTTCTGATGGACTGGCTCAAGACCAAGGCGCCCTTCTGGAAAAAAGAGGAAACCGCCG
AGGGACCGCGGTGGGTCGACGCCAAGGCCGAAGACGACGCCCGCGCCGCGGCCTGGAACGAGGCAAGCGCGCCGCGCAAC
CCCGACTAA

Upstream 100 bases:

>100_bases
CTGCGCGCCGCGGTCAATCAAGACCTCGCCACCCCCGAGACGCCTTTGACCGCCAGCGATGAAGTGGCGTTCTTCCCGCC
GCTGACCGGGGGCTGAGGCG

Downstream 100 bases:

>100_bases
GCCGCGACCATTTTGCCGACGAAACAAGACAGATGCAAAAGGCTCTAGTCATAGCGGAAGGGATGTATTAGCTTTAAGAC
TGTAGACCGCCCAAGGTACG

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MAVHVQSADFDSAAEIARFERQAALKGAGAVASFCGLVRGREGEDGPLIGAMTLEHYPGMTERALAAIEAEALARWPLTD
SLIIHRFGRLEPGARIVLVCTASSHREAAFAACAFLMDWLKTKAPFWKKEETAEGPRWVDAKAEDDARAAAWNEASAPRN
PD

Sequences:

>Translated_162_residues
MAVHVQSADFDSAAEIARFERQAALKGAGAVASFCGLVRGREGEDGPLIGAMTLEHYPGMTERALAAIEAEALARWPLTD
SLIIHRFGRLEPGARIVLVCTASSHREAAFAACAFLMDWLKTKAPFWKKEETAEGPRWVDAKAEDDARAAAWNEASAPRN
PD
>Mature_161_residues
AVHVQSADFDSAAEIARFERQAALKGAGAVASFCGLVRGREGEDGPLIGAMTLEHYPGMTERALAAIEAEALARWPLTDS
LIIHRFGRLEPGARIVLVCTASSHREAAFAACAFLMDWLKTKAPFWKKEETAEGPRWVDAKAEDDARAAAWNEASAPRNP
D

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=110, Percent_Identity=29.0909090909091, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1787003, Length=124, Percent_Identity=54.0322580645161, Blast_Score=133, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17550; Mature: 17419

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHVQSADFDSAAEIARFERQAALKGAGAVASFCGLVRGREGEDGPLIGAMTLEHYPGM
CEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEHHHCCCH
TERALAAIEAEALARWPLTDSLIIHRFGRLEPGARIVLVCTASSHREAAFAACAFLMDWL
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
KTKAPFWKKEETAEGPRWVDAKAEDDARAAAWNEASAPRNPD
HHCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AVHVQSADFDSAAEIARFERQAALKGAGAVASFCGLVRGREGEDGPLIGAMTLEHYPGM
EEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEHHHCCCH
TERALAAIEAEALARWPLTDSLIIHRFGRLEPGARIVLVCTASSHREAAFAACAFLMDWL
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
KTKAPFWKKEETAEGPRWVDAKAEDDARAAAWNEASAPRNPD
HHCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]