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The map label for this gene is dcd

Identifier: 83594126

GI number: 83594126

Start: 3228568

End: 3229155

Strand: Direct

Name: dcd

Synonym: Rru_A2794

Alternate gene names: 83594126

Gene position: 3228568-3229155 (Clockwise)

Preceding gene: 83594125

Following gene: 83594132

Centisome position: 74.17

GC content: 65.31

Gene sequence:

>588_bases
ATGAAACTGTCCGACACCGATATCCGGCGCTATATGGCCGAGGGACGTATCGCCATTGATCCGGTTCCCGGAGAAGACGC
GATCGGGGCGATGTCGGTTGATCTGCAGTTGGGGGATTCGTTCCGGGTTTTCGTTCCGGGCAAGGTCAGCCATGTCGATT
TGGCGCCGCCCGGCGGCATCAAGGGCCGCGATATCGAAGCCCTGATGGGCCATGTCGAAGTCGGCGAGAACGAGGCGTTC
TATCTGCATCCGGGCGAATTCGCCCTCGGCATCACCATCCAGCGCGTGCGCCTGCCCGCCGATGTCGCCGGCCGCCTGGA
TGGCCGCAGCAGCCTCGCCCGCCTGGGGCTGATGGTCCATGCCACCGCCCATACCATCGATCCCGGCTGGGACGGCCGCA
TCACCCTGGAGTTCTTCAACTGCGGCCCGCTGCCGCTGGCCATGCGCCCGGGCATGCGGATCTGCGCCATCAGCTTCGAA
GCCCTGATGTCGCCGACCTCCAAGCCCTATGCCGCCAGCCCGACCGCCAAATACAAGGACCAACTCGCCCCCCTGCCCAG
CCGACTGGCCAGCGACCAATCGGCATAA

Upstream 100 bases:

>100_bases
AGTGACGGGGAATCGGCGCAACCGGTGGACCTTTCGCCCAATTCATGGAATCTTCGCCGCCATTCTTCACGCTTTTTGTC
GCCCCCGGAGCACCCGCCCC

Downstream 100 bases:

>100_bases
GGGCGGCGAGACAGCATCGCTCTAACGGATGGCGGCGCTCACCAAGCTGGCGACGCCGCGTTCCAGGCTGGATTTGAGCA
CCGCGCCGAACACCGCCCGC

Product: dCTP deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKLSDTDIRRYMAEGRIAIDPVPGEDAIGAMSVDLQLGDSFRVFVPGKVSHVDLAPPGGIKGRDIEALMGHVEVGENEAF
YLHPGEFALGITIQRVRLPADVAGRLDGRSSLARLGLMVHATAHTIDPGWDGRITLEFFNCGPLPLAMRPGMRICAISFE
ALMSPTSKPYAASPTAKYKDQLAPLPSRLASDQSA

Sequences:

>Translated_195_residues
MKLSDTDIRRYMAEGRIAIDPVPGEDAIGAMSVDLQLGDSFRVFVPGKVSHVDLAPPGGIKGRDIEALMGHVEVGENEAF
YLHPGEFALGITIQRVRLPADVAGRLDGRSSLARLGLMVHATAHTIDPGWDGRITLEFFNCGPLPLAMRPGMRICAISFE
ALMSPTSKPYAASPTAKYKDQLAPLPSRLASDQSA
>Mature_195_residues
MKLSDTDIRRYMAEGRIAIDPVPGEDAIGAMSVDLQLGDSFRVFVPGKVSHVDLAPPGGIKGRDIEALMGHVEVGENEAF
YLHPGEFALGITIQRVRLPADVAGRLDGRSSLARLGLMVHATAHTIDPGWDGRITLEFFNCGPLPLAMRPGMRICAISFE
ALMSPTSKPYAASPTAKYKDQLAPLPSRLASDQSA

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=193, Percent_Identity=49.740932642487, Blast_Score=190, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_RHORT (Q2RQK4)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_427878.1
- ProteinModelPortal:   Q2RQK4
- SMR:   Q2RQK4
- STRING:   Q2RQK4
- GeneID:   3836234
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2794
- NMPDR:   fig|1085.1.peg.440
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   FSGHVTL
- PhylomeDB:   Q2RQK4
- BioCyc:   RRUB269796:RRU_A2794-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20938; Mature: 20938

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSDTDIRRYMAEGRIAIDPVPGEDAIGAMSVDLQLGDSFRVFVPGKVSHVDLAPPGGI
CCCCHHHHHHHHHCCCEEECCCCCCCCCEEEEEEEEECCCEEEEECCCEEEEECCCCCCC
KGRDIEALMGHVEVGENEAFYLHPGEFALGITIQRVRLPADVAGRLDGRSSLARLGLMVH
CCCCHHHHCCEEEECCCCEEEEECCCEEEEEEEEEEECCHHHHHCCCCHHHHHHHCEEEE
ATAHTIDPGWDGRITLEFFNCGPLPLAMRPGMRICAISFEALMSPTSKPYAASPTAKYKD
EEEEECCCCCCCEEEEEEECCCCCCEEECCCCEEEEEEHHHHHCCCCCCCCCCCCHHHHH
QLAPLPSRLASDQSA
HCCCCHHHHCCCCCC
>Mature Secondary Structure
MKLSDTDIRRYMAEGRIAIDPVPGEDAIGAMSVDLQLGDSFRVFVPGKVSHVDLAPPGGI
CCCCHHHHHHHHHCCCEEECCCCCCCCCEEEEEEEEECCCEEEEECCCEEEEECCCCCCC
KGRDIEALMGHVEVGENEAFYLHPGEFALGITIQRVRLPADVAGRLDGRSSLARLGLMVH
CCCCHHHHCCEEEECCCCEEEEECCCEEEEEEEEEEECCHHHHHCCCCHHHHHHHCEEEE
ATAHTIDPGWDGRITLEFFNCGPLPLAMRPGMRICAISFEALMSPTSKPYAASPTAKYKD
EEEEECCCCCCCEEEEEEECCCCCCEEECCCCEEEEEEHHHHHCCCCCCCCCCCCHHHHH
QLAPLPSRLASDQSA
HCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA