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The map label for this gene is csd1 [H]

Identifier: 83593902

GI number: 83593902

Start: 2988697

End: 2989965

Strand: Reverse

Name: csd1 [H]

Synonym: Rru_A2570

Alternate gene names: 83593902

Gene position: 2989965-2988697 (Counterclockwise)

Preceding gene: 83593903

Following gene: 83593901

Centisome position: 68.69

GC content: 65.56

Gene sequence:

>1269_bases
ATGATGGCGAGCAGCACGGCGGCGCGCGAGCCGCACCCAGGCGACGACAGCCCTTATGACGTGGAGGCGATCCGCGCCGA
TTTTCCAATCTTCGGCACCCAGGTCCATGGGCAGCCGCTGATCTATCTCGATAGCGGCGCCTCGGCCCAGAAGCCGCGCG
CCGTGATCGATGCCATGCGTTTGATGTATGAGGGCGAATACGCCAACGTCCATCGCGGCGCCTATTGGCTGTCGGAGCGG
TCGACCACGCGCTACGAGGAAGCCCGCCAGACCGTGCGCGGCTTCATCAACGCCGCCCGGTCGGAGGAGGTGGTCTTCAC
CATGGGGGCGACCGACGCCATCAATCTGGTCGCCTATAGCTTCGGCCGGGGTCTGCTCCAGGCCGGCGATGAGATCATCA
TCAGCGCCCTTGAGCACCATTCCAACATCGTGCCCTGGCAGATCCTGCGCGACGAGCGCGGCATCGTGTTGAAGGTCTGC
CCGATCACCGATGCCGGCGACCTTGATCTTGGCGCCCTGGAAACGCTGCTTGGCCCGCGCACCAAGCTGGTGGCGATGGC
CCATACCTCGAATGTTCTGGGCACCATCTTGCCGGTCGAGACCATCATCAAGATGGCCCATGGCGTTGGCGCCCGGGTGC
TGCTTGACGGCTGTCAGGCCGTCGTTCACACCGCCGTCGACGTTCAGGCGCTCGATGTCGATTTCTATGCCTTTTCCGGC
CACAAGCTGTATGGCCCGACCGGCATCGGCGTGCTCTACGCCAAGCACGAGTTGCTCGAGGCCATGCCGCCCTTCCGCGG
CGGCGGCGACATGATCGCCAGCGTGAGCTTTGAGCACTCGGTCTGGGCCGAGCCGCCGGCCAAATTCGAGGCGGGAACGC
CGCCGATCGTCCAGGCGGTCGGGCTGGCCAGCGCCATCGACTATGTCTCGGCCATCGGCCTTGCGCGCATCGCCCGCCAC
GAGGCCGATCTGCTGAACTATGCCACCCAGAAGATGACGGTCCTTCCCGGGCTGACCATCCATGGCACCTCGACCCGCAA
GGCAGCGGTGATCTCGTTCACCATGGATTGCGCCCATCCCCACGATATGGCGACCCTGCTCGATCGCTCGGGCGTGTGCA
TCCGGGTCGGCCATCATTGCGCCCAGCCGCTGATGGCGCGTCTGGGCGTCAGCGCGACGGCGCGGGCCTCTTTCGCCCTG
TACAACACCCGCGCCGATGTCGACGCCTTCGTCAAGGCGCTGGAGAAGGTTCGCGCCTTCTTCGCCTGA

Upstream 100 bases:

>100_bases
GAAGTCGGCGATCTGCCGGTGCGCGCGGCGATGATCGCCAAGGTGCGCGATTGGCAGCGCGCCCGTGACGGCGCGGTGTG
GAGCGAGTAGGGGGAACGCG

Downstream 100 bases:

>100_bases
CCGGGCGCGTGGTTTGGTTTTCGTCTATCCGACCTTAGGAAAAGAGCCCTGACATGATGCCTCCCTATGCCATGCCGGCC
GCCATGATGGATCCCCCCGA

Product: cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MMASSTAAREPHPGDDSPYDVEAIRADFPIFGTQVHGQPLIYLDSGASAQKPRAVIDAMRLMYEGEYANVHRGAYWLSER
STTRYEEARQTVRGFINAARSEEVVFTMGATDAINLVAYSFGRGLLQAGDEIIISALEHHSNIVPWQILRDERGIVLKVC
PITDAGDLDLGALETLLGPRTKLVAMAHTSNVLGTILPVETIIKMAHGVGARVLLDGCQAVVHTAVDVQALDVDFYAFSG
HKLYGPTGIGVLYAKHELLEAMPPFRGGGDMIASVSFEHSVWAEPPAKFEAGTPPIVQAVGLASAIDYVSAIGLARIARH
EADLLNYATQKMTVLPGLTIHGTSTRKAAVISFTMDCAHPHDMATLLDRSGVCIRVGHHCAQPLMARLGVSATARASFAL
YNTRADVDAFVKALEKVRAFFA

Sequences:

>Translated_422_residues
MMASSTAAREPHPGDDSPYDVEAIRADFPIFGTQVHGQPLIYLDSGASAQKPRAVIDAMRLMYEGEYANVHRGAYWLSER
STTRYEEARQTVRGFINAARSEEVVFTMGATDAINLVAYSFGRGLLQAGDEIIISALEHHSNIVPWQILRDERGIVLKVC
PITDAGDLDLGALETLLGPRTKLVAMAHTSNVLGTILPVETIIKMAHGVGARVLLDGCQAVVHTAVDVQALDVDFYAFSG
HKLYGPTGIGVLYAKHELLEAMPPFRGGGDMIASVSFEHSVWAEPPAKFEAGTPPIVQAVGLASAIDYVSAIGLARIARH
EADLLNYATQKMTVLPGLTIHGTSTRKAAVISFTMDCAHPHDMATLLDRSGVCIRVGHHCAQPLMARLGVSATARASFAL
YNTRADVDAFVKALEKVRAFFA
>Mature_422_residues
MMASSTAAREPHPGDDSPYDVEAIRADFPIFGTQVHGQPLIYLDSGASAQKPRAVIDAMRLMYEGEYANVHRGAYWLSER
STTRYEEARQTVRGFINAARSEEVVFTMGATDAINLVAYSFGRGLLQAGDEIIISALEHHSNIVPWQILRDERGIVLKVC
PITDAGDLDLGALETLLGPRTKLVAMAHTSNVLGTILPVETIIKMAHGVGARVLLDGCQAVVHTAVDVQALDVDFYAFSG
HKLYGPTGIGVLYAKHELLEAMPPFRGGGDMIASVSFEHSVWAEPPAKFEAGTPPIVQAVGLASAIDYVSAIGLARIARH
EADLLNYATQKMTVLPGLTIHGTSTRKAAVISFTMDCAHPHDMATLLDRSGVCIRVGHHCAQPLMARLGVSATARASFAL
YNTRADVDAFVKALEKVRAFFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=229, Percent_Identity=28.3842794759825, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI156713448, Length=455, Percent_Identity=24.8351648351648, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1787970, Length=400, Percent_Identity=50.75, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1789175, Length=398, Percent_Identity=41.9597989949749, Blast_Score=318, Evalue=3e-88,
Organism=Escherichia coli, GI48994898, Length=268, Percent_Identity=28.7313432835821, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193211090, Length=349, Percent_Identity=28.3667621776504, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25143064, Length=218, Percent_Identity=27.9816513761468, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319831, Length=239, Percent_Identity=30.5439330543933, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129463, Length=280, Percent_Identity=29.2857142857143, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45476; Mature: 45476

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMASSTAAREPHPGDDSPYDVEAIRADFPIFGTQVHGQPLIYLDSGASAQKPRAVIDAMR
CCCCCCCCCCCCCCCCCCCCHHEEECCCCEECEEECCCEEEEEECCCCCCCCHHHHHHHH
LMYEGEYANVHRGAYWLSERSTTRYEEARQTVRGFINAARSEEVVFTMGATDAINLVAYS
HHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
FGRGLLQAGDEIIISALEHHSNIVPWQILRDERGIVLKVCPITDAGDLDLGALETLLGPR
HCCHHHHCCHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCC
TKLVAMAHTSNVLGTILPVETIIKMAHGVGARVLLDGCQAVVHTAVDVQALDVDFYAFSG
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEEEEEEEECC
HKLYGPTGIGVLYAKHELLEAMPPFRGGGDMIASVSFEHSVWAEPPAKFEAGTPPIVQAV
CEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
GLASAIDYVSAIGLARIARHEADLLNYATQKMTVLPGLTIHGTSTRKAAVISFTMDCAHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCEEEEEEEECCCCC
HDMATLLDRSGVCIRVGHHCAQPLMARLGVSATARASFALYNTRADVDAFVKALEKVRAF
HHHHHHHCCCCCEEEECHHHHHHHHHHHCCCHHHCEEEEEEECCCCHHHHHHHHHHHHHH
FA
CC
>Mature Secondary Structure
MMASSTAAREPHPGDDSPYDVEAIRADFPIFGTQVHGQPLIYLDSGASAQKPRAVIDAMR
CCCCCCCCCCCCCCCCCCCCHHEEECCCCEECEEECCCEEEEEECCCCCCCCHHHHHHHH
LMYEGEYANVHRGAYWLSERSTTRYEEARQTVRGFINAARSEEVVFTMGATDAINLVAYS
HHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
FGRGLLQAGDEIIISALEHHSNIVPWQILRDERGIVLKVCPITDAGDLDLGALETLLGPR
HCCHHHHCCHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCC
TKLVAMAHTSNVLGTILPVETIIKMAHGVGARVLLDGCQAVVHTAVDVQALDVDFYAFSG
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEEEEEEEECC
HKLYGPTGIGVLYAKHELLEAMPPFRGGGDMIASVSFEHSVWAEPPAKFEAGTPPIVQAV
CEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
GLASAIDYVSAIGLARIARHEADLLNYATQKMTVLPGLTIHGTSTRKAAVISFTMDCAHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCEEEEEEEECCCCC
HDMATLLDRSGVCIRVGHHCAQPLMARLGVSATARASFALYNTRADVDAFVKALEKVRAF
HHHHHHHCCCCCEEEECHHHHHHHHHHHCCCHHHCEEEEEEECCCCHHHHHHHHHHHHHH
FA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]