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The map label for this gene is yiaJ [H]

Identifier: 83593646

GI number: 83593646

Start: 2674570

End: 2675358

Strand: Reverse

Name: yiaJ [H]

Synonym: Rru_A2311

Alternate gene names: 83593646

Gene position: 2675358-2674570 (Counterclockwise)

Preceding gene: 83593651

Following gene: 83593643

Centisome position: 61.46

GC content: 65.4

Gene sequence:

>789_bases
ATGTCCAATTCCCCTCCCGACGGTGAAGGGTCTTCCGACGGGAAGCGCTCGGCGACCATCCAATCGGTCTCGATCGCCGC
GCGTTTTCTGACCATTTTGGCCAATGCCGAGGAGCCGCTCGCCCTTGGCACCCTGGCGCGGCGCGCCGGAACCGGCGGCT
CCACCGCCCATCGCTATGTGCAAAGTCTGGTTAAGGAGGGCTTGGCCAAGCAAGACAGCGTTAGCGGCTTTTATGATCTG
GGACCGCTGGCGCTGAGTGTCGGGATCGCCGCCCTTAAGCGGACCGACGCCGTCGAGATCGCCGCCCGGCATATGAAAGC
TTTGGCCAACCGCATCGCCGCCAGCGCCGGGGTCGCCATCTGGACCGAACGCGGGCCGACGCTGGTACGCTGGTATCGCA
GCGCCTATTTCTCGATCAGTTCTTTAGCCCTGGGGGATATTCTGCCGCTTGACAACACCGCCTGCGGGCTGGTGTTTCAG
GCCTTCCTGACGCCCAACCATATCGACGTGGCCCGGCGTCTTCAGCCCGATTACTTTCGCGGCACCCCGCCGTCTTCGGA
AACCCTGGCGCGGATCCGGCAAACCCGGGGCGCCGAGTTGACCGGCCATCTTCTGCCGGAAATCACCGGTCAGGCCGTGC
CGGTTTTCGACGCCCAGCAAGAACTCGTCTGCGTGATGACGACGGTGACCAATCTGGGACGGACCGGGGATCGGGCCGAC
CGCGAGGCCTTGTTCGAGACCGCCCGGGCGGTGGCGCGCGAAACCGGCGGCGACGCCTCGTTCGCCTGA

Upstream 100 bases:

>100_bases
GGGAATACCGGAGTGGATTGACAGCGCTGCCCGGGCGATATAGGGCCGGGTCCTCCGGCTTTCCGGCAATCGGGATCGTT
AGGCGAAGGGTTCGTTTTCC

Downstream 100 bases:

>100_bases
CCCCGGCGGGCCCGCCGCTTTCCCGCCGCCGCGCTCCTCCGGGGGCCGTTACATCGGTCGGCTGAGGGAGAAGATGCCGC
GTAAGTCGCCGGGCTTGAAG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: YiaKLMNOPQRS operon repressor; YiaK-S operon repressor [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSNSPPDGEGSSDGKRSATIQSVSIAARFLTILANAEEPLALGTLARRAGTGGSTAHRYVQSLVKEGLAKQDSVSGFYDL
GPLALSVGIAALKRTDAVEIAARHMKALANRIAASAGVAIWTERGPTLVRWYRSAYFSISSLALGDILPLDNTACGLVFQ
AFLTPNHIDVARRLQPDYFRGTPPSSETLARIRQTRGAELTGHLLPEITGQAVPVFDAQQELVCVMTTVTNLGRTGDRAD
REALFETARAVARETGGDASFA

Sequences:

>Translated_262_residues
MSNSPPDGEGSSDGKRSATIQSVSIAARFLTILANAEEPLALGTLARRAGTGGSTAHRYVQSLVKEGLAKQDSVSGFYDL
GPLALSVGIAALKRTDAVEIAARHMKALANRIAASAGVAIWTERGPTLVRWYRSAYFSISSLALGDILPLDNTACGLVFQ
AFLTPNHIDVARRLQPDYFRGTPPSSETLARIRQTRGAELTGHLLPEITGQAVPVFDAQQELVCVMTTVTNLGRTGDRAD
REALFETARAVARETGGDASFA
>Mature_261_residues
SNSPPDGEGSSDGKRSATIQSVSIAARFLTILANAEEPLALGTLARRAGTGGSTAHRYVQSLVKEGLAKQDSVSGFYDLG
PLALSVGIAALKRTDAVEIAARHMKALANRIAASAGVAIWTERGPTLVRWYRSAYFSISSLALGDILPLDNTACGLVFQA
FLTPNHIDVARRLQPDYFRGTPPSSETLARIRQTRGAELTGHLLPEITGQAVPVFDAQQELVCVMTTVTNLGRTGDRADR
EALFETARAVARETGGDASFA

Specific function: Negatively controls the transcription of the yiaKLMNOPQRS operon, which may be involved in the utilization of 2,3-diketo-L-gulonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789999, Length=264, Percent_Identity=25.3787878787879, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27812; Mature: 27681

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSPPDGEGSSDGKRSATIQSVSIAARFLTILANAEEPLALGTLARRAGTGGSTAHRYV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHH
QSLVKEGLAKQDSVSGFYDLGPLALSVGIAALKRTDAVEIAARHMKALANRIAASAGVAI
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
WTERGPTLVRWYRSAYFSISSLALGDILPLDNTACGLVFQAFLTPNHIDVARRLQPDYFR
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCC
GTPPSSETLARIRQTRGAELTGHLLPEITGQAVPVFDAQQELVCVMTTVTNLGRTGDRAD
CCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
REALFETARAVARETGGDASFA
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNSPPDGEGSSDGKRSATIQSVSIAARFLTILANAEEPLALGTLARRAGTGGSTAHRYV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHH
QSLVKEGLAKQDSVSGFYDLGPLALSVGIAALKRTDAVEIAARHMKALANRIAASAGVAI
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
WTERGPTLVRWYRSAYFSISSLALGDILPLDNTACGLVFQAFLTPNHIDVARRLQPDYFR
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCC
GTPPSSETLARIRQTRGAELTGHLLPEITGQAVPVFDAQQELVCVMTTVTNLGRTGDRAD
CCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
REALFETARAVARETGGDASFA
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]