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The map label for this gene is bigR [H]

Identifier: 83593643

GI number: 83593643

Start: 2671748

End: 2672080

Strand: Reverse

Name: bigR [H]

Synonym: Rru_A2308

Alternate gene names: 83593643

Gene position: 2672080-2671748 (Counterclockwise)

Preceding gene: 83593646

Following gene: 83593642

Centisome position: 61.39

GC content: 58.56

Gene sequence:

>333_bases
ATGGTTGCGGAAAATTCCACCCTTAGTGTCGATGCCATGCGAACGGCCGCCGCGGAAGCGACGGCGACCTTGTTCGCCCT
GGCCAATCAGAACCGGCTGTTGCTGCTTTGTCAGTTGTGCAATGGCGAGATGTCGGTAAGCGCCCTGGAAGAGGCGCTGG
GGATTCATCAGCCGACGCTGTCCCAACAGCTTGGCGTTTTGCGCTCCGAAGGATTGATCGCCAGCCGGCGCGAGGGGAAG
CGGATTTATTACTCGGTCGCCAACCCCAAAGTCCTGGTGCTGATCAACACCCTGGTCGATCTGTATTGTCCGCAGAAAAG
GGACCTCCCATGA

Upstream 100 bases:

>100_bases
GCTTTGAAGGGGCGATCGGCGGTCACGACGACGACCGTGGCACCGACCCTATTGCGGTAAGTTATATTAGTCAATATAAT
GATGATATATCGGAGGTCGC

Downstream 100 bases:

>100_bases
CCTTTGACGCCGTCCCCCGTTACGCCGCCCCCCGTCAGGCCGCTTGCGGCGGCCGCGCCCCAAGCGCGGCGCGGGGGAGC
GTCATGGGCTGGAGTCGCGC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MVAENSTLSVDAMRTAAAEATATLFALANQNRLLLLCQLCNGEMSVSALEEALGIHQPTLSQQLGVLRSEGLIASRREGK
RIYYSVANPKVLVLINTLVDLYCPQKRDLP

Sequences:

>Translated_110_residues
MVAENSTLSVDAMRTAAAEATATLFALANQNRLLLLCQLCNGEMSVSALEEALGIHQPTLSQQLGVLRSEGLIASRREGK
RIYYSVANPKVLVLINTLVDLYCPQKRDLP
>Mature_110_residues
MVAENSTLSVDAMRTAAAEATATLFALANQNRLLLLCQLCNGEMSVSALEEALGIHQPTLSQQLGVLRSEGLIASRREGK
RIYYSVANPKVLVLINTLVDLYCPQKRDLP

Specific function: Represses an operon that comprises at least itself and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=94, Percent_Identity=40.4255319148936, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11972; Mature: 11972

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAENSTLSVDAMRTAAAEATATLFALANQNRLLLLCQLCNGEMSVSALEEALGIHQPTL
CCCCCCEEEHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCH
SQQLGVLRSEGLIASRREGKRIYYSVANPKVLVLINTLVDLYCPQKRDLP
HHHHHHHHCCCCEECCCCCCEEEEEECCCEEEEEHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVAENSTLSVDAMRTAAAEATATLFALANQNRLLLLCQLCNGEMSVSALEEALGIHQPTL
CCCCCCEEEHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCH
SQQLGVLRSEGLIASRREGKRIYYSVANPKVLVLINTLVDLYCPQKRDLP
HHHHHHHHCCCCEECCCCCCEEEEEECCCEEEEEHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]