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The map label for this gene is ribB

Identifier: 83593532

GI number: 83593532

Start: 2551477

End: 2552121

Strand: Direct

Name: ribB

Synonym: Rru_A2197

Alternate gene names: 83593532

Gene position: 2551477-2552121 (Clockwise)

Preceding gene: 83593529

Following gene: 83593539

Centisome position: 58.62

GC content: 67.75

Gene sequence:

>645_bases
ATGAATCAGATCTTTGCCAATCCCCTCTCTCTTCCCGGCACCGCCCAGGAGCGGGTTTCCCGCGCCGTTGACAGCCTGCG
CCAGGGCCAGGGGGTCATCGTCGTTGACGATGAGGACCGCGAAAACGAGGGAGACCTTATTTTCGCCGCCGAAACCCTGA
CAGCCGAACAGATGAGCCGGATGATCCGCGATGGCTCGGGCATCGTTTGCCTGATCCTGACCGACCCCGACCTTGATCGT
CTGGCTTTGCCGCCGATGGTCGCCCACAACACCTCGCGCAACGGCACCGGCTTTACCGTCTCGATCGAGGCGCGCGAGGG
CGTGACCACCGGGGTCTCGGCCGCCGATCGGGTCACCACCATCCGCGCCGCCATCGATCCCGCCAGCACCGCCGATGATC
TGGCCCGCCCCGGCCACGTCTTCCCCTTGCGCGCCCATGCCGATGGCCTGAGCGCGCGCCGGGGCCATACCGAGGCGACC
ATCGCCCTGATGAGGTTGGCGGGGCTGCGCCCGGCCGGGGTGCTGTGCGAGGTGATGAACCCCGATGGCACCATGGCCCG
CCTGCCGACCCTGATCGGCTATGGCCAAGCCCATGGCCTGCCCATCGTCAGCATCGAGGATCTGGTCGCCGTCGGCGCCC
GCTGA

Upstream 100 bases:

>100_bases
GGCGCTTTGCTCACACCCTGGAAGGCGGACTCCTGTCCGCCGCCCGGGGAAGTCCTCTGCCGCCCTGATTCAGGCTCGCC
CAGTCTTAAAGGTGAGAACC

Downstream 100 bases:

>100_bases
TCCTTTTGCGGCGGCACCGGGCGGGGCTTGTCGCCAAGCGGCGCCGCCGCCGGTTTTCCTAGAGCGGTGAGCGGGGACTA
GATTTCACGCTCACCGCTCT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MNQIFANPLSLPGTAQERVSRAVDSLRQGQGVIVVDDEDRENEGDLIFAAETLTAEQMSRMIRDGSGIVCLILTDPDLDR
LALPPMVAHNTSRNGTGFTVSIEAREGVTTGVSAADRVTTIRAAIDPASTADDLARPGHVFPLRAHADGLSARRGHTEAT
IALMRLAGLRPAGVLCEVMNPDGTMARLPTLIGYGQAHGLPIVSIEDLVAVGAR

Sequences:

>Translated_214_residues
MNQIFANPLSLPGTAQERVSRAVDSLRQGQGVIVVDDEDRENEGDLIFAAETLTAEQMSRMIRDGSGIVCLILTDPDLDR
LALPPMVAHNTSRNGTGFTVSIEAREGVTTGVSAADRVTTIRAAIDPASTADDLARPGHVFPLRAHADGLSARRGHTEAT
IALMRLAGLRPAGVLCEVMNPDGTMARLPTLIGYGQAHGLPIVSIEDLVAVGAR
>Mature_214_residues
MNQIFANPLSLPGTAQERVSRAVDSLRQGQGVIVVDDEDRENEGDLIFAAETLTAEQMSRMIRDGSGIVCLILTDPDLDR
LALPPMVAHNTSRNGTGFTVSIEAREGVTTGVSAADRVTTIRAAIDPASTADDLARPGHVFPLRAHADGLSARRGHTEAT
IALMRLAGLRPAGVLCEVMNPDGTMARLPTLIGYGQAHGLPIVSIEDLVAVGAR

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=210, Percent_Identity=62.8571428571429, Blast_Score=253, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6320695, Length=198, Percent_Identity=43.4343434343434, Blast_Score=171, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_RHORT (Q2RS98)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_427284.1
- STRING:   Q2RS98
- GeneID:   3835624
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2197
- NMPDR:   fig|1085.1.peg.3674
- eggNOG:   COG0108
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- PhylomeDB:   Q2RS98
- BioCyc:   RRUB269796:RRU_A2197-MONOMER
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 22597; Mature: 22597

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: BINDING 45-45 BINDING 177-177

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIFANPLSLPGTAQERVSRAVDSLRQGQGVIVVDDEDRENEGDLIFAAETLTAEQMSR
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEHHHHHHHHHH
MIRDGSGIVCLILTDPDLDRLALPPMVAHNTSRNGTGFTVSIEAREGVTTGVSAADRVTT
HHHCCCCEEEEEEECCCCCHHCCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHEE
IRAAIDPASTADDLARPGHVFPLRAHADGLSARRGHTEATIALMRLAGLRPAGVLCEVMN
EEECCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEC
PDGTMARLPTLIGYGQAHGLPIVSIEDLVAVGAR
CCCCHHHHHHHHCCCCCCCCEEEEHHHHHHCCCC
>Mature Secondary Structure
MNQIFANPLSLPGTAQERVSRAVDSLRQGQGVIVVDDEDRENEGDLIFAAETLTAEQMSR
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEHHHHHHHHHH
MIRDGSGIVCLILTDPDLDRLALPPMVAHNTSRNGTGFTVSIEAREGVTTGVSAADRVTT
HHHCCCCEEEEEEECCCCCHHCCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHEE
IRAAIDPASTADDLARPGHVFPLRAHADGLSARRGHTEATIALMRLAGLRPAGVLCEVMN
EEECCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEC
PDGTMARLPTLIGYGQAHGLPIVSIEDLVAVGAR
CCCCHHHHHHHHCCCCCCCCEEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA