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The map label for this gene is pntAB

Identifier: 83593517

GI number: 83593517

Start: 2534264

End: 2534683

Strand: Reverse

Name: pntAB

Synonym: Rru_A2182

Alternate gene names: 83593517

Gene position: 2534683-2534264 (Counterclockwise)

Preceding gene: 83593518

Following gene: 83593516

Centisome position: 58.23

GC content: 60.95

Gene sequence:

>420_bases
ATGGAAGACAAGAACATCCTCGTCGAGGGCTTCAATCAGCTCTCGCAACAGGCCCTTGAATTGTCCCAGCATGCCCAGGC
CCTGGCCCTTCAGGCCAGCCATGCGGTTCTGCCGGCCGCCGCCGCCACGGAAGGCGCCAGCGAGTTCTGGTGGCTGATGA
CGGTTTTCGTCCTGGCCTGCTTCATCGGCTTTTATGTGGTGTGGTCGGTGACCCCGGCCCTTCACAGCCCGCTGATGGGC
GTCACCAACGCCATTTCCTCGGTCATCGTCGTCGGGGCGCTGATCGCCACCGGTCCTGAAGCCTTCAGCGCGTCGAAGGT
GCTGGGCTTCTTCGCCATCCTGCTTGCGAGCGTGAACATCTTCGGCGGGTTCATCGTGACCCAACGAATGCTGGCCATGT
TCAAGAAGAAGCAGAAGTAA

Upstream 100 bases:

>100_bases
GCTGGTGATGAAGCTCGAGGACGAAACGGTTTCGGGCACCTGTGTGACCCGCGATGGCGCCATCGTCCATCCGGCGCTGA
CCGGACAGGGAGCATAAGCG

Downstream 100 bases:

>100_bases
GGGGCACGCGACCATGACGCATAGTCTTACCATGGCGGCCTATATCGTCGCCGGCGTGCTCTTCATTCTCGCCCTGCGCG
GCCTGTCCAATCCGGAATCG

Product: NAD(P)(+) transhydrogenase (AB-specific)

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MEDKNILVEGFNQLSQQALELSQHAQALALQASHAVLPAAAATEGASEFWWLMTVFVLACFIGFYVVWSVTPALHSPLMG
VTNAISSVIVVGALIATGPEAFSASKVLGFFAILLASVNIFGGFIVTQRMLAMFKKKQK

Sequences:

>Translated_139_residues
MEDKNILVEGFNQLSQQALELSQHAQALALQASHAVLPAAAATEGASEFWWLMTVFVLACFIGFYVVWSVTPALHSPLMG
VTNAISSVIVVGALIATGPEAFSASKVLGFFAILLASVNIFGGFIVTQRMLAMFKKKQK
>Mature_139_residues
MEDKNILVEGFNQLSQQALELSQHAQALALQASHAVLPAAAATEGASEFWWLMTVFVLACFIGFYVVWSVTPALHSPLMG
VTNAISSVIVVGALIATGPEAFSASKVLGFFAILLASVNIFGGFIVTQRMLAMFKKKQK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=90, Percent_Identity=52.2222222222222, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI122939153, Length=90, Percent_Identity=52.2222222222222, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1787887, Length=91, Percent_Identity=59.3406593406593, Blast_Score=108, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17550456, Length=92, Percent_Identity=48.9130434782609, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PNTAB_RHORT (Q2RSB3)

Other databases:

- EMBL:   U05294
- EMBL:   CP000230
- RefSeq:   YP_427269.1
- STRING:   Q2RSB3
- GeneID:   3835609
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2182
- NMPDR:   fig|1085.1.peg.3657
- eggNOG:   COG3288
- HOGENOM:   HBG289734
- OMA:   EGASEFW
- ProtClustDB:   CLSK2397385
- BioCyc:   RRUB269796:RRU_A2182-MONOMER

Pfam domain/function: NA

EC number: =1.6.1.2

Molecular weight: Translated: 14889; Mature: 14889

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfe4cf80)-; HASH(0x109e0b5c)-; HASH(0x1099d050)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKNILVEGFNQLSQQALELSQHAQALALQASHAVLPAAAATEGASEFWWLMTVFVLAC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FIGFYVVWSVTPALHSPLMGVTNAISSVIVVGALIATGPEAFSASKVLGFFAILLASVNI
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FGGFIVTQRMLAMFKKKQK
HHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MEDKNILVEGFNQLSQQALELSQHAQALALQASHAVLPAAAATEGASEFWWLMTVFVLAC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FIGFYVVWSVTPALHSPLMGVTNAISSVIVVGALIATGPEAFSASKVLGFFAILLASVNI
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FGGFIVTQRMLAMFKKKQK
HHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801