| Definition | Rhodospirillum rubrum ATCC 11170 chromosome, complete genome. |
|---|---|
| Accession | NC_007643 |
| Length | 4,352,825 |
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The map label for this gene is sdh [H]
Identifier: 83593462
GI number: 83593462
Start: 2469850
End: 2470617
Strand: Direct
Name: sdh [H]
Synonym: Rru_A2127
Alternate gene names: 83593462
Gene position: 2469850-2470617 (Clockwise)
Preceding gene: 83593456
Following gene: 83593463
Centisome position: 56.74
GC content: 67.71
Gene sequence:
>768_bases ATGACCAACACGGTTTTCATCACCGGCGCCACCGCCGGTTTTGGCGAGGCTTGCGCGCGGCGGTTCGCCGAGGCCGGCTG GGCCCTGGTGCTGACCGGCCGGCGGGCGGAGCGGCTGGAGGCGCTGAAGGCCGAATTGGGCGCCAGCGTGCCCGTTCACG CCGCGGTGATGGACGTGCGCGACCGCGCCTCGGTCCAGGCGGTAATCGCGGCTCTGCCCGCGCCGTTTGACAAGGTCCAT ACGCTGATCAACAACGCCGGTCTGGCGGCGGGGCTGGAAAAGGCCGCCGAGGCCTCGCTCGACGACTGGCAGACGATGAT CGACACCAATGTCACCGGTCTGGTCACCTGCACCCATGCCCTGCTGCCCCGGCTGATCGCGGCGGGCAACGGGTCGATCA TCAATCTTGGCTCGGTCGCCGGGCGCTGGCCCTATCCGGGCGGCAGCGTCTATGGCGGGACCAAGGCCTTCGTCCGCCAG TTCAGCCTGAATTTGCGCAATGACCTGCTGGGCACCGGGGTGCGGGTGACCGATATCGAACCAGGCATGGCCGAAAGCGA GTTTTCGATCGTGCGCTTCAAGGGCGACCGCGAGGCGGCCAGCAAGGTTTATGCCGGCGTCGATCCGCTGACCCCCAAGG ACATCGCCGAAACCATCTTCTGGGTCGCCACCCAGCCCCCCCATATTAACATCAACACCCTGGAAATCATGCCCGTCGCC CAGGCCTGGGCCGGCTTCGCCGTCCACCGCCGCCCCGCCGCCGAGTAG
Upstream 100 bases:
>100_bases TGCCCTTGACGACCGGGCCTTGGCCGCCAACCATCGGCCCGATCATGGGTTTGCCCGGTCCCGGCGCGATTTCGCCGGGG CTGCTGCGAGGAGAAGACGG
Downstream 100 bases:
>100_bases GCGGCCCACCCTTCGTCCGCCCCCGCGATGCCGGACACGCCCCTCCTCGCCTCTTCACAACCGGCCGCCGGGCGACGGGC GCTTGGCCTGTCGGCCCGGC
Product: serine 3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MTNTVFITGATAGFGEACARRFAEAGWALVLTGRRAERLEALKAELGASVPVHAAVMDVRDRASVQAVIAALPAPFDKVH TLINNAGLAAGLEKAAEASLDDWQTMIDTNVTGLVTCTHALLPRLIAAGNGSIINLGSVAGRWPYPGGSVYGGTKAFVRQ FSLNLRNDLLGTGVRVTDIEPGMAESEFSIVRFKGDREAASKVYAGVDPLTPKDIAETIFWVATQPPHININTLEIMPVA QAWAGFAVHRRPAAE
Sequences:
>Translated_255_residues MTNTVFITGATAGFGEACARRFAEAGWALVLTGRRAERLEALKAELGASVPVHAAVMDVRDRASVQAVIAALPAPFDKVH TLINNAGLAAGLEKAAEASLDDWQTMIDTNVTGLVTCTHALLPRLIAAGNGSIINLGSVAGRWPYPGGSVYGGTKAFVRQ FSLNLRNDLLGTGVRVTDIEPGMAESEFSIVRFKGDREAASKVYAGVDPLTPKDIAETIFWVATQPPHININTLEIMPVA QAWAGFAVHRRPAAE >Mature_254_residues TNTVFITGATAGFGEACARRFAEAGWALVLTGRRAERLEALKAELGASVPVHAAVMDVRDRASVQAVIAALPAPFDKVHT LINNAGLAAGLEKAAEASLDDWQTMIDTNVTGLVTCTHALLPRLIAAGNGSIINLGSVAGRWPYPGGSVYGGTKAFVRQF SLNLRNDLLGTGVRVTDIEPGMAESEFSIVRFKGDREAASKVYAGVDPLTPKDIAETIFWVATQPPHININTLEIMPVAQ AWAGFAVHRRPAAE
Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me
COG id: COG4221
COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=29.4354838709677, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=34.1968911917098, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI40548397, Length=187, Percent_Identity=32.620320855615, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI214010158, Length=187, Percent_Identity=32.620320855615, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI214010156, Length=187, Percent_Identity=32.620320855615, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI22758144, Length=187, Percent_Identity=32.620320855615, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=31.0526315789474, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI157739938, Length=230, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI119392083, Length=193, Percent_Identity=29.0155440414508, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7705855, Length=199, Percent_Identity=26.1306532663317, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI150247226, Length=193, Percent_Identity=30.0518134715026, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI22507405, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI19923817, Length=194, Percent_Identity=25.2577319587629, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI50726952, Length=189, Percent_Identity=33.8624338624339, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4557649, Length=181, Percent_Identity=29.8342541436464, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI32483357, Length=223, Percent_Identity=24.2152466367713, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI19743808, Length=230, Percent_Identity=26.5217391304348, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI44680136, Length=258, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI44680133, Length=258, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI17738292, Length=258, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI40254992, Length=191, Percent_Identity=27.7486910994764, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787820, Length=248, Percent_Identity=57.258064516129, Blast_Score=293, Evalue=5e-81, Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=38.2198952879581, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=28.6885245901639, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=27.9569892473118, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI87082160, Length=190, Percent_Identity=26.8421052631579, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI2367175, Length=191, Percent_Identity=26.1780104712042, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17559104, Length=236, Percent_Identity=29.6610169491525, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17560332, Length=241, Percent_Identity=32.3651452282158, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562904, Length=194, Percent_Identity=31.4432989690722, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17562990, Length=193, Percent_Identity=33.160621761658, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71994600, Length=234, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=219, Percent_Identity=31.0502283105023, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560150, Length=240, Percent_Identity=30.4166666666667, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI71994604, Length=233, Percent_Identity=26.6094420600858, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562910, Length=192, Percent_Identity=29.6875, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17563726, Length=239, Percent_Identity=30.9623430962343, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538486, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562908, Length=191, Percent_Identity=29.8429319371728, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17538480, Length=200, Percent_Identity=30, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560676, Length=194, Percent_Identity=26.8041237113402, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193204405, Length=186, Percent_Identity=31.7204301075269, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560220, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17544670, Length=241, Percent_Identity=28.2157676348548, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17562906, Length=191, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17551412, Length=241, Percent_Identity=25.7261410788382, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI115534660, Length=260, Percent_Identity=24.2307692307692, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17531453, Length=238, Percent_Identity=27.7310924369748, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI72000259, Length=239, Percent_Identity=27.6150627615063, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI25152911, Length=202, Percent_Identity=29.2079207920792, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17507613, Length=237, Percent_Identity=24.8945147679325, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI32563809, Length=237, Percent_Identity=24.8945147679325, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17508895, Length=181, Percent_Identity=27.6243093922652, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=40, Blast_Score=186, Evalue=2e-48, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=26.0204081632653, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6319635, Length=203, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=5e-13, Organism=Saccharomyces cerevisiae, GI6322067, Length=204, Percent_Identity=28.4313725490196, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI116007236, Length=249, Percent_Identity=30.9236947791165, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21358495, Length=240, Percent_Identity=27.9166666666667, Blast_Score=100, Evalue=7e-22, Organism=Drosophila melanogaster, GI23397609, Length=181, Percent_Identity=34.2541436464088, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI21357041, Length=201, Percent_Identity=31.3432835820896, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24640442, Length=202, Percent_Identity=30.1980198019802, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI28571526, Length=184, Percent_Identity=33.1521739130435, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24584748, Length=181, Percent_Identity=31.4917127071823, Blast_Score=87, Evalue=2e-17, Organism=Drosophila melanogaster, GI161076933, Length=177, Percent_Identity=31.638418079096, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24648944, Length=235, Percent_Identity=26.3829787234043, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24644339, Length=230, Percent_Identity=29.1304347826087, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24641388, Length=252, Percent_Identity=28.968253968254, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI116007238, Length=183, Percent_Identity=32.7868852459016, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI281364494, Length=251, Percent_Identity=27.0916334661355, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI116007234, Length=250, Percent_Identity=30, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24641232, Length=251, Percent_Identity=26.2948207171315, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24643142, Length=177, Percent_Identity=31.638418079096, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24648693, Length=248, Percent_Identity=27.0161290322581, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI21355889, Length=248, Percent_Identity=27.0161290322581, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI28571387, Length=248, Percent_Identity=26.2096774193548, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24663911, Length=248, Percent_Identity=24.5967741935484, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24584752, Length=181, Percent_Identity=28.1767955801105, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=28.8770053475936, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=28.8770053475936, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI21355319, Length=191, Percent_Identity=25.6544502617801, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.276 [H]
Molecular weight: Translated: 27031; Mature: 26900
Theoretical pI: Translated: 6.68; Mature: 6.68
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTNTVFITGATAGFGEACARRFAEAGWALVLTGRRAERLEALKAELGASVPVHAAVMDVR CCCEEEEEECCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHH DRASVQAVIAALPAPFDKVHTLINNAGLAAGLEKAAEASLDDWQTMIDTNVTGLVTCTHA HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH LLPRLIAAGNGSIINLGSVAGRWPYPGGSVYGGTKAFVRQFSLNLRNDLLGTGVRVTDIE HHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECC PGMAESEFSIVRFKGDREAASKVYAGVDPLTPKDIAETIFWVATQPPHININTLEIMPVA CCCCCCCEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHEEEECCCCCCCEEEEEEEEHH QAWAGFAVHRRPAAE HHHHCHHHCCCCCCC >Mature Secondary Structure TNTVFITGATAGFGEACARRFAEAGWALVLTGRRAERLEALKAELGASVPVHAAVMDVR CCEEEEEECCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHH DRASVQAVIAALPAPFDKVHTLINNAGLAAGLEKAAEASLDDWQTMIDTNVTGLVTCTHA HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH LLPRLIAAGNGSIINLGSVAGRWPYPGGSVYGGTKAFVRQFSLNLRNDLLGTGVRVTDIE HHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECC PGMAESEFSIVRFKGDREAASKVYAGVDPLTPKDIAETIFWVATQPPHININTLEIMPVA CCCCCCCEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHEEEECCCCCCCEEEEEEEEHH QAWAGFAVHRRPAAE HHHHCHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11743193; 11743194 [H]