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The map label for this gene is pgm [H]

Identifier: 83593450

GI number: 83593450

Start: 2454473

End: 2456107

Strand: Reverse

Name: pgm [H]

Synonym: Rru_A2115

Alternate gene names: 83593450

Gene position: 2456107-2454473 (Counterclockwise)

Preceding gene: 83593451

Following gene: 83593449

Centisome position: 56.43

GC content: 65.75

Gene sequence:

>1635_bases
ATGACCGTCACGGTTCTGGAGGTTCCAACCACGCCGTTCGCCGGGCAGAAACCCGGAACCTCGGGTCTGCGCAAGAAGGT
CGGCGTTTTTCGCCAGCCCCATTATCTCGAGAACTTCGTCCAGGCGGTCTTTGATAGCCTGGACGGCTTCCAGGGCCAGA
CCCTGGTGGTGGGCGGCGACGGGCGCTTCCATAACCGCGAGGCGGTGCAGACCATCTTGAAGATGGCGGCGGCCAACGGC
TTTGGCCGGGTGCTGGTCGGCCGCGACGGTCTGCTGTCGACGCCGGCGGCCTCTTGCGTGATCCGCGCCCATAAGGCCTT
TGGCGGCATCATCTTGTCGGCCAGCCATAATCCCGGCGGGCCCGAGGGCGATTTCGGCATCAAATACAACATCGGCGCCG
GCGGACCGGCCCCCGAAAAGATCACCGACGCCATCTTCGCCGCCACCGCCTCGCTCTCGCGTTATCGGACGCTGGAGAAT
GCTCCCGAGGTCGATCTTGGCCGGATCGGCGAGACGGATCTGGGCGGGATGCGGGTGGTCGTCATCGATCCGGTGGCCGA
TTACGCGGCGCTGATGGAAACCTTGTTCGACATGGAGGCCATTCGCCGCCTGTTCCGCGACGGCTTCACCATGTGTTTTG
ACGCCATGCACGCCGTCACCGGCCCTTACGCCCACGCCATCTTGGAAGGCCGGCTGGGCGCGCCGGCGGGAACCGTCATC
AACGGCACGCCGCTTGAGGATTTCGGCGGTGGCCATCCCGATCCCAATCTGACCTATGCCAAGGATCTGGCCGATCTGAT
GATGGGCGACCGGGCGCCCGATTTCGGCGCCGCCAGCGATGGCGACGGCGATCGCAACATGATTTTGGGCCGGGGCGTCT
TCGTCAATCCCTCCGACAGTCTGGCCGTTCTCGCCGCCAATGCCGAACTGATTCCGGGCTATCGCGGCCGGATGACCGGG
GTCGCCCGCTCGATGCCGACCAGCCGGGCCGTTGACCGGGTGGCGGCCAAGCGCGGCTGGGAATGCCACGAGACGCCGAC
CGGCTGGAAATTCTTCGGCACCCTGCTCGATGCCGGGCGGGCGACGCTGTGCGGCGAGGAAAGCTTCGGCACCGGTTCGG
ACCATGTGCGCGAAAAGGATGGGCTGTGGGCGGTGCTCGCTTGGCTCAACATCATCGCCGCGCGCGCTCAGACCGTTCGT
CAGATCCTGGCCGACCATTGGGGCAATTACGGCCGCACCTTCTATTCCCGCCACGACCACGAGGGGCTGGACGCGGCCAA
GGCCGAGGCGCTGATGGCCGATCTGCGCGCAGCCCCGCTGCTTGGCCAGACCCTTGGCGGGCGCAAGGTCGCCCTTCACG
ATGATTTCGCCTATACCGATCCCATCGACGGGTCGACCAGTCAGGGGCAGGGTATCCGCATCGAGTTTGAAGATGGGGCG
CGCATTGTCGTCCGGCTTTCGGGAACGGGAACGGAAGGCGCCACCTTGCGGCTATACCTCGAGCGCTTCGAGCCCGATCC
CGCCGCCCATGATCAGGATGCCCAAGTCGCCCTGGCCGATCTGATCGCCACCATCCGCGACCTGACCCGCCTCAAGGACC
GCTTCGGATCGGAAGATCCGACGGTCATCACCTGA

Upstream 100 bases:

>100_bases
ACGACATGGAGGCCCAGGGCTTCCGCTATAGCCCGATCGGCCGCCGCTCGGTGGGCTGATCCGTCGGGAAGCCTGTCTTT
TCCAGGGGGAGTGCTGTTCC

Downstream 100 bases:

>100_bases
TCCCTTTCGGATCTTGATTTGATCCCTTTGGGATCTTTGGCAAGGTCGCCCTTTCGGAAGCAGTACGCCCGTGACGCCAA
ACGCTCCCCCCCGCCCATCG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MTVTVLEVPTTPFAGQKPGTSGLRKKVGVFRQPHYLENFVQAVFDSLDGFQGQTLVVGGDGRFHNREAVQTILKMAAANG
FGRVLVGRDGLLSTPAASCVIRAHKAFGGIILSASHNPGGPEGDFGIKYNIGAGGPAPEKITDAIFAATASLSRYRTLEN
APEVDLGRIGETDLGGMRVVVIDPVADYAALMETLFDMEAIRRLFRDGFTMCFDAMHAVTGPYAHAILEGRLGAPAGTVI
NGTPLEDFGGGHPDPNLTYAKDLADLMMGDRAPDFGAASDGDGDRNMILGRGVFVNPSDSLAVLAANAELIPGYRGRMTG
VARSMPTSRAVDRVAAKRGWECHETPTGWKFFGTLLDAGRATLCGEESFGTGSDHVREKDGLWAVLAWLNIIAARAQTVR
QILADHWGNYGRTFYSRHDHEGLDAAKAEALMADLRAAPLLGQTLGGRKVALHDDFAYTDPIDGSTSQGQGIRIEFEDGA
RIVVRLSGTGTEGATLRLYLERFEPDPAAHDQDAQVALADLIATIRDLTRLKDRFGSEDPTVIT

Sequences:

>Translated_544_residues
MTVTVLEVPTTPFAGQKPGTSGLRKKVGVFRQPHYLENFVQAVFDSLDGFQGQTLVVGGDGRFHNREAVQTILKMAAANG
FGRVLVGRDGLLSTPAASCVIRAHKAFGGIILSASHNPGGPEGDFGIKYNIGAGGPAPEKITDAIFAATASLSRYRTLEN
APEVDLGRIGETDLGGMRVVVIDPVADYAALMETLFDMEAIRRLFRDGFTMCFDAMHAVTGPYAHAILEGRLGAPAGTVI
NGTPLEDFGGGHPDPNLTYAKDLADLMMGDRAPDFGAASDGDGDRNMILGRGVFVNPSDSLAVLAANAELIPGYRGRMTG
VARSMPTSRAVDRVAAKRGWECHETPTGWKFFGTLLDAGRATLCGEESFGTGSDHVREKDGLWAVLAWLNIIAARAQTVR
QILADHWGNYGRTFYSRHDHEGLDAAKAEALMADLRAAPLLGQTLGGRKVALHDDFAYTDPIDGSTSQGQGIRIEFEDGA
RIVVRLSGTGTEGATLRLYLERFEPDPAAHDQDAQVALADLIATIRDLTRLKDRFGSEDPTVIT
>Mature_543_residues
TVTVLEVPTTPFAGQKPGTSGLRKKVGVFRQPHYLENFVQAVFDSLDGFQGQTLVVGGDGRFHNREAVQTILKMAAANGF
GRVLVGRDGLLSTPAASCVIRAHKAFGGIILSASHNPGGPEGDFGIKYNIGAGGPAPEKITDAIFAATASLSRYRTLENA
PEVDLGRIGETDLGGMRVVVIDPVADYAALMETLFDMEAIRRLFRDGFTMCFDAMHAVTGPYAHAILEGRLGAPAGTVIN
GTPLEDFGGGHPDPNLTYAKDLADLMMGDRAPDFGAASDGDGDRNMILGRGVFVNPSDSLAVLAANAELIPGYRGRMTGV
ARSMPTSRAVDRVAAKRGWECHETPTGWKFFGTLLDAGRATLCGEESFGTGSDHVREKDGLWAVLAWLNIIAARAQTVRQ
ILADHWGNYGRTFYSRHDHEGLDAAKAEALMADLRAAPLLGQTLGGRKVALHDDFAYTDPIDGSTSQGQGIRIEFEDGAR
IVVRLSGTGTEGATLRLYLERFEPDPAAHDQDAQVALADLIATIRDLTRLKDRFGSEDPTVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=562, Percent_Identity=53.202846975089, Blast_Score=588, Evalue=1e-168,
Organism=Homo sapiens, GI21361621, Length=564, Percent_Identity=52.4822695035461, Blast_Score=582, Evalue=1e-166,
Organism=Homo sapiens, GI133922562, Length=564, Percent_Identity=49.468085106383, Blast_Score=538, Evalue=1e-153,
Organism=Homo sapiens, GI290463104, Length=367, Percent_Identity=53.133514986376, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI239741729, Length=135, Percent_Identity=47.4074074074074, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI239743670, Length=135, Percent_Identity=47.4074074074074, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI1786904, Length=479, Percent_Identity=27.1398747390397, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17535441, Length=571, Percent_Identity=50.9632224168126, Blast_Score=533, Evalue=1e-151,
Organism=Saccharomyces cerevisiae, GI6322722, Length=572, Percent_Identity=46.5034965034965, Blast_Score=509, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6323752, Length=571, Percent_Identity=45.8844133099825, Blast_Score=509, Evalue=1e-145,
Organism=Drosophila melanogaster, GI17864244, Length=565, Percent_Identity=50.0884955752212, Blast_Score=532, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58167; Mature: 58036

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTVLEVPTTPFAGQKPGTSGLRKKVGVFRQPHYLENFVQAVFDSLDGFQGQTLVVGGD
CEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECC
GRFHNREAVQTILKMAAANGFGRVLVGRDGLLSTPAASCVIRAHKAFGGIILSASHNPGG
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCC
PEGDFGIKYNIGAGGPAPEKITDAIFAATASLSRYRTLENAPEVDLGRIGETDLGGMRVV
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
VIDPVADYAALMETLFDMEAIRRLFRDGFTMCFDAMHAVTGPYAHAILEGRLGAPAGTVI
EECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEE
NGTPLEDFGGGHPDPNLTYAKDLADLMMGDRAPDFGAASDGDGDRNMILGRGVFVNPSDS
CCCCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCEEECCCCC
LAVLAANAELIPGYRGRMTGVARSMPTSRAVDRVAAKRGWECHETPTGWKFFGTLLDAGR
EEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
ATLCGEESFGTGSDHVREKDGLWAVLAWLNIIAARAQTVRQILADHWGNYGRTFYSRHDH
CEECCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
EGLDAAKAEALMADLRAAPLLGQTLGGRKVALHDDFAYTDPIDGSTSQGQGIRIEFEDGA
CCCCHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCC
RIVVRLSGTGTEGATLRLYLERFEPDPAAHDQDAQVALADLIATIRDLTRLKDRFGSEDP
EEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVIT
CEEC
>Mature Secondary Structure 
TVTVLEVPTTPFAGQKPGTSGLRKKVGVFRQPHYLENFVQAVFDSLDGFQGQTLVVGGD
EEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECC
GRFHNREAVQTILKMAAANGFGRVLVGRDGLLSTPAASCVIRAHKAFGGIILSASHNPGG
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCC
PEGDFGIKYNIGAGGPAPEKITDAIFAATASLSRYRTLENAPEVDLGRIGETDLGGMRVV
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
VIDPVADYAALMETLFDMEAIRRLFRDGFTMCFDAMHAVTGPYAHAILEGRLGAPAGTVI
EECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEE
NGTPLEDFGGGHPDPNLTYAKDLADLMMGDRAPDFGAASDGDGDRNMILGRGVFVNPSDS
CCCCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCEEECCCCC
LAVLAANAELIPGYRGRMTGVARSMPTSRAVDRVAAKRGWECHETPTGWKFFGTLLDAGR
EEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
ATLCGEESFGTGSDHVREKDGLWAVLAWLNIIAARAQTVRQILADHWGNYGRTFYSRHDH
CEECCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
EGLDAAKAEALMADLRAAPLLGQTLGGRKVALHDDFAYTDPIDGSTSQGQGIRIEFEDGA
CCCCHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCC
RIVVRLSGTGTEGATLRLYLERFEPDPAAHDQDAQVALADLIATIRDLTRLKDRFGSEDP
EEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVIT
CEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]