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The map label for this gene is can [H]

Identifier: 83593391

GI number: 83593391

Start: 2378407

End: 2379048

Strand: Direct

Name: can [H]

Synonym: Rru_A2056

Alternate gene names: 83593391

Gene position: 2378407-2379048 (Clockwise)

Preceding gene: 83593390

Following gene: 83593392

Centisome position: 54.64

GC content: 60.75

Gene sequence:

>642_bases
GTGGACATCCAGGATCTCATTACCAACAATCGGAAATGGGCCGAGGAGCGCGAATCCGCCCTTCCTGGCTATTTTCATAT
CCTCAGCGAAGTGCAGTCGCCGAAGTTTTTGTGGATCGGCTGCTCGGACTCGCGGGTGCCGGCCAATGAAATCGTCGGCA
TGCAGCCGGGCGAACTTTTCGTTCACCGCAACATCGCCAACGTTGTTCCCCATGCCGACGCCAATTGCCACGCCGTGCTC
GAATACGCCATCGACGTGCTGAAGGTCGAGCACATCATGGTCGTCGGCCATTACGGCTGCGGCGGGGTTCGCGCCGCCCT
GAACCGTCTGGCCATGGGGCCGATCGACAACTGGCTGTCCCACATCAAGGACATCGCCCGTATCTTCGCCGCCGAGCTGG
AAGACCTACCCGACGAGGAAAGCCGGGTCGACCGGCTGTGCGAACTCAACGCCATGGCCCAGGTGATGAACGTGGCGCGC
ACCTCGATGGTTCAGGCGGCTTGGCGACGCGGCCAGCCTTTGGCCATCCACGCTTGGTGCTATGGTCTGAAGACTGGGCT
GGTCAATGATCTTGGCCGAACCCTAACCCGCATCGCCGATCTGCCCGAACCCTATCGGCTGATCTTTCCCGATCAGGTCT
AA

Upstream 100 bases:

>100_bases
AAGGACGGGCGGCGCGGCGCGCAAAAAGAAGCCGCTGGACGGCGGACGAAGAGCGGTCTAACACCGCCCGGCCATCGACC
AAGACAAGGTGATTCGTACC

Downstream 100 bases:

>100_bases
AAGAAACGCCCAGGAACGCTCCCCCATGAAATTGTTCGGCCTGACCGGCAAAAGCAACAGCGGCAAAACAACGTTGCTGA
TTGCGCTCATCCCGCTTCTG

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MDIQDLITNNRKWAEERESALPGYFHILSEVQSPKFLWIGCSDSRVPANEIVGMQPGELFVHRNIANVVPHADANCHAVL
EYAIDVLKVEHIMVVGHYGCGGVRAALNRLAMGPIDNWLSHIKDIARIFAAELEDLPDEESRVDRLCELNAMAQVMNVAR
TSMVQAAWRRGQPLAIHAWCYGLKTGLVNDLGRTLTRIADLPEPYRLIFPDQV

Sequences:

>Translated_213_residues
MDIQDLITNNRKWAEERESALPGYFHILSEVQSPKFLWIGCSDSRVPANEIVGMQPGELFVHRNIANVVPHADANCHAVL
EYAIDVLKVEHIMVVGHYGCGGVRAALNRLAMGPIDNWLSHIKDIARIFAAELEDLPDEESRVDRLCELNAMAQVMNVAR
TSMVQAAWRRGQPLAIHAWCYGLKTGLVNDLGRTLTRIADLPEPYRLIFPDQV
>Mature_213_residues
MDIQDLITNNRKWAEERESALPGYFHILSEVQSPKFLWIGCSDSRVPANEIVGMQPGELFVHRNIANVVPHADANCHAVL
EYAIDVLKVEHIMVVGHYGCGGVRAALNRLAMGPIDNWLSHIKDIARIFAAELEDLPDEESRVDRLCELNAMAQVMNVAR
TSMVQAAWRRGQPLAIHAWCYGLKTGLVNDLGRTLTRIADLPEPYRLIFPDQV

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=205, Percent_Identity=51.7073170731707, Blast_Score=232, Evalue=1e-62,
Organism=Escherichia coli, GI1786534, Length=194, Percent_Identity=30.9278350515464, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324292, Length=206, Percent_Identity=30.0970873786408, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23906; Mature: 23906

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQDLITNNRKWAEERESALPGYFHILSEVQSPKFLWIGCSDSRVPANEIVGMQPGELF
CCHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCHHE
VHRNIANVVPHADANCHAVLEYAIDVLKVEHIMVVGHYGCGGVRAALNRLAMGPIDNWLS
EECCHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCHHHHHH
HIKDIARIFAAELEDLPDEESRVDRLCELNAMAQVMNVARTSMVQAAWRRGQPLAIHAWC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHH
YGLKTGLVNDLGRTLTRIADLPEPYRLIFPDQV
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCC
>Mature Secondary Structure
MDIQDLITNNRKWAEERESALPGYFHILSEVQSPKFLWIGCSDSRVPANEIVGMQPGELF
CCHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCHHE
VHRNIANVVPHADANCHAVLEYAIDVLKVEHIMVVGHYGCGGVRAALNRLAMGPIDNWLS
EECCHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCHHHHHH
HIKDIARIFAAELEDLPDEESRVDRLCELNAMAQVMNVARTSMVQAAWRRGQPLAIHAWC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHH
YGLKTGLVNDLGRTLTRIADLPEPYRLIFPDQV
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]